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   泛发型白癜风 的翻译结果: 查询用时:0.69秒
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泛发型白癜风
相关语句
  generalized vitiligo
    Results The allelic frequencies of HLA-A*30, Cw*06, DRB1*07, and DQB1*0201 were increased significantly in generalized vitiligo and especially in the patients without family history compared with the controls.
    结果与正常对照比较,泛发型白癜风患者HLA-A30、Cw06、DRB107、DQB10201基因频率显著增高,其中家族史阴性患者HLA-A30、Cw06、DRB107、DQB10201基因频率显著增高,但家族史阳性患者的等位基因频率差异无统计学意义。
短句来源
    Oxidant-antioxidant enzymes and lipid peroxidation in generalized vitiligo
    泛发型白癜风患者血清氧化剂-抗氧化剂酶与脂质过氧化
短句来源
    Association between HLA-DRB1 and generalized vitiligo in Han people in northern China
    中国北方汉族泛发型白癜风与HLA-DRB1等位基因的相关性
短句来源
    Association of HLA class Ⅰ and Ⅱ alleles with generalized vitiligo in Chinese Hans in north China
    北方汉族泛发型白癜风与HLAⅠ、Ⅱ类等位基因相关性研究
短句来源
    Association of HLA Class Ⅰ and Ⅱ Alleles with Generalized Vitiligo in Chinese Hans in North China
    中国北方汉族泛发型白癜风与HLA-Ⅰ、Ⅱ类基因相关性的研究
短句来源
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  generalized vitiligo
    Results The allelic frequencies of HLA-A*30, Cw*06, DRB1*07, and DQB1*0201 were increased significantly in generalized vitiligo and especially in the patients without family history compared with the controls.
    结果与正常对照比较,泛发型白癜风患者HLA-A30、Cw06、DRB107、DQB10201基因频率显著增高,其中家族史阴性患者HLA-A30、Cw06、DRB107、DQB10201基因频率显著增高,但家族史阳性患者的等位基因频率差异无统计学意义。
短句来源
    Oxidant-antioxidant enzymes and lipid peroxidation in generalized vitiligo
    泛发型白癜风患者血清氧化剂-抗氧化剂酶与脂质过氧化
短句来源
    Association between HLA-DRB1 and generalized vitiligo in Han people in northern China
    中国北方汉族泛发型白癜风与HLA-DRB1等位基因的相关性
短句来源
    Association of HLA class Ⅰ and Ⅱ alleles with generalized vitiligo in Chinese Hans in north China
    北方汉族泛发型白癜风与HLAⅠ、Ⅱ类等位基因相关性研究
短句来源
    Association of HLA Class Ⅰ and Ⅱ Alleles with Generalized Vitiligo in Chinese Hans in North China
    中国北方汉族泛发型白癜风与HLA-Ⅰ、Ⅱ类基因相关性的研究
短句来源
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  “泛发型白癜风”译为未确定词的双语例句
    However,the serum level of selenium from the patients with generacized vitiligo was significantly decreased(P<0 05).
    泛发型白癜风患者血清硒水平降低(P<005);
短句来源
    The sera titers of anti-tyrosinase IgG and IgM antibodies in the universal vitiligo patients was significantly higher than the levels in localized vitiligo patients (P<0.001).
    泛发型白癜风患者血清抗酪氨酸酶IgG、IgM抗体滴度明显高于局限型白癜风患者(均P<0.001)。
短句来源
    ③The average concentration of sICAM-1 in the sera of patients with diffuse vitiligo is(801.40 ng/ml,P<0.001).
    (3)泛发型白癜风患者血清S ICM-1平均水平为801.40 ng/m l,显著高于局限型675.45 ng/m l(P<0.001)。
短句来源
    Results The frequencies of HLA-A*2501,-A*30,-B*13,-B*27 and-Cw*0602 significantly increased in the patients,while the frequency of HLA-A*66 decreased when compared with the controls.
    HLA-A*2501、-A*30、-B*13、-B*27与-Cw*0602等位基因频率在泛发型白癜风患者中显著升高。
短句来源
    An insertion/deletion polymorphism in the gene encoding angiotensin converting enzyme is not associated with generalised vitiligo in an English population
    在英国人群中编码血管紧张素转换酶的基因插入/缺失多态现象与泛发型白癜风无关
短句来源
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  generalized vitiligo
Muscle and skin biopsies confirmed the diagnosis of polymyositis and generalized vitiligo vulgaris.
      
A genomewide screen for generalized vitiligo confirmation of AIS1 on chromosome 1p31 and evidence for additional susceptibility loci.
      
A total of 117 studies on therapies for generalized vitiligo were found.
      
An open trial of adults and children with both segmental and generalized vitiligo were treated with this modality.
      
Figure 4C through Figure 4F also show 2 patients suffering from generalized vitiligo.
      
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The biopsy specimens were collected from 4 patients with nonsegmental type and 4 segmental type of vitiligo and their ultrastructures were observed to investisate the role of Langerhans cells in the pathogenesis of vitiligo. Morphologic changes of Langenhans cells were observed in both types of vitiligo lesions,but these changes were prominently noted in the lesions of patients with segmental type. In lesions of nonsegmental type vitiligo, the morphologic changes of Langerhans calls was very slight. The results...

The biopsy specimens were collected from 4 patients with nonsegmental type and 4 segmental type of vitiligo and their ultrastructures were observed to investisate the role of Langerhans cells in the pathogenesis of vitiligo. Morphologic changes of Langenhans cells were observed in both types of vitiligo lesions,but these changes were prominently noted in the lesions of patients with segmental type. In lesions of nonsegmental type vitiligo, the morphologic changes of Langerhans calls was very slight. The results suggest that Langerhans cells may be involved in lesions of patients with vitiligo. Because these changes were mainly observed in lesions of segmental type of vitiligo, thus, it is hard to define the role of Langerhans calls in the pathogenesis of vitiligo at the present time.

本文对皮节型和泛发型白癜风患者皮肤内郎格罕细胞进行了电镜比较观察。结果表明,两型白癜风患者皮肤内郎格罕细胞均存在着不同程度的形态学改变,以皮节型皮损区更为明显。作者认为白癜风皮肤郎格罕细胞可能受累,但这些改变主要见于皮节型白癜风皮损区。因此目前还难以肯定郎格罕细胞在白癜风发病机制中的作用

In order to study the possible role of selenium in the pathogenesis of vitiligo,We measured the levels of selenium in the sera and the tissue fluids collected by suction blistering from skin lesions and uninvolved skin from 29 eases of vitiligo,using the method of DNA flurophotometry.THe results showed that the serum level of selenium from the patients appeared lowerthan that of normal control group,but the difference was not significant (P<0 05).However,the serum level of selenium from the patients with...

In order to study the possible role of selenium in the pathogenesis of vitiligo,We measured the levels of selenium in the sera and the tissue fluids collected by suction blistering from skin lesions and uninvolved skin from 29 eases of vitiligo,using the method of DNA flurophotometry.THe results showed that the serum level of selenium from the patients appeared lowerthan that of normal control group,but the difference was not significant (P<0 05).However,the serum level of selenium from the patients with generacized vitiligo was significantly decreased(P<0 05).In addition,the level of selenium in the tissue fluid from skin lesions of the patients with vitiligo was significantly lower than that from their uninvolved skin(P<0 05).These results suggest that the pathogenesis of vitiligo might be related to a decreased selenium level,and complement of the element might be heipful in the treatment of the disease.It is noted that selenium may promote the immunologic function of organisms and the pathogenesis of vitiligo is intimately related to immunity.The role of immunity in the pathogenesis of vitiligo in relation to seleium remains a problem to be studied.

为了探讨硒元素与白癜风发病的关系,采用DAN荧光分光光度法,对29例白癜风患者的血清及白斑和无病变部位吸力水疱取材的皮肤组织液中硒含量进行了测定。结果显示:患者组与对照组血清硒含量比较虽有降低,但无显著性差异(P>005);泛发型白癜风患者血清硒水平降低(P<005);患者白斑部位比无病变部位皮肤组织液中硒含量降低(P<005),提示白癜风患者处于缺硒状态,补充硒元素对色素的恢复可能有所裨益,利于缓解病情。硒可增强机体的免疫功能,而白癜风的发病与免疫密切相关,硒元素低下是否通过免疫介导而参与白癜风发病,尚待进一步探讨

Objective The aims were to analyze the clinical characteristics and to explore the potential genetic model of vitiligo in Chinese Han.Methods Information of the clinical feature and the familial history of a large cohort of patients with vitiligo was elicited by a uniform questionnaire.The set of data was analyzed by Epi Info 5.0 and SPSS 10.0 software packages.A complex segregation analysis was conducted using the REGTL program in SAGE 3.1 package in order to propose the putative genetic model of vitiligo.Results...

Objective The aims were to analyze the clinical characteristics and to explore the potential genetic model of vitiligo in Chinese Han.Methods Information of the clinical feature and the familial history of a large cohort of patients with vitiligo was elicited by a uniform questionnaire.The set of data was analyzed by Epi Info 5.0 and SPSS 10.0 software packages.A complex segregation analysis was conducted using the REGTL program in SAGE 3.1 package in order to propose the putative genetic model of vitiligo.Results The mean onset age of vitiligo in the males was about 19 years old,the same to the females. The mean onset age of segmental vitiligo was earlier (P<0.05) than those of the other phenotypes of vitiligo. The prevalence rates of vitiligo among patients’first-and second-degree relatives were significantly higher (P<0.05) than that in the general population. A polygenic additive model was fit for focal vitiligo, acrofacial vitiligo and segmental vitiligo (P>0.05) according to the results obtained by the complex segregation analysis. For universal vitiligo, the best model was an environmental model.Conclusions Males and females are affected by vitiligo with an equal frequency and the same onset age. There is an obvious familial aggregation of vitiligo. This study indicates that different phenotypes of vitiligo have different pathogeneses and genetic backgrounds. Onset of vitiligo is probably determined by both genetic backgrounds and common environmental factors.

目的 探讨中国汉族不同类型白癜风可能的遗传模式。方法 以调查表的形式收集患者的临床资料及家系资料 ,用EpiInfo 5 0及SPSS 10 0软件包进行统计学分析 ,用SAGE 3 1进行遗传模式的复合分离分析。结果 白癜风的平均发病年龄为 19岁左右 ,性别间差异无显著性 (P >0 0 5 ) ;患者一、二级亲属中白癜风患病率较一般人群显著增高 (P <0 0 5 )。局限型、面肢型及节段型白癜风符合多基因累加遗传模式 (P >0 0 5 ) ,泛发型白癜风可能的遗传模式为环境模式 (P >0 0 5 )。结论 白癜风的发生无性别差异 ,但存在明显的家族聚集性 ,不同类型的白癜风发病机制可能不尽相同。该病的发生可能是由多基因累加遗传效应及环境因素共同作用的结果。

 
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