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   慢性乙型重型肝炎 在 感染性疾病及传染病 分类中 的翻译结果: 查询用时:0.022秒
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慢性乙型重型肝炎     
相关语句
  chronic severe hepatitis b
    Clinical Effect of Thymosin Combined with Vidarabine on 24 Cases of Chronic Severe Hepatitis B Treatment
    胸腺素联合单磷酸阿糖腺苷治疗慢性乙型重型肝炎24例
短句来源
    The expression of B7 and CD28 in peripheral blood mononuclear cells of chronic severe hepatitis B patients and its clinical significance
    慢性乙型重型肝炎患者外周血单个核细胞 B7/CD28分子的表达及意义
短句来源
    Concentration variation of interleukin 18,interleukin 4 and γ interferon in serum from patients with chronic severe hepatitis B
    慢性乙型重型肝炎患者外周血白细胞介素18、白细胞介素4、γ干扰素的变化
短句来源
    Clinical observation of artifical liver supporting systems on the treatment of patients with chronic severe hepatitis B
    人工肝支持系统治疗慢性乙型重型肝炎的临床观察
短句来源
    The Clinical therapeutic effect in patient with chronic severe hepatitis B after infusing umbilical cord blood
    输注脐血对慢性乙型重型肝炎临床疗效的影响
短句来源
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  chronic severe type b hepatitis
    Evaluation of Patients Treated with Lipo-prostaglandin E 1 for Chronic Severe Type B Hepatitis by MELD Prognosis Analysis
    应用MELD预后分析评价前列腺素E_1脂微球载体制剂治疗慢性乙型重型肝炎的疗效
短句来源
    OBJECTIVE:To investigate the therapeutic effect of Lipo-prostaglandin E 1 (Lipo PGE 1 )on chronic severe type B hepatitis by MELD(Model for end-stage live disease)prognosis analysis.
    目的:应用终末期肝病模型(MELD)预后分析研究前列腺素E1脂微球载体制剂(LipoPGE1)对慢性乙型重型肝炎的治疗作用。
短句来源
    METHODS:Of a total of115cases with chronic severe type B hepatitis,57were randomly assigned to receive a common combined therapy and58to receive a common combined therapy plus Lipo PGE 1 for4weeks,the MELD score and prognosis of diseases of the2groups were assessed.
    方法:115例慢性乙型重型肝炎随机分成对照组、治疗组,对照组57例采用一般综合治疗,治疗组58例在一般综合治疗基础上加用LipoPGE1,疗程4wk,评价2组治疗后的MELD评分及疾病转归情况。
短句来源
    CONCLUSION:Lipo PGE 1 has a good therapeutic effect on chronic severe type B hepatitis.
    结论:LipoPGE1辅助治疗慢性乙型重型肝炎有良好疗效。
短句来源
  severe chronic hepatitis b
    Results The results of genotyping showed that among 50 patients with severe chronic hepatitis B 1 case (2%) was genotype B,43 cases(86%) were genotype C,6 cases(12%) were mixed genotypes (B and C). The mortality of genotype C and mixed genotypes were 39.5%(17/43) and 50%(3/6) respectively.
    结果50例慢性乙型重型肝炎患者B基因型1例(2%),C基因型43例(86%),BC混合基因型6例(12%);
短句来源
    Short-term therapeutic effect of lamivudine on patients with severe chronic hepatitis B.
    拉米夫定治疗慢性乙型重型肝炎的近期疗效
短句来源
    Genotypes and nucleotide polymorphisms in patients with severe chronic hepatitis B in Wuxi region
    慢性乙型重型肝炎HBV基因型和核苷酸多态性分析
短句来源
    Objective To explore the features of genotypes and nucleotide polymorphisms in the patients with severe chronic hepatitis B in Wuxi region.
    目的探讨无锡地区慢性乙型重型肝炎HBV基因型和核苷酸多态性分布的特点。
短句来源
    Conclusions The results suggest that the patients with severe chronic hepatitis B may related to both genotype C and mixed genotypes B and C,and all the three genotypes presented nucleotide polymorphisms.
    结论无锡地区慢性乙型重型肝炎多见于C、BC混合基因型,C、B、BC基因型核苷酸呈多态性改变。
短句来源
  chronic gravis of hepatitis b
    Study on Relationship between the Loads of Virus HBV DNA and TNF-α,IL1β,IL6 in Patients with Chronic Gravis of Hepatitis B
    慢性乙型重型肝炎中TNF-α,IL1β,IL6与病毒含量关系的研究
短句来源
    Objective To study the relationship between the loads of virus HBV DNA and TNF-α,IL1β,IL6 in patients with chronic gravis of hepatitis B.Methods The activities in the sera of 60 patients with chronic gravis of hepatitis B were detectd by ELISA and HBVDNA by PCR.
    目的探讨细胞因子TNF-α,IL1β,IL6在慢性乙型重型肝炎中与病毒含量的关系及其在重型肝炎中的作用和临床意义。 方法60例慢性乙型重型肝炎中的血清标本进行HBVDNA和TNF-α,IL1β,IL6的测定,方法分别采用荧光定量PCR和ELISA法,并进行临床观察。
短句来源
    Study on Relationship between the Content of HBV DNA and the Liver Function State in Patients with Chronic Gravis of Hepatitis B
    慢性乙型重型肝炎血清病毒载量与肝损伤的临床分析
短句来源
    The IL1β and IL6 activities in cured patients were higher than those in the death and TNF-α activities in cured patients were lower than those in the death P<0.05.Conclusion the loads of virus HBVDNA in patients with chronic gravis of hepatitis B influence the activities of cytokine TNF-α,IL1β,IL6.It is value in the to predict patient effect of cruing.
    另存活组病人TNF-α低,IL1,IL6升高较死亡组,P<0.05。 结论慢性乙型重型肝炎中病毒含量一定程度上影响着细胞因子的变化,影响病情预后,对临床有一定的指导意义。
短句来源

 

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  chronic severe hepatitis b
Discriminant function for prognostic indexes and probability of death in chronic severe hepatitis B
      
We aimed to determine a discriminant function for prognosis in chronic severe hepatitis B (CSHB), by discriminant analysis of prognostic indexes and probability of death.
      
The discriminant function is an objective, convenient, and practical method to assess the prognosis of chronic severe hepatitis B.
      
  其他


Objective: To observe relationship among cytokine level change in the sera of patients with chronic viral hepatic disease, viral replication and clinical significance. Methods: The TNF-α, IL-1, IL-6 and IL-8 activities in the sera of patients with chronic hepatitis B (CH), chronic severe hepatitis B (CSH) and hepatocirrhosis (HC) by ELISA. Results:The TNF-α, IL-1, TL-6 and IL-8 activities of the patients with chronic viral hepatic diseases were significantly higher than those of healthy persons (P<0.01). The...

Objective: To observe relationship among cytokine level change in the sera of patients with chronic viral hepatic disease, viral replication and clinical significance. Methods: The TNF-α, IL-1, IL-6 and IL-8 activities in the sera of patients with chronic hepatitis B (CH), chronic severe hepatitis B (CSH) and hepatocirrhosis (HC) by ELISA. Results:The TNF-α, IL-1, TL-6 and IL-8 activities of the patients with chronic viral hepatic diseases were significantly higher than those of healthy persons (P<0.01). The bilirubin level in the sera of patients with chronic viral hepatic disease of different clinical types had a parallel relationship with the cytokine activities. The activites in the sera of HBV-DNA and HBeAg positive patients were significantly higher than those of negative patients (P < 0.01). Conclusion: The patients with chronic viral hepatic diseases had an unbalance on the regultion and control of immunologic function. The activities of cytokine as also as the bilirubin level in the sera of patients can reflect the necrosis degree of liver cells.The cytokine TNF-α, IL-1,IL-6 and IL-8 activities were related to the state of HBV carrier or the active degree of HBV.

目的:为探讨慢性乙型肝炎病毒性肝病患者血清细胞团子TNF-α、IL-1、IL-6、IL-8活性变化及其在慢性肝病发生发展中的作用及临床意义。方法:采用ELISA法对慢性乙型肝炎(CH)、慢性乙型重型肝炎(CSH)、乙型肝炎性肝硬化(HC)患者血清中细胞因子TNF-α、IL-1、IL-6、IL-8活性进行了测定。结果:慢肝患者血清INF-α、IL-1、IL-6、IL-8水平明显高于健康对照组(P<0.01);以上4种细胞因子活性与不同临床类型的慢肝患者血清胆红素含量平行测定二者呈正相关;HBV-DNA或HBeAg阳性患者上述细胞因子活性明显高于HBV-DNA、HBeAg阴性患者(P<0.01)。结论:慢性病毒性肝病患者机体存在免疫功能调控失衡;细胞因子活性与血清胆红素同样可反映肝细胞损伤程度;细胞因子TNF-α、IL-1、IL-6、IL-8活性与患者HBV携带状态即HBV的活跃程度有关。

Objective To observe the clinic therapeutic effect of oxymatrine(OM) combined with promoting hepatocyte growth factor(pHGF) on chronic severe hepatitis B(CSHB). Methods 37 cases with CSHB were randomly divided into two groups:22 cases of treated group and 15 cases of controlled group. They all were treated by comprehensive basic therapy. Treated group was again added to OM 600mg i.m. plus pHGF 200~300mg +10%GS 250~500ml i.v gtt once a day for three months. Results Mortality of treated and controlled group...

Objective To observe the clinic therapeutic effect of oxymatrine(OM) combined with promoting hepatocyte growth factor(pHGF) on chronic severe hepatitis B(CSHB). Methods 37 cases with CSHB were randomly divided into two groups:22 cases of treated group and 15 cases of controlled group. They all were treated by comprehensive basic therapy. Treated group was again added to OM 600mg i.m. plus pHGF 200~300mg +10%GS 250~500ml i.v gtt once a day for three months. Results Mortality of treated and controlled group was 36.4%(8/22) and 73.3(11/15), respectively, P<0.01.In the early and middle stage of CSHB, the mortality of two groups was 10.0%, 57.1% and 42.9%, 80.0%, respectively, P all <0.01. In the later stage, the mortality of two groups was 75% and 100%, respectively, P>0.05. After treatment, the HBsAg of two groups was still positive, while the negative rate of HBeAg and HBV DNA in two groups was 71.4%(10/14), 64.3%(9/14) and 25%(1/4), 0(0/4), respectively, through statistical process,there was a distinct difference (P<0.01) between the two groups. Conclusion In the synthesis treatment, adding to OM combined with pHGF for CSHB, through inhibiting viral replication, promoting hepatocyte growth, obstructing hepatic apoptosis, ect, can decrease the mortality and was well tolerated.

目的 探讨苦参素注射液 (Oxymatrine,OM)联合促肝细胞生长素 (pHGF)治疗慢性乙型重型肝炎 (CSHB)的临床价值。方法 :慢性乙型重型肝炎 3 7例 ,随机分为治疗组 2 2例 ,对照组 1 5例 ,两组均给于综合基础治疗 ,治疗组 2 2例再加用抗病毒药物OM 60 0mg ,肌注 ,每日 1次 ,联合pHGF 2 0 0~ 3 0 0mg +1 0 %GS 2 5 0~ 5 0 0ml中 ,静滴 ,每日一次 ,存活者坚持 3个月一疗程。 结果 治疗组和对照组的病死率分别为 3 6.4% (8/ 2 2 )和 73 .3 % (1 1 / 1 5 ) ,P <0 .0 1 ;在CSHB早、中期二组病死率分别为 1 0 %与 5 7.1 %和42 .9%与 80 % ,P均 <0 .0 1 ,而晚期二组病死率为 75 %与 1 0 0 % ,P >0 .0 5 ;两组治疗后HBsAg均无改变 ,而HBeAg和HBVDNA在治疗组的阴转率为 71 .4% (1 0 / 1 4)和 64 .3 % (9/ 1 4) ,而对照组分别为 2 5 %(1 / 4)和 0 (0 ...

目的 探讨苦参素注射液 (Oxymatrine,OM)联合促肝细胞生长素 (pHGF)治疗慢性乙型重型肝炎 (CSHB)的临床价值。方法 :慢性乙型重型肝炎 3 7例 ,随机分为治疗组 2 2例 ,对照组 1 5例 ,两组均给于综合基础治疗 ,治疗组 2 2例再加用抗病毒药物OM 60 0mg ,肌注 ,每日 1次 ,联合pHGF 2 0 0~ 3 0 0mg +1 0 %GS 2 5 0~ 5 0 0ml中 ,静滴 ,每日一次 ,存活者坚持 3个月一疗程。 结果 治疗组和对照组的病死率分别为 3 6.4% (8/ 2 2 )和 73 .3 % (1 1 / 1 5 ) ,P <0 .0 1 ;在CSHB早、中期二组病死率分别为 1 0 %与 5 7.1 %和42 .9%与 80 % ,P均 <0 .0 1 ,而晚期二组病死率为 75 %与 1 0 0 % ,P >0 .0 5 ;两组治疗后HBsAg均无改变 ,而HBeAg和HBVDNA在治疗组的阴转率为 71 .4% (1 0 / 1 4)和 64 .3 % (9/ 1 4) ,而对照组分别为 2 5 %(1 / 4)和 0 (0 / 4) ,P均 <0 .0 1。 结论 OM联合 pHGF治疗CSHB ,通过抑制乙肝病毒复制、促进肝细胞生长、阻断肝细胞凋亡等作用 ,可降低病死率 ,安全无副反应。

To observe the clinic therapeutic effects of Qxymarine (OM) combined with promoting hepato-cyte growth factor (pHGF) on chronic severe hepatitis B(CSH

目的探讨苦参素注射液(Oxymarine,OM)联合促肝细胞生长素(pHGF)治疗慢性乙型重型肝炎(CSHB)的临床价值。方法慢性乙型重型肝炎37例,随机分为治疗组22例,对照组15例,两组均给予综合基础治疗,治疗组22例再加用抗病毒药物OM 600mg,肌注,1次/d,联合pHGF200~300mg+10%GS250~500ml中,静滴,1次/d,存活者坚持3个月一疗程。结果治疗组和对照组的病死率分别为36.4%(8/22)和73.3%(11/15),P<0.01;在CSHB早、中期二组病死率分别为10%与57.1%和42.9%与80%,P<0.01,而晚期二组病死率为75%与100%,P>0.05;二组治疗后HBsAg均无改变,而HBeAg和HBV DNA在治疗组的阴转率为71.4%(10/14)和64.3%(9/14),而对照组分别为 25%(1/4)和0(0/4),P<0.01。结论OM联合pHGF治疗CSHB,通过抑制乙型肝炎病毒复制、促进肝细胞生长、阻断肝细胞凋亡等作用,可降低病死率,安全无副反应。

 
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