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效应细胞
相关语句
  effector cell
    CD8-positive T cells represent the effector cell population exhibiting antigen specificity for the nucleoprotein.
    CD8~+T细胞代表对核蛋白呈抗原特异性的效应细胞群。
短句来源
    Using the spleen lymphocyte of the immunized mice as the effector cell and P815 cell expressing the structural protein of HIV-1 as the target cell,the specific CTL cytotoxicity activities of spleen lymphocytes in the immunized mice were measured by the method of lactate dehydrogenase(LDH) release assay.
    以免疫小鼠的脾淋巴细胞为效应细胞,以表达HIV- 1结构蛋白的P815细胞为靶细胞,用乳酸脱氢酶释放法测定免疫小鼠脾特异性CTL杀伤活性。
短句来源
    Since macrophages play most important role in bodily defence and inflammatoryresponses, and the activated macrophages release high concentration of PGE, itis postulated that PGE could act locally in cytoprotection to lung cells and in nega-tive feedback inhibition to limit effector cell activities during inflammatory processin lung diseases.
    鉴于巨噬细胞在机体防御和炎症反应中的作用极为重要,而激活巨噬细胞可以释放前列腺素E_1,推论在肺部疾病发展过程中,由激活巨噬细胞释放前列腺素使局部浓度增高时,可以负反馈地调整效应细胞的活力,并对正常肺细胞产生细胞保护作用,以减轻炎症效应细胞对肺组织的伤害。
短句来源
    The results demonstrated that the release of chromium from target cells was an effector cell depended phenomenon and were similar to the CTL activities of mice infected with Hantaan virus.
    CTL活性检测结果表明 :靶细胞51Cr的释放是效应细胞依赖性的 ,并且与病毒感染组的淋巴细胞的细胞毒活性相似。
短句来源
  effective cells
    Killer cells including natural killer cells( NK) and cytotoxic T lymphocyte (CTL) areimportant effective cells in GVHD development. Killer cell inhibitory receptors(KIR) expressed on NK and T cells are the key moleculars in immunity cytotoxicity regulation.
    杀伤细胞(包括NK细胞和细胞毒性T细胞)是参与GVHD发生的重要效应细胞,而其细胞内的杀伤细胞抑制性受体(Killer cell inhibitory receptors,KIR)是调节其免疫杀伤活性的关键分子。
短句来源
    Results The effective cells induced by different stimulator cells could effectively lyse the target cells from the stimulators. Further cell clone study proved that the cytotoxic activity of the effective cells was caused by CD8 + cytotoxic T lymphocytes (CTL).
    结果 用不同刺激细胞诱导产生的效应细胞能有效杀伤刺激细胞来源的靶细胞 ,进一步克隆实验证实这种杀伤效应是由CD8+细胞毒性T淋巴细胞 (CTL)所致。
短句来源
    The enzymes released from effective cells and target cells are mixed together ,and to identify and quantify them are very difficult.
    细胞毒作用过程中效应细胞也有损伤 ,也有酶释放 ,与靶细胞死伤后释放的酶属于同一类 ,而且混合在一起 ,目前尚无可行的定量分离和鉴别方法。
短句来源
    Methods The Epstein Barr virus transformed B lymphoblastoid cell lines ( EBV LCLs) were used as stimulators to induce the peripheral blood monocytes of allotypes or xenogeneity to effective cells. Then the cytotoxitic activity targeting the target cells from the stimulator cells was measured. The long term mixed lymphocyte cytotoxicity experimental model was established.
    方法 利用EB病毒转化的B淋巴母样细胞系作为刺激细胞 ,诱导同种异体或异种外周血单个核细胞增殖 ,并分化为效应细胞 ,然后检测效应细胞对刺激细胞源靶细胞的杀伤活性 ,建立长期混合淋巴细胞培养 细胞毒实验模型。
短句来源
    CPG motifs, also named Immuno stimulatory sequence, can stimulate a large variety of effective cells, have no immunogens, result in no immune diseases, possess significant practical values and great prospective in treatment and prevention of disease.
    CpG序列又名免疫刺激DNA序列 (ISS) ,可激活多种免疫效应细胞 ,且无免疫原性 ,不会引起自身免疫疾病 ,具有很高的实用价值 ,在疾病的防治研究中有着广阔的应用前景 .
短句来源
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  effect cells
    ATP was found to be spontaneously released from effect cells during culture.
    实验中发现效应细胞在培养过程中细胞内ATP自然释放现象;
短句来源
    The preincubation of effect cells and/or target cells with anti-actin antibody resulted in significant inhibition of the cytotoxicity of TM-TNF-α on HL-60 cell line expressing TNFRⅡ, but had no effect on the cytotoxicity of TM-TNF-α on MCF-7 cell line which expressing mainly TNFRⅠ.
    用抗肌动蛋白抗体封闭效应细胞和 或靶细胞后 ,TM TNF α对主要表达TNFRⅡ的肿瘤细胞HL 6 0的杀伤作用显著下降 ,而对主要表达TNFRⅠ的肿瘤细胞MCF 7则无影响。
短句来源
    Slpeen cells of immuned mice(uninmmuned mice for control)used as effect cells. SP2/0-S and SP2/0-P cells served as target cells or control.
    SP2/0-S细胞与SP2/0-P细胞作为靶细胞,免疫鼠与非免疫鼠的脾细胞为效应细胞,按照不同效/靶比共孵育后以酶标仪检测LDH的释放活性。
短句来源
    NK cell line (NK92) was used as NK effect cells and the porcine aortic endothelial cells line (PED) as targets.
    以人类NK细胞系(NK92)效应细胞,猪内皮细胞系(PED)为靶细胞,检测NK92在静止和流动状态下对PED的黏附作用;
短句来源
    Method: We developed a model for observing SIVmac direct cell-cell transferring including effect cells and target cells. The CD4, CCR5 and rvMIP were marked by their monoclonal antibody and then stained by FITC conjugated second antibody before observing with confocal microscopy in order to investigate the movement of CD4 and CCR5 molecules on target cells' surface and count the cell conjugates induced by SIV and the effects of rvMIP was analyzed.
    方法:构建包含效应细胞和靶细胞的SIV在细胞间直接传播的观察模型,采用CD4、CCR5、His6的单抗标记细胞表面受体和rvMIP,并用荧光二抗分别染色,在激光共聚焦显微镜及透射电子显微镜下观察病毒在细胞间直接传播的情况;
短句来源
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  “效应细胞”译为未确定词的双语例句
    Objective To amphfy enough V7 9 Vδ2 T cells for the adoptive therapy of tumor.
    目的体外以仲丁胺刺激健康人外周血PBMC中Vγ9Vδ2T细胞的增殖,为γδT细胞的过继免疫治疗建立效应细胞制备平台。
短句来源
    Inhibitory and apoptosis roles of immunoeffectcells induced by dendritic cells vaccine on PC3 cells
    树突状细胞疫苗诱导免疫效应细胞对PC3的凋亡和抑制
短句来源
    Objective It was known that NK cells played an important role in liver damage caused by hepatitis B virus(HBV).
    目的 NK细胞的细胞毒作用在乙型肝炎病毒(HBV)诱导的肝损伤中起了重要作用,而某些宿主细胞因子和受体基因在这些免疫细胞上的异常表达,可能增强NK等效应细胞对病毒感染细胞的细胞毒作用而参与重型乙肝(FHB)的发病机制。
短句来源
    However, little is known of the expression and function of PARs on human monocytes and T cells.
    单核细胞和T淋巴细胞是炎征和免疫反应重要的效应细胞,但是PARs在人外周血单核细胞和T细胞上表达及它们分泌的细胞因子上的影响则知之甚少。
短句来源
    OBJECTIVE: To investigate the productive kinetics of cytokines during the infection of negative-gram bacteria and the relation of the infection and apoptosis in the thymus, and to observe the variation of the serum cytokine levels and the effect on immune function when infected in order to explain the role of cytokines in severe infection, damage of organ, as well as the thymocyte apoptosis.
    目的:研究革兰阴性菌感染时,机体效应细胞释放炎性细胞因子的动态变化规律和革兰阴性菌感染与胸腺细胞凋亡的关系,观察细菌感染时血清细胞因子水平的变化及对宿主免疫功能的影响,探讨细胞因子在严重感染及器官损害中的作用和对胸腺细胞凋亡的影响,寻找有效的治疗措施并为临床治疗提供理论依据。
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  effector cell
These therapeutic strategies are designed to stimulate dendritic cell proliferation, promote antigen uptake and processing, stimulate an effector cell response via direct antigen presentation, or target tumor cells via antibody therapy.
      
Results indicate that schistosomes restrict effector cell adhesion through developmental, sexual, and regional differences in adhesive properties.
      
The structural rigidity of the effector cell is an important determinant of these functions.
      
The human lung mast cell is known to be a critical effector cell in the mediation of asthma.
      
Acute graft-versus-host disease (GVHD) conceptually may be divided into three evolutionary stages: allostimulation, effector cell homing to specific tissues, and cellular targeting and injury.
      
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  effective cells
These results indicate the usefulness of neural stem cells as therapeutically effective cells for the treatment of intracranial tumors.
      


Based on the specific cytotoxic effect of the induced CTL,we compared the in vivo inhibition of GVHR with the in vitro cytotoxicity by using (51)~Cr release assay.The experiments indicated that there was a marked inhibition of specific GVHR after incuba- tion of the allogeneic spleen cells with the induced CTL.Treatment of the induced CTL with anti-Thy 1 or anti-Lyt 2 antibodies in the presence of complement could eliminate this effect.These results were consistent with the in vitro findings reported previously....

Based on the specific cytotoxic effect of the induced CTL,we compared the in vivo inhibition of GVHR with the in vitro cytotoxicity by using (51)~Cr release assay.The experiments indicated that there was a marked inhibition of specific GVHR after incuba- tion of the allogeneic spleen cells with the induced CTL.Treatment of the induced CTL with anti-Thy 1 or anti-Lyt 2 antibodies in the presence of complement could eliminate this effect.These results were consistent with the in vitro findings reported previously.

根据诱导培养的 CTL 能特异地杀伤带有原刺激抗原的靶细胞这一特性,我们用体内 GVHR 抑制实验来验证诱导培养的效应细胞的功能,发现经效应细胞处理的小鼠脾细胞引起GVHR 的能力明显降低(此效应同样显示出 H-2特异性,并可被抗 Thy 1或抗 Lyt 2抗体消除,与体外实验结果相一致)。

It was observed that exogenously added prostaglandin E_1(PGE_1) inhibitedthe cytotoxic effect of activated macrophages and eosinophils of guinea pig for lungparenchymal cells, and decreased the spontaneous [~3H] release of lung cells. Also,PGE_1 inhibited the phagocytic ability of alveolar macrophages of guinea pig.There are significant dose-response relationships for the inhibitory effect of PGE_1on inflammatory effector cells and the cytoprotective effect of PGE_1 on lung cells.Since macrophages play most...

It was observed that exogenously added prostaglandin E_1(PGE_1) inhibitedthe cytotoxic effect of activated macrophages and eosinophils of guinea pig for lungparenchymal cells, and decreased the spontaneous [~3H] release of lung cells. Also,PGE_1 inhibited the phagocytic ability of alveolar macrophages of guinea pig.There are significant dose-response relationships for the inhibitory effect of PGE_1on inflammatory effector cells and the cytoprotective effect of PGE_1 on lung cells.Since macrophages play most important role in bodily defence and inflammatoryresponses, and the activated macrophages release high concentration of PGE, itis postulated that PGE could act locally in cytoprotection to lung cells and in nega-tive feedback inhibition to limit effector cell activities during inflammatory processin lung diseases.

本文观察到体外培养下,前列腺素E_1 可降低豚鼠巨噬细胞和嗜酸粒细胞对肺细胞的细胞毒作用,可抑制肺泡巨噬细胞的吞噬活性,并能降低标记肺细胞的自发[~3H]释放量。前列腺素E_1 对炎症效应细胞的抑制作用和对肺细胞的保护作用有显著的剂量-效应关系。鉴于巨噬细胞在机体防御和炎症反应中的作用极为重要,而激活巨噬细胞可以释放前列腺素E_1,推论在肺部疾病发展过程中,由激活巨噬细胞释放前列腺素使局部浓度增高时,可以负反馈地调整效应细胞的活力,并对正常肺细胞产生细胞保护作用,以减轻炎症效应细胞对肺组织的伤害。

The 3H-thymidine target cells (YAC-1, P815, LAC-1, murine lymphoblast) were incubated with effector cells for 4 or 18 hr. The cultured cells were treated with trypsin and DNase. Then the cells were harvested by MASH and detected by liquid scintillator. The results showed that the method discribed in this paper were good for both specific and nonspecific lymphocyte mediated cytotoxicity. The magnitude of the NK activity was varied, depending upon the mouse strain. The spontaneous release of 3H-thymidine was lower...

The 3H-thymidine target cells (YAC-1, P815, LAC-1, murine lymphoblast) were incubated with effector cells for 4 or 18 hr. The cultured cells were treated with trypsin and DNase. Then the cells were harvested by MASH and detected by liquid scintillator. The results showed that the method discribed in this paper were good for both specific and nonspecific lymphocyte mediated cytotoxicity. The magnitude of the NK activity was varied, depending upon the mouse strain. The spontaneous release of 3H-thymidine was lower (less than 10%) and the specific cytotoxic release was higher than the release of 51Cr.

本文用 ~3H-胸腺嘧啶核苷(~3H-TdR)标记多种靶细胞(YAC-1、P815、LAC-1、小鼠淋巴母细胞)与不同效应细胞培养4或18小时,再用胰酶和DNA 酶处理靶细胞,收集细胞,用液体闪烁微杯法测定小鼠特异性和非特异性淋巴细胞介导的细胞毒试验,均获得良好结果。与~(51)Cr释放相比,~3H-TdR 方法具有自然释放率低(<10%),特异性释放率高的特点。

 
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