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抑制类型
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  inhibition type
     the Ki of GLPAI to PrA was2.7μmol/L and the inhibition type was the complex of non-competitive andanti-competitive inhibition.
     对PrA的Ki=2.7(μmol/L),抑制类型为竞争和非竞争性混合抑制作用。
短句来源
     The inhibition type of Pb(NO_3)_2 on PLAP was determined by using the double reciprocal plot.
     用双倒数作图法确定Pb(NO3)2对该酶的抑制类型
短句来源
     the Ki of GLPAI to trypsin was 33.5μmol/L and the inhibition type was thecomplex of non-competitive and competitive inhibition;
     对胰蛋白酶的Ki=33.5(μmol/L),抑制类型为竞争和非竞争性混合抑制作用;
短句来源
     4. The kinetics studies of GLPAI showed that :the Ki of GLPAI to pepsin was 4.64μmol/Land the inhibition type was the complex of non-competitive and anti-competitiveinhibition;
     4.GLPAI的动力学研究结果表明:GLPAI对胃蛋白酶的Ki=4.64(μmol/L),抑制类型为非竞争和反竞争性混合抑制作用;
短句来源
     It shows that the velocity of the combining of the inhibitor and α-glucosidase is very fast. The inhibition type is competitive,Km =2.343×10-3mol/L.
     其抑制动力学试验表明,抑制成分的抑制类型属竞争性抑制,Km=2.343×10-3mol/L。
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  “抑制类型”译为未确定词的双语例句
     The survey of effects of metal ions on the AKP activity shows that Na+、K+、and Li+ have not any effect on the enzyme activity, Mg2+、Ca2+、Ba2+、Ni2+、Mn2+、Co2+ and Zn2+ could activate the enzyme, and Cu2+、Hg2+、Cd2+ and Ag+ will inhibit the enzyme.
     Na+、K+和Li+等正一价金属离子对酶活力无影响。 Mg2+、Ca2+、Ba2+、Ni2+、Mn2+、 Co2+、Zn2+对酶均为激活作用,Cu2+、Hg2+、Cd2+及Ag+为抑制作用,并且Cu2+对酶的抑制类型为非竞争抑制类型
     CuSO_4,Cd(NO_3)_2 was selected for determing types of inhibition,and the result showed that CuSO_4 was a noncompetitive inhibitor,the inhibition constant being 1.32×10~(-3)mol/L,Cd(NO_3)_2 was a competitive inhibitor,with inhibition constant 3.33×10~(-4)mol/L.
     选用CuSO4、Cd(NO3)2作酶的抑制类型判断,结果表明,CuSO4为非竞争性抑制,抑制常数为1 32×10-3mol/L,Cd(NO3)2为竞争性抑制,抑制常数为3 33×10-4mol/L。
短句来源
     These inhibitions could be divided by Lineweaver-Burk plot into non-competitive and competitive and other types whose inhibition constants were 5.87 mmol/L,2.47 mmol/L and 8.2 mmol/L,respectively.
     利用L inew eaver-Burk作图法判定抑制类型分别为非竞争性、竞争性和非竞争性抑制,抑制常数分别为5.87、2.47和8.2μm o l/L.
短句来源
     The inhibition of Cu2+, Cr3+ and Fe3+was demonstrated to be noncompetitive inhibition by using Lineweaver-Burk method and those Ki values were 3.58×10-3mol/L, 3.25×10-4mol/L and 6.15×10-4mol/L determined by Dixon method.
     利用双倒数作图法研究Cu~(2+)、Cr~(3+)、Fe~(3+)对酶的作用,结果表明这些离子对酶的抑制作用为非竞争性抑制类型,用Dixon作图法求出其抑制常数犬i值分别为3.58xlo一3mol/L,3.25、10一4mol/L和6.15、10一4mol/L。
短句来源
     The inhibition of papain by lily CPI was competitive,with a K_1 value of 1. 1 5 ×10 ̄(-9) mol/L and the mole ratio was 8. 5: 1.
     对木瓜蛋白酶的抑制属竞争性抑制类型,其Ki值为1.15×10~(-9)mol/L,对木瓜蛋白酶的抑制摩尔比为8.5:1.
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  相似匹配句对
     Inhibition
     抑制
短句来源
     Types of Artificial Satellites
     人造卫星的类型
短句来源
     Types of Farewell
     告别类型
短句来源
     inhibit the apoptosis;
     抑制细胞凋亡;
短句来源
     The Noise Sorts and the Suppression Methods on the Upstream Channel in HFC
     HFC上行通路的噪声类型抑制方法
短句来源
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  inhibition type
The ethanol effect on the Trichoderma reesei cellulases was studied to quantify and clarify this inhibition type.
      
The second aim was to study the inhibition type of niflumic acid (NA) for MPA glucuronidation in human liver.
      
The inhibition type of NA for MPA glucuronidation was studied in 5 human liver samples.
      
The inhibition type of NA for MPA glucuronidation was mixed non-competitive.
      
Dynamics of excitation patterns is studied in one-dimensional homogeneous lateral-inhibition type neural fields.
      
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A series of 9 compounds of the bis-tolyloxyalkane-bis-quaternary salts were synthesized by Kyi and Huang. Their actions on the nerve-muscle preparation of them. tibialis anticus and the superior cervical ganglion of the cat were investigated. All these compounds possessed neuromusular blocking action, among them AMBA-1 (1, 1-bis-p-tolyloxy-methane bis-trimethyl ammonium dibromide) was the most active with a potency twice that of d-tubocurarine. The mechanisms of their neuromuscular blocking actions were different....

A series of 9 compounds of the bis-tolyloxyalkane-bis-quaternary salts were synthesized by Kyi and Huang. Their actions on the nerve-muscle preparation of them. tibialis anticus and the superior cervical ganglion of the cat were investigated. All these compounds possessed neuromusular blocking action, among them AMBA-1 (1, 1-bis-p-tolyloxy-methane bis-trimethyl ammonium dibromide) was the most active with a potency twice that of d-tubocurarine. The mechanisms of their neuromuscular blocking actions were different. Compounds with trimethyl ammonium methyl groups at para- and meta-positions resembled decamethonium in antagonim to curare, lack of antagonism by prostigmine and persistence of tetanie contraction in spite of the reduction of twitch height; and those with trimethyl ammonium methyl groups at ortho-position resembled d-tubocurarine in potentiation of d-tubocurarine paralysis, antagonism by prostigmine, and rapid decay of tetanic contraction. AMBA-1, 2, 3, 4, 5, possessed feeble ganglion-blocking action at doses higher than those for blocking neuromuscular transmission, but AMBA-11, 21, 22, 23, were not active. Anticholinesterase actions of these compounds were tested manometrically and compared with physostigmine and prostigmine at the equimolar concentration (3×10~(-6) M). AMBA-4 was the most active (40% inhibition), but weaker than physostigmine and prostigmine.

(一)9个双甲苯氧烷季銨盐都具有神經肌肉阻断作用,其中AMBA-1作用最强,約为d-筒箭毒鹼的两倍。在作用机制上,三甲氨甲基附着于苯环对位或間位的化合物AMBA-1,2,3,4,5,11屬于去極化类型,而三甲氨甲基附着于苯环的邻位的化合物AMBA-21,22,23則屬于竞爭性抑制类型。 (二)这几个化合物对神經节的作用很弱。 (三)在抗胆鹼酯酶作用上,这些化合物都有一定的作用,其中以AMBA-4最强,在3×10~(-6)M濃度时抑制酶活力40%。 (四)这9个化合物主要作用点在横紋肌上,其中以AMBA-22比較符合理想的横紋肌松弛藥的要求,因此正在进一步地研究以确定其是否有实际应用的价值。

An alkaline phosphatase was partly purified from amphioxus by extraction, ammonium sulfate fractionation,pH regulation and get filtration with Sephadex G-100.Preliminary kinetic studies of the enzyme were undertaken. The results are as follows:The optimum pH of alkaline phosphatase for the hydrolysis of disodium phenyl phosphate is 10.1,and the optimum temperature is 40℃ .The Michaelis -Menten constant Km is1.13×10-3M at pH 10.1.Under given experimental conditions,the Michaelis-Menten constant Km varies with...

An alkaline phosphatase was partly purified from amphioxus by extraction, ammonium sulfate fractionation,pH regulation and get filtration with Sephadex G-100.Preliminary kinetic studies of the enzyme were undertaken. The results are as follows:The optimum pH of alkaline phosphatase for the hydrolysis of disodium phenyl phosphate is 10.1,and the optimum temperature is 40℃ .The Michaelis -Menten constant Km is1.13×10-3M at pH 10.1.Under given experimental conditions,the Michaelis-Menten constant Km varies with different pH values whereas the maximal velocity Vmax remains unchanged which indicates thatthe effect caused by pH is of the competitive type.The alkaline phosphate is strongly activated by Mg++ ion hut is inhibited by Zn++, EDTA,DFP,2-mercaptoethanol and PCMB. The Ki's of three inhibitors were determined and were found to be of the noncompetitive type. The marked inhibition of 2-mercaptoethanol on the enzyme suggests that the disulfide bond is easential to the maintainance of the enzyme activity. From the v versus pH plot,the pK value of the dissociation of the active group is 9.82 which suggests that -NH2 group might be an active group of the enzyme.The energy of activation is 3.16 kcal/mole, the temperature coefficient Q10(at 30-40℃)is 1.15.

从厦门文昌鱼中部份提纯一种碱性磷酸酶,并对该酶作用的动力学进行了初步的研究。该酶作用于底物磷酸苯二钠的最适pH为10.1,最适温度为40℃,测得其米氏常数值(K_m)为1.1×10~(-3)M,pH影响K_m值而不影响最大反应速度(V),表现为竞争性类型。Mg~(++)有明显的激活作用,而Zn~(++),EDTA,DFP,ME及PCMB等在一定浓度范围内,表现为非竞争抑制类型。ME的抑制作用表明硫硫键是维持酶活力所必需的。从pH对酶的活力影响,测得有关酶活性基团解离的pK值为9.82,在不同温度条件下,测得该酶的活化能为3.16仟卡/克分子,其温度系数为1.15(30—40℃)。

5, 5'-Dithio-bis-(2-nitrobenzoio acid) and related compounds are allo-sterio effectors of the acety]cholinesterase from fish (Nebia albiflora) muscle.

5,5'-联硫-2,2'-双硝基苯甲酸(DTNB)及其有关化合物TNB、TNB-Tch都是黄姑鱼肌肉乙酰胆碱酯酶的别构效应剂: 1.TNB非竞争性地抑制、而DTNB则激活该酶水解乙酰硫代胆碱和丁酰硫代胆碱的活力。对水解乙酰胆碱及α-萘酚乙酯的活力皆无影响。2.TNB-Tch比TNB具有更强的抑制作用。且对该酶水解乙酰胆碱、乙酰硫代胆碱及α-萘酚乙酯的活力皆有抑制作用。抑制类型与作用底物有关。底物在外周的结合能解除其抑制。3.钙离子可以解除TNB和TNB-Tch的抑制作用,而箭毒亦能与之对抗。对蛇毒乙酰胆碱酯酶,除了极低浓度(<10μM)DTNB和TNB有微弱的抑制作用外,TNB-Tch以及较高浓度的DTNB和TNB都具有强烈的激活作用。而对猪脑尾核乙酰胆碱酯酶的活力皆无影响。

 
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