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病理     
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  pathology
    The Study of Clinical Features, Pathology, Emerin and the Expression of STA Gene in Patients with Emery-Dreifuss Muscular Dystrophy
    Emery-Dreifuss型肌营养不良症的临床、病理、emerin蛋白及STA基因表达的研究
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    Study on the Clinic, Pathology, Epidemiology of HSLE and the Cytochrome P4502D6 Genetic Polymorphism with the Susceptibility of HSLE
    海洛因海绵状白质脑病的临床、病理、流行病学调查和CYP4502D6基因多态性关系的研究
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    Study on CT Perfusion Imaging and Pathology of Rat C6 Glioma Model
    大鼠C6胶质瘤的CT灌注和病理对照研究
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    The pathology and clinical aspects of intracranial infiltration with leukemic cell:an analysis of 50 auteptlc cases
    白血病细胞颅内浸润的病理与临床——附50例尸检分析
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    Pathology of brain tumors after stereotactic injection of radionuclide of ~(32)p
    立体定向~(32)P内放疗后脑瘤的临床病理研究
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  histopathology
    Studies on the histopathology and ultrastructure of moyamoya disease.
    实验性moyamoya病颈内动脉的组织病理及超微结构研究
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    A Study on Histopathology,Ultrastructure and Monoamine Fluorescent Histochemistry in Experimental Allergic Encephalomyelitis Model
    实验性过敏性脑脊髓炎模型组织病理、超微结构及单胺类介质荧光组化的研究
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    The studies on clinical manifestations,histopathology and imaging of MELAS
    MELAS型线粒体脑肌病的临床、病理及影像学研究
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    EFFECTS OF MK-801 ON CORTICAL HISTOPATHOLOGY AND ULTRASTRUCTURE IN REPEATED CEREBRAL ISCHEMIA IN RATS
    MK-801对反复性脑缺血大脑皮层组织病理和超微结构的影响
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    Establishment of Experimental Autoimmune Encephalomyelitis Model in Guineapigs for the Histopathology and MRI Observations
    实验性自身免疫性脑脊髓炎豚鼠模型的建立及其病理和MRI的观察
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  pathobiology
    parietal frontal region and deep position of crania. Conclusions that 2D sonography and CDFI, powe Doppler can determine the cranial regiou and detect its physcal nature such as the solid, cyst, but can't to mark the pathobiology diagnosis, however that real time measuring the dynamic of blood flow inside or around the tumor is superior to the CT, MRI, and DSA.
    结论为二维超声及彩色多普勒血流显像、能量多普勒能检出脑肿瘤及检测肿瘤的物理性质例如实性、囊性,但不能作出病理诊,但是,实时测量肿瘤内或包绕肿瘤的血流动力学则优于CT、MRI及DSA。
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  neuropathologic
    Objective: To investigate the clinical, neuroelectrophysiologic, neuropathologic and magnetic resonance imaging (MRI) characteristics of patients with subacute combined degeneration (SCD) of the spinal cord, and evaluate the significance of neuroelectrophysiological examinations and MRI in the diagnosis of SCD.
    目的:分析亚急性联合变性的临床、电生理、病理及MRI特点,评价电生理及MRI在诊断本病中的价值。
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    More serious changes were found in nerve tissue following theresupply of oxygen and during the whole stage of global anoxia the level of LPO, Fe and SOD was changed regularly and it showed closed relationship to neuropathologic changes.
    脑缺氧发展金过程LPO、Fe、SOD活性变化有自身内在规律,又与神经病理改变有着内在联系。
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    Methods Brain tissues from 2 cases with PSP and 3 cases with CBD, all confirmed by autopsies, were examined by routine neuropathologic methods, Gallyas-Braak staining and tau immunostaining. Brain tissues from 6 Alzheimer's disease cases, 4 cases with Parkinson's disease and 6 elderly with no neurologic abnormality were used as controls.
    方法 对具有详细临床资料和病理确诊的2例进行性核上性麻痹和3例皮质基底节变性的脑标本进行了Gallyas-Braak银染色和tau蛋白免疫组织化学链霉素抗生物素蛋白-过氧化物酶法染色,并以5例阿尔茨海默病,4例帕金森病和6例无神经疾病史的同龄老年人脑标本作对照。
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      pathology
    It is possible that this mutation severely impairs enzymatic activity and is the underlying basis for the pathology seen in this patient with Hunter syndrome.
          
    The biopsy tissue and the lesion resected in operation were treated with pathology and histological response was counted.
          
    It is totally different from pancreatic carcinoma in epidemiology, histology, pathology and prognosis.
          
    This study investigates the molecular pathology in four families with LQTS (including a family with JLNS) in the Chinese population.
          
    To investigate the biological behavior of GIST, we collected 83 cases of gastric and 62 cases of small intestinal GIST from the Department of Pathology of the Chinese PLA General Hospital.
          
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      histopathology
    Histopathology of the digestive gland of the bivalve mollusk Crenomytilus grayanus (Dunker, 1853) from southwestern Peter the Gr
          
    Identifying the etiologic role of Parvovirus B19 in non-immune hydrops fetalis by histopathology, immunohistochemistry and nucle
          
    Paraffine embedded tissue sections from placental and liver tissues from each case were evaluated by histopathology, immunohistochemistry, nested PCR and commercial quantitative Real-time PCR.
          
    Viral DNA was detected in placental tissues by Real-time PCR in 2 cases (2/22, 9.1%) where histopathology also revealed changes suggestive of Parvovirus B19 infection.
          
    However, histopathology revealed a 2.2×1.5 cm adenocarcinoma.
          
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      pathobiology
    Angiotensin II (Ang II) is central to the pathobiology of atherosclerosis.
          
    Morbid anatomy and pathobiology of arrhythmogenic right ventricular cardiomyopathy
          
    Recent evidence implicates TSLP as playing a pivotal role in the pathobiology of allergic asthma and atopic dermatitis.
          
    Our understanding of the pathobiology of coronary atherosclerosis provides us with new opportunities to reduce myocardial ischemia by interventions that address these mechanisms directly.
          
    Thus, shear stress is critically important in regulating vascular physiology and pathobiology of the vessel wall via the modulation of endothelial cell gene expression.
          
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      neuropathologic
    The neuropathologic evaluation of a case of "sleep epilepsy" revealed a symmetric hyperplasia of the hippocampal formations in the absence of other dysplasias of the central nervous system.
          
    The outstanding neuropathologic findings are axonal swellings which are most numerous in the dorsal regions of the medulla oblongata (especially of the n.
          
    The clinical and neuropathologic features of the "symptomatic occult hydrocephalus with normal cerebrospinal fluid pressure" (Adams-Hakim) occurring in a 59-year-old male are described.
          
    The essential neuropathologic findings in this case of "idiopathic nonobstructive atrophic white matter degeneration with ventricular dilatation" (Messert-Baker) consisted of diffuse periventricular demyelination with isomorphic fibrous gliosis.
          
    Neuropathologic differentiation of progressive supranuclear palsy and corticobasal degeneration
          
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    155 cases of sporadic encephalitis are reported. Among these cases,13 were autopsied. This is a disorder characterized by diverse impairmentsof the central nervous system such as psychiatric disturbance, unconsci-ousness, epilepsy, paralysis, decortical state, etc. In the majority ofthe subjects studies, infectious features were not prominent and therewere no changes in the cerebral spinal fluid. However, in a few cases,slight pleocytosis with a mild increase of protein in the CSF or slightincrease of the intracranial...

    155 cases of sporadic encephalitis are reported. Among these cases,13 were autopsied. This is a disorder characterized by diverse impairmentsof the central nervous system such as psychiatric disturbance, unconsci-ousness, epilepsy, paralysis, decortical state, etc. In the majority ofthe subjects studies, infectious features were not prominent and therewere no changes in the cerebral spinal fluid. However, in a few cases,slight pleocytosis with a mild increase of protein in the CSF or slightincrease of the intracranial pressure was recorded. On the basis of the clinical manifestation, these cases were dividedinto five groups: (1) psychiatric type, (2) intracranial hypertension type,(3) epileptic type, (4) protean clinical manifestation type, and (5) para-lytic type. On pathological examination, two forms were observed. Onewas compatible with virus encephalitis, while another with demyelinateencephalitis. However, pathologically these two forms could be clearlydistinguished, but clinically they were not. It is assumed that sporadic encephalitis may be resulted from morethan one cause. The diagnosis and elucidation of the nature of thedisease need further investigation.

    本文报告散发性脑炎155例,其中13例进行尸解,发现有两类病理改变,一种符合病毒性脑炎;另一种符合急性脱髓鞘性脑炎。两种病例在临床上不易鉴别。因此,对本病的诊断有待从病原学,免疫学及电镜检查等方面进行探索。

    Sturge-Weber syndrome is a congenital disorder with a familial tendency and an irregular dominant heredity. Clinically it is characterized by the presence of cutaneous vascular nevi, convulsive seizures, mental disturbances, buphthalmus, spastic hemiplegia and one-sided hypotrophy of extremites. Roentgenologically intracranial patches or double-contour wavy shadows or multiple flecks are seen in the skull. Pneumoencephalograms reveal atrophy of cerebral hemisphere and dilatation of lateral ventricles of the...

    Sturge-Weber syndrome is a congenital disorder with a familial tendency and an irregular dominant heredity. Clinically it is characterized by the presence of cutaneous vascular nevi, convulsive seizures, mental disturbances, buphthalmus, spastic hemiplegia and one-sided hypotrophy of extremites. Roentgenologically intracranial patches or double-contour wavy shadows or multiple flecks are seen in the skull. Pneumoencephalograms reveal atrophy of cerebral hemisphere and dilatation of lateral ventricles of the corresponding side. Electroencephalographic studies show reduction in amplitude, sharp wave or slow wave focus on the same side as the cutaneous vascular nevi. Pathologically angiomatous changes of face and meninges, calcification in cortical layer and cerebral capillary wall, diminution of ganglion cells and gliosis are evident. The present article is a clinical analysis of 22 cases seen in 1936~1978, Three illustrative cases are appended.

    Sturge-Weber二氏综合征是先天性疾患,似属显性遗传。临床上以皮肤血管痣、搐搦发作、精神症状、眼球突出、痉挛性偏瘫及半身萎缩为特征。颅骨片于枕部示片状或双层波状钙化灶。气脑造影示相应侧大脑半球脑沟增宽及脑室扩大。病理方面皮肤及脑膜有血管痣,脑皮质有钙化灶,神经细胞减少及胶质细胞增生。脑电图常有一侧波幅降低或尖波慢波灶。神经精神症状系脑膜血管瘤压迫所致。本病散见于世界各种族。作者将1936~1978年所见之22例作了临床分析。并附3例病历摘要。

    The brain scans of 118 surgically and pathologically proved cases of intracranial space-occupying lesions were analyzed.The overall percentage of positive diagnosis was 71.2%. The rate of accurate diagnosis was the highest(100%) in meningiomas, metastatic tumors, intracranial hematomas and brain abscesses; while cysts, cholesteatomas, cystic and well-differentiated gliomas often gave false negative results. In comparison with other methods, with the exception of the lesions located in the hemispheres, the rate...

    The brain scans of 118 surgically and pathologically proved cases of intracranial space-occupying lesions were analyzed.The overall percentage of positive diagnosis was 71.2%. The rate of accurate diagnosis was the highest(100%) in meningiomas, metastatic tumors, intracranial hematomas and brain abscesses; while cysts, cholesteatomas, cystic and well-differentiated gliomas often gave false negative results. In comparison with other methods, with the exception of the lesions located in the hemispheres, the rate of positive diagnosis of brain scanning is lower than that of cerebral angiography, pneumoencephalography or ventriculography. Since brain scanning is noninvasive so it is still a method of choice and on the basis of which other methods are selectively used.

    本文分析118例颅内占位性病变的脑扫描,总阳性率 71.2%。按病理性质则脑膜瘤、转移瘤、颅内血肿及脑脓肿的阳性率最高,均为100%;与其它诊断方法相比,本组脑扫描除大脑半球病变外,阳性率低于脑血管、气脑、脑室造影等,但因它为无创伤性,而其它方法多在脑扫描筛选后有选择地进行,故此法仍不失为颅内病变首选的诊断方法。

     
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