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肾小球上皮细胞
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  glomerular epithelial cell
     Effect of interleukin-2 on the biologicalfunction of glomerular epithelial cell in vit-ro
     白细胞介素-2对肾小球上皮细胞部分生物学功能的影响
短句来源
     4days after McAb F2 was injected into SD rats by vein,immunohistochemical and immunoelectron microscopy showed that McAb F2 could recognize and bind to the antigen on the surface of the glomerular epithelial cell,and form typical immune complexes of PHN in vivo.
     Western-Blot分析显示,McAbF2识别天然膜抗原Fx1A中分子量为44KDa的受体相关蛋白(Receptor-asociatedprotein,RAP),SD大鼠体内注射McAbF24天后肾皮质免疫组化和免疫电镜发现McAbF2在体内能识别肾小球上皮细胞表面抗原,并与之结合形成典型的PHN免疫复合物。
短句来源
     Effects of lipopolysaccharide (LPS), protamine sulfate (PS) and Bushenhuoxuexiezhuo Decoction (BD) on the syntheses of protein and heparin sulfate proteoglycan (HSPG) were studied in the cultured glomerular epithelial cell (GEC) of rat, by serum pharmacological method.
     探讨脂多糖 (LPS)、硫酸鱼精蛋白及补肾活血泄浊汤对体外培养大鼠肾小球上皮细胞(GEC)蛋白质和硫酸肝素蛋白多糖 (HSPG)合成的影响。 应用LPS、硫酸鱼精蛋白作为刺激因子 ,观察其对GEC蛋白质和HSPG合成的影响 ;
短句来源
     Effects of Bushenhuoxuexiezhuo Decoction on Syntheses of Protein and Heparin Sulfate Proteoglycan in the Cultured Glomerular Epithelial Cell of Rat
     补肾活血泄浊汤对肾小球上皮细胞蛋白质和硫酸肝素蛋白多糖合成的影响
短句来源
     The effect of immune cell from nephrotic children on the matrix synthesis of glomerular epithelial cell
     肾病患儿免疫细胞对肾小球上皮细胞合成基质的影响
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  “肾小球上皮细胞”译为未确定词的双语例句
     The numbers of anionic sites was not changed in L-NNA+I-RI group(14.7±0.9/(1 000 nm),P>0.05).
     L-NNA+I-R I组大鼠肾小球上皮细胞足突融合也明显加重,但和I-R I组相比,L-NNA+I-R I组大鼠GBM的AS数量[(14.7±0.9)个/1 000 nm]无显著差异(P>0.05)。
短句来源
     The expression of TGF β 1 significantly increased and it was mainly localized in proximal tubular cells.
     TGF β1蛋白的表达增高 ,大部分近曲小管、少数肾小球上皮细胞、系膜细胞和极少数的远曲小管可见TGF β1蛋白的强阳性表达。
短句来源
     Conclusions TGF β1 may stimulate the glomerular epithelial cells to secret excessive amounts of extracellular matrix and mediate the development of AHN.
     结论 TGF β1可能通过刺激主动型Heymann肾炎大鼠肾小球上皮细胞产生过量细胞外基质 ,从而介导了主动型Heymann肾炎病变的发生和发展
短句来源
     Results Supplementing Qi and nourishing Yin,clearing and promoting blood circulation traditional Chinese drug could decrease the excretion quantity of urine protein in minimal change nephropathy rats,improve serum biochemical indicator,lower TXB_2 level in plasma and urine,raise 6-keto-PGF 1α level in urine,improve hypercoagulabale state and repair glomerule epithelial cell foot process structure.
     结果益气养阴、清利活血中药可减少微小病变肾病大鼠尿蛋白的排泄量,改善血清生化指标,降低血浆、尿液TXB2水平,提高尿液6-keto-PGF 1α水平,改善高凝状态,修复肾小球上皮细胞足突的结构。
短句来源
     Results:The drugs of Yi-Qi Yang-Yin and Qing-Li Huo-Xue can decrease the amount of protein in urine,promote the level of ALB and lower the CHOL,TG,IL-8,TNF-α in serum,repair injured foot process of glomerule epithelial cell.
     结果 :益气养阴、清利活血中药可减少阿霉素肾病大鼠尿蛋白的排泄量 ,提高血清ALB含量 ,降低血清TG、CHOL、IL 8、TNF α的含量 ,修复肾小球上皮细胞足突的结构。
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  相似匹配句对
     Effect of epidermal growth factor on glomerular epithelial cells cytoskeleton
     表皮生长因子对肾小球上皮细胞骨架的影响
短句来源
     vacuolar degeneration in the renal tubular epithelium and the liver cells;
     肾小管上皮细胞空泡变性,肾小球萎缩;
短句来源
     Microvascular Architecture of Human Fetal Renal Glomerulus A SEM Study of Vascular Casts
     胎儿肾小球血管构筑
短句来源
     glomerulus and tubules.
     引起肾小球的损伤;
短句来源
     Haemorrhages in stomach, its epithelial cells were necrosis and fell away.
     胃出血,上皮细胞脱落;
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  glomerular epithelial cell
Width of glomerular epithelial cell foot processes and of filtration slits were determined by morphometric methods in 11 non-diabetic kidney donors and in 28 diabetic patients with albumin excretion rates ranging from normal to proteinuria.
      
A primary glomerular culture and a glomerular epithelial cell culture were made; supernatant from monocyte cultures derived from healthy humans, and recombinant tumour necrosis factor α (TNF α) or recombinant interleukin 1 β (IL-1 β) were added.
      
A primary glomerular culture and a glomerular epithelial cell culture were made; supernatant from monocyte cultures derived from healthy humans, and recombinant tumour necrosis factor α (TNF α) or recombinant interleukin 1 β (IL-1 β) were added.
      
CD68-positive cells were minor components of cellular crescents, indicating that the major principal cellular component of the crescents is made up of cells with the parietal glomerular epithelial cell (PEC) phenotype.
      
The peripolar cell is a glomerular epithelial cell situated within Bowman's capsule at its vascular pole.
      
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An EHF pregnant woman delivered a premature infant with the rather typical EHF changes. Anti-EHF-IgG was found both in the blood of the mother and the umbilical cord and in the heart of the infant. EHF antigens were detected positively with the labelled and unlabelied monoclonal antibodies by the direct fluorescent staining, and ABC and PAP immunohistochemical methods.The infiltration of macrophages in the interstitial tissues of the kidney, lung, placenta and umbilical cord was accompanied with a moderate inflammatory...

An EHF pregnant woman delivered a premature infant with the rather typical EHF changes. Anti-EHF-IgG was found both in the blood of the mother and the umbilical cord and in the heart of the infant. EHF antigens were detected positively with the labelled and unlabelied monoclonal antibodies by the direct fluorescent staining, and ABC and PAP immunohistochemical methods.The infiltration of macrophages in the interstitial tissues of the kidney, lung, placenta and umbilical cord was accompanied with a moderate inflammatory reaction.These results suggested that the transmission of the disease from a mother to an infant was through the placenta and the dissemination of the disease via the macrophage system.

妊娠6~+个月孕妇感染流行性出血热(EHF),临床有典型的EHF的发病过程。第23病日血清学检测孕妇外周血EHF-IgG(卅)、IgM(-),第24病日流产一女婴,抽取脐带血检测EHF-IgG(卅),流产女婴心血检测EHF-IgG(卅),IgM(-)。病理:肾小球上皮细胞肿胀,上皮细胞足突融合、坏死,毛细血管基底膜皱缩,肾小管上皮细胞线粒体肥大,间质内大单核细胞浸润。肺间质细胞增生、水肿、毛细血管基底膜不规则增厚,肺泡壁Ⅱ型细胞增多。肝细胞肿胀,胞浆内查见包涵体样物质,有多核肝巨细胞,地依红染色阴性。胎盘母体面、脐带、肺、肝间质内大单核细胞、中性粒细胞浸润。EHF-MCAb荧光直接法染色、PAP、ABC等免疫组化染色,在巨噬细胞浆内均为阳性反应,从而证实母体感染EHF可以经胎盘感染给胎儿,其传播方式可能是通过巨噬细胞系统。

23 male mongrel grey rabbits received gcntamicin sulfate 150 mg/kg daiiy by intramuscular injection for 7 consecutive days. 3 animals were killed every day. The proximal tubular celis of kidney showed cloudy swelling, granular and lipoid dcgcneration during 1-4 days by light microscopy, but from 5 to 7 days focus and diffuse proximal tubular necrosis appcared. Electron microscopy: Organelle of proximal tubular celis showed alteration, primary and secondary lysosomes increased, many myiloid bodies were present,...

23 male mongrel grey rabbits received gcntamicin sulfate 150 mg/kg daiiy by intramuscular injection for 7 consecutive days. 3 animals were killed every day. The proximal tubular celis of kidney showed cloudy swelling, granular and lipoid dcgcneration during 1-4 days by light microscopy, but from 5 to 7 days focus and diffuse proximal tubular necrosis appcared. Electron microscopy: Organelle of proximal tubular celis showed alteration, primary and secondary lysosomes increased, many myiloid bodies were present, and some celis showed necrosis. Thcse lesions were found severe on the 4 th day and became more severe day by day. These lesions could also be seen in the epithelial and endothelial celis of glomerulus with foot process fusion. The formation of these lesions is due to accumulation of gentamicin in lysosome, and as a result, phospholipase and sphingomyelinase are inhibited, and phospholipidosis is induccd. Acquircd lysosomal storage disorders are thus formed.

用雄性杂种灰兔每天一次肌肉注射硫酸庆大霉素150mg/kg,每天杀检3只共7天。电镜下可见近端肾小管上皮细胞的细胞器肿胀、变性,溶酶体增多伴有髓样小体形成,乃至细胞崩解坏死,肾小球上皮细胞和内皮细胞也有类似病变。主要由于庆大霉素沉积于溶酶体内,使磷脂酶受到抑制造成,为继发性溶酶体贮积病。

A single intravenous injection of ad-riamycin (5mg/ kg) into rats causedthe full expression of nephrotic syndromecharacterized by heavy proteinuria, hy-poalbuminemia, hypercholesterolemia,thoracic and ascitic fluid, swelling andfusion of foot processes of epithelial cellscould be observed under electron micro-scope;histologic examination by light mi-croscopy did not reveal any significantchanges. The features of the model in cli-nic and pathology were very similar tothose described humans with minimalchange...

A single intravenous injection of ad-riamycin (5mg/ kg) into rats causedthe full expression of nephrotic syndromecharacterized by heavy proteinuria, hy-poalbuminemia, hypercholesterolemia,thoracic and ascitic fluid, swelling andfusion of foot processes of epithelial cellscould be observed under electron micro-scope;histologic examination by light mi-croscopy did not reveal any significantchanges. The features of the model in cli-nic and pathology were very similar tothose described humans with minimalchange nephrotic sydrome. The observa-ation in the various periods of the modelindicated that the ultrastructure changesin epithelial cells occurred prior to theonset of proteinuria. The present study,combined with the results of quantitativeanalysis with image analyzer for altera-tion of glomerular polyanions. suggeststhat both morphologic changes and pro-teinuria may be the consequence of acommon primary event that is the loss ofglomerular polyanions. The model has theadvantages of being rather simple ndconvenient;providing lasting proteinuriaand pathological changes in stable condi-tion; and having high reproducibility anda sufficient suppy of the drug used.

作者用阿霉素(5mg/kg)给大鼠一次性静脉注射,造成功极似人类微小病变型肾病综合征的动物肾病模型,表现为严重蛋白尿、低白蛋白血症、高胆固醇血症及胸、腹腔积液;电镜下肾小球上皮细胞足突肿胀、融合,光镜下病变甚微;上皮细胞足突肿胀、融合先于白蛋尿出现。结合以前所作肾小球多阴离子定量分析的结果,认为多阴离子的丢失系上皮细胞足突肿胀、融合和白蛋尿产生的主要因素。该模型具有方法简便,蛋白尿持续时间长,病变稳定,药源充足,制作成功率高等优点。

 
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