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Traditional Chinese medicine suggests that senile constipation may occur under such conditions: 阴阳失调 Yini-yang Shitiao (Yin-yang imbalance), 气血虚弱 Qixue Xuruo (weakness of vitality and blood) and 脏腑功能衰退 Zanfu Gongneng Shuaitui (functional degradation of internal viseral organs), which cause insufficiency of intestinal passage and deficicency of secretion of body fluids. Basing on the traditional theories of 八纲辩证 Bagan Bianzheng (analysis and differentiation of pathologic condition in coordination with the 8 principal...

Traditional Chinese medicine suggests that senile constipation may occur under such conditions: 阴阳失调 Yini-yang Shitiao (Yin-yang imbalance), 气血虚弱 Qixue Xuruo (weakness of vitality and blood) and 脏腑功能衰退 Zanfu Gongneng Shuaitui (functional degradation of internal viseral organs), which cause insufficiency of intestinal passage and deficicency of secretion of body fluids. Basing on the traditional theories of 八纲辩证 Bagan Bianzheng (analysis and differentiation of pathologic condition in coordination with the 8 principal syndromes), and 脏腑辩证 Zangfu Bianzheng (analysis and differentiation of pathologic conditions in accordance with internal organs), the senile constipation is classifiedinto 4 types: a. 肾水不足便秘 Shengshui Buzu constipation caused by renal fluid insufficiency and treated by 滋阴生肾水 Ziyin Shengshenshui methed (nourishing Yin and increased renal fluids using 六味地黄丸 Rhenia glutinosae pill; b. 气阴两虚便秘 Qiyie Liangxu constipation caused by deficiency of both vitality and Yin) and 润肺能便 Runfei Tungbian (moisten the lung and free bowel movement) using 加味生脉散 Jiawei Shengmei powder (additional drugs to promote the blood circulation by invigorating vital energy;c. 中气不足便秘 Zhongqi Buzu constipation caused by deficiency of vitality and treated by 调补脾胃 Tiaobu Piwei (reinforce the stomach and bowels) and 益气升阳 Yiqi Shengyang (reinforce vitality and increase Yang) using 补中益气汤 Buzhong Yiqi decoction (drugs to nurish the midtorso and reinforce vitality) and d. 脏寒便秘 Zanghan constipation caused by coldness of internal viseral organs and treated by 温肾逐寒 Wenshen Znuhan (warm the Kidney and expel coldness) and 通阳泻浊 Tongyan Xiezu (clear Yang passage and expel the foul excretion) using 加味半硫 Jiawei Baliu pill (semi-sulfur adding other herbal drugs).

中医学认为,老年便秘是由于阴阳失调,气血虚弱,脏腑功能衰退而导致大肠传导不利,津液不足之故。笔者根据八纲辨证和脏腑辨证等原则,将老年便秘分为肾水不足便秘,治以滋阴生肾水为法,六味地黄丸为代表方;气阴两虚便秘,治以益气养阴,润肺通便为法,加味生脉散为代表方;中气不走便秘,治以调补脾胃,益气升阳为法,补中益气汤为代表方;脏寒便秘,治以温肾逐寒,通阳泻浊为法,加味半硫丸为代表方。

Peripheral blood lymphocytes(PBL)of rat stimulated with con-A and PHA were cultured respectively on rat cryostat kidney section.After 24 hours,the glomeruIar polyanion(GPA)was studied with the colloidal iron (CI)stain.The results show that lymphocyte of rat induced with con-A are able to reduce GPA stainabitity,whereas lymphocytes induced by PHA, unlnduced lymphocytes,moaoauclear Cells induced with con-A and su- pernate of lymphocytes induced with con-A were not able to reduce GPA stainability.Meanwhile it was...

Peripheral blood lymphocytes(PBL)of rat stimulated with con-A and PHA were cultured respectively on rat cryostat kidney section.After 24 hours,the glomeruIar polyanion(GPA)was studied with the colloidal iron (CI)stain.The results show that lymphocyte of rat induced with con-A are able to reduce GPA stainabitity,whereas lymphocytes induced by PHA, unlnduced lymphocytes,moaoauclear Cells induced with con-A and su- pernate of lymphocytes induced with con-A were not able to reduce GPA stainability.Meanwhile it was shown that lymphocytes of rat induced with con-A for 24 hours were able to suppress invitrolymphocyte transformation of syngeneic PBL in a co-culture system following the con-A or PHA sti- mulation.The results were similar to those of the pathological injury of human minimal change nephrotic syndrom(MCNS).It is suggested that pa- thological injury of MCNS be possibly due to the suppression of cells which affects glomerular basement membrane by releasing either a unstable me- diator in Short range or cell direct contact.

将大白鼠的外周血淋巴细胞分别用 Con-A 和 PHA 刺激;并分别与大白鼠低温肾切片共同孵育24h 后,用胶性铁染色检查肾小球多阴离子(GPA)。发现 Con-A 诱导的鼠淋巴细胞能减少 GPA 的染色能力,而 PHA 诱导的淋巴细胞,未经诱导的淋巴细胞、Con-A 诱导的单核细胞和 Con-A 诱导的淋巴细胞上清均无此作用。此结果与人类微小病变型肾病综合征的病理损伤有相似之处。

The author reports that in the experiment mice are divided into three group: the Kid—ney—yang deficiency group, the Kidney—yang deficiency and warm Kidney—yang group, and the control group. The bioelectrical waves from the internal ear in the first group are abnormal, with a lower vibrative range, a higher hearing threshold, and a shorter duration of electropotential. The condition of the second group is obviously betterin the above indexes, which reveals a marked difference between the two groups. The result...

The author reports that in the experiment mice are divided into three group: the Kid—ney—yang deficiency group, the Kidney—yang deficiency and warm Kidney—yang group, and the control group. The bioelectrical waves from the internal ear in the first group are abnormal, with a lower vibrative range, a higher hearing threshold, and a shorter duration of electropotential. The condition of the second group is obviously betterin the above indexes, which reveals a marked difference between the two groups. The result shows that the function of the internal ear is damaged in the mice with Kidney— yang deficiency and the method of warming and promoting Kidney—yang can effect improvement. This proves the theory that "the kidney has the ears as its opening" has an underlying basis.

本文报道了在建立豚鼠肾阳虚动物模型的基础上,将实验动物分为三组:肾阳虚组、肾阳虚+温肾组和正常对照组。实验中观察到,肾阳虚动物的内耳生物电波型异常,振幅降低,听阈升高,电位持续时间缩短;而温肾组上述指标均有不同程度改善,与肾阳虚组相比有显著性差异。说明肾阳虚状况下的动物内耳功能受到损害,温补肾阳可促使其改善,提示中医“肾开窍于耳”的理论是有其内在基础的。

 
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