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   惊厥阈值 的翻译结果: 查询用时:1.251秒
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惊厥阈值     
相关语句
  seizure threshold
     The Influence of Scopolamine on the Seizure Threshold Seizure Behavior and Neuronal Transmitter in Rats
     东莨菪碱对实验性大鼠惊厥阈值、惊厥行为及脑内部分神经递质的影响
短句来源
     In the first part, we use direct cortical stimulation animal model, to observe the influence of scopolamine on the seizure threshold and neuronal protective effects in hippocampus.
     第一部分采用直接电刺激大鼠皮层惊厥阈值测定模型作为研究对象,动态观察东莨菪碱对于癫痫大鼠惊厥阈值,后放发作行为的影响,以及对海马部位神经元的保护作用。
短句来源
  convulsion threshold
     ②While both of midazolam and diazepam elevated the convulsion threshold in rats(P<0.05),the effect of former was more quickly and effectively.
     ②咪达唑仑、地西泮均能显著提高模型大鼠的惊厥阈值(P<0.05),但前者抗惊厥效应更强,能更快发挥作用;
短句来源
     Results:Convulsion threshold of Datarametel L group was increased after administration, and was significantly higher than that of control group (P<0.05). The longer time after administration, the higher of convulsion threshold of Datarametel L group was compared with that before using it (P<0.05). But the anticonvuIsant effect of Datarametel L was lower than that of Carbamazepine.
     结果 :洋金花组在给药后癫痫大鼠惊厥阈值明显增高 ,与对照组比较有统计学意义 (P <0 .0 5 ) ,随用药时间延长 ,其惊厥阈值与用药前比较亦渐升高 (P <0 .0 5 ) ,但其抗惊厥作用较卡马西平弱。
短句来源
  convulsive threshold
     It was reduced to 950 μA at 12 hrs after administration. The convulsive threshold of the SMV and the DC groups peaked at 7 hrs after single administration (1085 and 1023 μA respectively ), which were noticeably higher than that of the controls (P<0.05).
     丙戊酸镁缓释片及德巴金给药后7h左右达峰,惊厥阈值分别升高至1085μA及1000μA,显著高于对照组(P<0.05),给药后12h两组惊厥阈值均保持在1023μA左右。
短句来源
     After one month of repeated administration, the kidney and the liver of the rats were removed for pathological examinations. Results the convulsive threshold of the MV group reached to a peak (1100 μA) at 1-2 hrs after single administration, which were significantly higher than that of the other three groups (P<0.05), and began to decrease 3 hrs after administration.
     结果对照组24h内惊厥阈值稳定在860±40μA,丙戊酸镁单次给药后1~2h达药效高峰,大鼠惊厥阈值升高至1100μA,较其它三组明显升高(P<0.05),给药后3h其药效开始下降,至12h其惊厥阈值下降至950μA。
短句来源
     After repeated administration for 10 times,the convulsive threshold of the SMV group increased by 430 μA and that of the DC group increased by 230 μA.
     重复给药过程中丙戊酸镁组的惊厥阈值的峰谷平均差值为120~150μA,是丙戊酸镁缓释片和德巴金峰谷差值的2倍和2.5倍。
短句来源
     The average peak valley deviation of the convulsive threshold in the MV group was 120-150 μA, which was two times as the SMV group and 2.5 times as the DC group after repeated administration.
     重复给药10次后,丙戊酸镁缓释片组惊厥阈值较给药前升高430μA,德巴金缓释片组升高230μA。
短句来源
     Methods The model of determining the convulsive threshold was prepared by direct cortical stimulation. Eighty model rats were randomly received intragastric administration of MV, SMV, DC or normal saline (controls).
     方法利用大鼠抗电刺激皮层惊厥阈值模型,观察三种药物组及假阳性对照组单次及重复给药后大鼠惊厥阈值动态变化趋势,连续给药一个月后取其肝肾做病理学检查。
短句来源
更多       
  convulsant threshold
     Results:Copampared with control group, Propofol as well as thioptentone increased convulsant threshold of mice in a dose dependent manner ( P <0.01).
     相同镇静剂量的异丙酚与硫喷妥钠比较 ,异丙酚升高小鼠荷包牡丹碱惊厥阈值的作用强于硫喷妥钠 (P <0 .0 5 ) ,而异丙酚对小鼠印防己毒素惊厥阈值的作用弱于硫喷妥钠 (P <0 .0 5 )。
短句来源
     Results Flos daturae receiving group got a markedly higher convulsant threshold compared with the control group,with a statistical difference(P<0.05),however flos daturae's anticonvulsant effect was weaker than the CPZ's.
     结果洋金花组在给药后大鼠惊厥阈值明显增高,与对照组比较,差异有统计学意义(P<0.05),但其抗惊厥作用较卡马西平为差。
短句来源
     (2) We used the threshold for localized seizureby direct cortical stimulation model to observe the influence of Midazolam andDiazepam on convulsant threshold by rectum in few minutes and study theirchanges of seasoning and effect.
     (2) 实验采取直接电刺激大鼠皮层惊厥模型作为观察对象,动态观察咪达唑仑、地西泮直肠给药几分钟内对模型惊厥阈值的影响,研究其时效和药效的变化;
短句来源
     Flos daturae to influence rat's electrostimulus-induced cerebral cortex convulsant threshold and its hippocampal neuron morphosis
     洋金花对电刺激大鼠皮层惊厥阈值及海马神经元形态结构的影响
短句来源
     Objective Observing flos daturae's influence on rat's cerebral cortex convulsant threshold to find out whether flos daturae(FD) has any protective action to the morphosis of epileptic rat's hippocampal neuron.
     目的观察洋金花对癫痫大鼠皮层惊厥阈值的影响及对癫痫大鼠海马神经元形态结构是否有保护作用。
短句来源
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      seizure threshold
    Some potentia lcompounds were also tested in the subcutaneous strychnine (scSTY) and subcutaneous picrotoxin (scPIC) seizure threshold tests.
          
    At least four high-frequency repetitive stimuli of high intensity may thus be applied with a low risk of seizure induction even in patients with low seizure threshold.
          
    When interictal psychosis persists despite such adjustments, initiation with low-dose atypical antipsychotics carries the least risk of lowering seizure threshold and should be considered.
          
    Endogenous neuropeptide Y prevents recurrence of experimental febrile seizures by increasing seizure threshold
          
    Single perfusions of latrunculin A and jasplakinolide decrease and increase picrotoxin seizure threshold, respectively.
          
    更多          
      convulsion threshold
    These effects were response and dosage dependent, with the greatest enhancement of performance occurring at dosages just under the convulsion threshold.
          
    YM-14673 antagonized reserpine-induced hypothermia and decrease in convulsion threshold in mice.
          
    Twenty-four and forty-eight hours after the last injection measurements were made of the effects on convulsion threshold, body temperature and locomotor activity, of drugs acting on the GABA receptor complex.
          
    The KM rats showed neither catalepsy nor a rise in the generalized convulsion threshold, and the depression of the motor cortex excitability in them was only slight.
          
    Animals were able to tolerate camphor at doses 3/2-3 times convulsion threshold level without seizure occurring once habituation to the action of this convulsant had been developed.
          
      convulsive threshold
    The decrease of convulsive threshold, often revealed only by means of the EEG, appears to be a therapeutic principle in every kind of psychiatric somatotherapy.
          
    The effect of withdrawal from cannabis on pentylenetetrazol convulsive threshold in mice
          
    There was no significant difference from controls in the convulsive threshold of mice which had received cannabis extract at any of the doses employed when tested 6 hrs, 16 hrs, 1, 3 or 6 days after medication had been withdrawn.
          
    From these findings, the convulsive threshold for TCP during B withdrawal proved well correlated to the grade of B-dependence and the duration of B-withdrawal signs.
          
    Reduction of flurazepam convulsive threshold by Ro 15-1788
          
    更多          
      convulsant threshold
    A single withdrawal from diazepam following chronic treatment gave rise, 72?h following the last dosing, to behavioural changes, suggestive of anxiety, in both tests, but did not result in a reduced convulsant threshold.
          


    Here we utilized genetically epilepsy-prone rats (P77PMC) matched with epilepsyresistant Wistar rats to investigate the changes in the gene expression of NR1 subunit of NMDA receptor in different brain regions during development. Methods: Northern blot hybridization. Results: NR1gene expression in cerebral cortex, hippocampus, in ferior colliculus reached a peak at approximately 2~4 weeks after birth and the NR1 mRNA expression of P77PMC rat was higher than that of control during that period. Conclusion: The...

    Here we utilized genetically epilepsy-prone rats (P77PMC) matched with epilepsyresistant Wistar rats to investigate the changes in the gene expression of NR1 subunit of NMDA receptor in different brain regions during development. Methods: Northern blot hybridization. Results: NR1gene expression in cerebral cortex, hippocampus, in ferior colliculus reached a peak at approximately 2~4 weeks after birth and the NR1 mRNA expression of P77PMC rat was higher than that of control during that period. Conclusion: The increased expression of NR1 mRNA in P77PMC during developmentmay be one of the factors associated with susceptibility of epilepsy.

    目的:比较发育中遗传性癫痫易感大鼠P77PMC和癫痫不易感大鼠Wistar不同脑区NMDA受体(N-methyl-D-aspartatereceptor,NR)一型亚基(NR1)基因表达特点,探讨其与惊厥易感性的关系。方法:Northern印迹杂交方法。结果:两系大鼠发育中,大脑皮层、海马、下丘3个脑区NR1mRNA表达趋势一致,并有共同规律,即出生后表达量逐渐增加,在发育的某一阶段到高峰,成年下降并稳定于某一水平,在整个发育过程中,P77PMC大鼠NR1mRNA的表达量高于Wistar大鼠,并在某一阶段显著增高。结论:提示发育中P77PMC大鼠脑内NR1亚基基因表达增高可能是造成P77PMC大鼠“低惊厥阈值”及对听源性惊厥易感的原因之一。

    We haVe studied the anticonvulsant effect of Chai Hu in freely rast using the method of the frontal cortical threshold test by direct cortical stimulation. The apriment shows that the anticonvalsant effect of Chai Hu has its dose - effect relation . Compared to antiepileptic drug valium , its dose is 10 times larger than that of valium .Its change of threshold attains the maximal amount (23l ±112.53μA, mean± sd) after three hours of injection.Ths increase is significant (P <0.05), and the effect still...

    We haVe studied the anticonvulsant effect of Chai Hu in freely rast using the method of the frontal cortical threshold test by direct cortical stimulation. The apriment shows that the anticonvalsant effect of Chai Hu has its dose - effect relation . Compared to antiepileptic drug valium , its dose is 10 times larger than that of valium .Its change of threshold attains the maximal amount (23l ±112.53μA, mean± sd) after three hours of injection.Ths increase is significant (P <0.05), and the effect still remains after 6hours . The experiment also shows tha Chai Hu has not poisonous side effect.

    采用测定大鼠额叶皮层电惊厥阈值作为指标的方法,观察柴胡的抗惊厥作用,发现柴胡的抗惊厥作用具有一定的量效关系,与抗惊厥西药安定比较,剂量较大,约为安定剂量的10倍,注射后3小时,阈值增加达最大值(231±112.52μA,均数±标准差),具有统计学意义(P<0.05),6个小时后,这种意义依然存在,而且实验表明柴胡无明显的毒副作用。

    The anticonvulsant effect of extracts of traditional Chinese herbal medicines have been tested in freely moving rats by deter- mination of threshold for localized seizures by means of direct cordeal stimulation via chronically implanted electrodes.Extracts of Euphorbia fischeriana,Rhizoma Arisaematis and Radix Ampelopis were administered intraperitoneally in a single dose of 10 mg/ kg.A control group received normal saline injection.The maximal increase in threshold compared to baseline values were 93± 29 uA(mean±SD),n=6)for...

    The anticonvulsant effect of extracts of traditional Chinese herbal medicines have been tested in freely moving rats by deter- mination of threshold for localized seizures by means of direct cordeal stimulation via chronically implanted electrodes.Extracts of Euphorbia fischeriana,Rhizoma Arisaematis and Radix Ampelopis were administered intraperitoneally in a single dose of 10 mg/ kg.A control group received normal saline injection.The maximal increase in threshold compared to baseline values were 93± 29 uA(mean±SD),n=6)for Euphorbia fischeriana,119±22 uA for Rhizoma Arisaematis and 83±19uA for Radix Ampelop- is.These increases were significant(P<0.01).Within 1 hour of the injection,the effect reached a plateau level which lasted 3 days for Radix Ampelopis,5 days for Rhizoma,na Arisaematis and 7 days for Euphorbia fischeriana.Apart from a slight sedative effect on the day of injection,no other side effects were observed.In the convulsion induced by pentylene-tetrazol incubation pe- riod of control group,Euphorvia fischeriana group,Rhizoma Arisarmafis group and Radix Ampelopis group were 3.5 min,7.5 min,7.4 min and 6.8 min,respectively.The results showed that the extracts of these three medicines exhibited not only dis- tinct effect on convulsive threshold,but also long duration of action.

    采用自动惊厥测定仪测定狼毒大戟、天南星、白蔹提取物的抗电刺激皮层惊厥阈值和抗戊四唑惊厥作用的结果。3种中药提取物以10ml/kg(相当于原生药1.2g/kg)腹腔注射。结果:给药后狼毒大戟组惊厥阈值提高(118±29)μA,效果持续10天;天南星组提高(119±22)μA,效果持续7天;白蔹组提高(83±19)μA,效果持续5天。抗戊四唑惊厥实验:对照组的惊厥潜伏期为3.5min,狠毒大戟为7.5min,天南星为7.4min,白蔹为6.8min。除给药当天动物有轻度镇静作用外,未见其他毒副作用。实验结果提示3种药提取物不但有明显的抗惊厥作用(P<0.001),而且药效持续较久。

     
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