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急性创面
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  acute wound
     The Improvement of Microcirculation in Rabbit Acute Wound by V.A.C and Its Relation with NO, ET-1 and NOS
     V.A.C改善兔急性创面微循环与NO,ET-1和NOS的关系
短句来源
     Results:After dealing with the wound which sealing time of acute wound was 1~3 weeks,average time was 2 weeks.
     结果 :经该方法处理创面后创面愈合时间 ,急性创面 1~ 3周 ,平均 2周 ;
短句来源
     Methods Collecting exudate of eight acute wound (breast cancer) at day 1, 2, 3, 4 postoperatively and 11 chronic wound (5 cases of pressure sore, 6 cases venous ulcer) pretreatment and posttreatment of vacuum assisted closure at day 1, 3, 5, 7, 9, we determined Hyaluronic acid content and made comparisons between them based on RIA.
     方法取8例乳癌术后第1、2、3、4天急性创面的引流液,同时收集11例慢性创面(5例压力性溃疡,6例静脉性溃疡)于封闭负压引流治疗前以及治疗后第1、3、5、7、9天的渗出液,利用放射免疫测定的方法分别测定其中透明质酸的含量,并进行动态的观察与比较。
短句来源
     Objective To construct a bio-engineered dermis containing microencapsulated nerve growth factor(NGF)-expressing(NIH3T3) cells and to study the effect of the microencapsule on the bio-engineered dermis and acute wound healing.
     目的探讨微囊化神经生长因子(nerve grow th factor,NGF)基因修饰的N IH 3T 3细胞复合组织工程真皮的可行性及其对急性创面愈合的影响。
短句来源
     METHODS: Twenty-one patients with acute or chronic wound, who were treated at the Tangdu Hospital, Fourth Military Medical University from April 2001 to April 2002 as experimental objects, in which the acute wound patients were breast cancer patients from common surgery with 10 cases, and the chronic wound patients were patients from Department of Plastics and Burns with 11 cases.
     方法:选取2001-04/2002-04第四军医大学附属唐都医院收治的急、慢性创面患者21例为实验对象,其中急性创面患者为普通外科乳腺癌手术患者,共10例,慢性创面患者为烧伤整形科收治的患者,共11例。
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  “急性创面”译为未确定词的双语例句
     The periods of wound healing were 25±2 days in group A,34±3 days in group B,34±2 days in group C,33±2 days in group D and 40±3 days in group E. The period of wound healing was decreased about 10 days at least.
     移植治疗急性创面,A组平均愈合时间为25±2 d,B组为34±3 d,C组为34±2 d,D组为33±2 d,E组为40±3 d,A组创面愈合时间平均至少缩短约10 d,提高了创面愈合的速度。
短句来源
     Results The expression of uPA and uPAR protein in margin tissues of pigs with acute wounds increased and peaked in 3 days after the treatment with V.A.
     结果猪急性创面在封闭负压引流治疗后uPA和uPAR均增加,在第3天达到高峰,然后急速下降,但实验组的基因表达量和染色强度均显著高于对照组。
短句来源
     Methods The exudates of acute wounds (postoperative breast cancer) were postoperatively collected at day 1,2,3,and in 6 chronic wounds (4 cases of venous ulcer, 2 cases of pressure sore) the exudates were also collected before and 2,4,6 days after the treatment with VAC. The type-III collagen degradation from the exudates was checked with zymography timepoint. The types of the collagenase in exudates were evaluated by using doxycycline inhibition.
     方法取4例急性创面在术后1、2、3d的创面引流液(乳癌术后),同时收集6例慢性创面(4例静脉性溃疡,2例压力性溃疡)在VAC治疗前以及治疗后2、4、6d的创面渗出液,利用酶谱分析的方法,观察各时间点的渗出液对可溶性III型胶原的降解情况,同时应用强力霉素抑制实验来分析渗出液中胶原酶的类型。
短句来源
     Aim: To observe the effects of recombinant bovine basic fibroblast growth factor (rbFGF) on acute and chronic wounds healing.
     目的 :观察基因重组牛碱性成纤维细胞生长因子 (rbFGF)对急性创面和慢性创面愈合的促进作用。
短句来源
     C on the expression of c-myc , c-jun and Bcl-2 protein in margin tissues of pigs with acute wounds and patients with chronic wounds. Result: We found that in general, the expression of c-jun , c-myc and Bcl-2 protein in margin tissues of pigs with acute wounds increased and peaked at day 1, 3, 9 respectively after treatment with V.A.
     1.V.A.C对猪急性皮肤缺损创面和人慢性皮肤创面原癌基因c-jun、第四军医大学硕士学位论文c一myc和Bd一2表达的影响。 结果:猪急性创面在VA.
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  相似匹配句对
     Result: We found that in general, the expression of uPA, uPAR protein in margin tissues of pigs with acute wounds increased and both peaked at day 3 after treatment with V.A.
     结果:猪急性创面在V.A.
短句来源
     Acute Infectious Hepatitis (4)
     急性传染性肝炎
短句来源
     Acute Posterior Ischemic Optic Neuropathy
     急性后部缺血性视神经病变
短句来源
     Changes in inflammatory response in acute radiation-induced skin wounds in rats and its mechanism
     急性放射性皮肤烧伤创面炎症反应的变化及其机制探讨
短句来源
     the wound's ober- vation and nursing;
     创面的观察及护理;
短句来源
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  acute wound
The decreased functional activity of the endocrine and immune systems suggests that AO considerably decelerates the systemic body response (general adaptation syndrome) to acute wound.
      
A variety of local, regional, and even free microvascular flaps are available for acute wound closure in such cases.
      
Histological evidence suggests that pressure relief results in chronic foot ulcers changing their morphological appearance by displaying some features of an acute wound.
      
Forty-nine (6.96%) of the 704 compound fractures became infected (acute wound infection and/or chronic osteomyelitis).
      
Exclusion criteria were arterial occlusive disease, diabetes mellitus, acute wound infection, thrombocytopenia and pregnancy.
      
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Objective:To observe the effect of vacuum-sealing technique on the wound healing.Methods:The patients with the wound that were differ in depth and in size,which were treated with multiply hole sponge vacuum sealing technique.Results:After dealing with the wound which sealing time of acute wound was 1~3 weeks,average time was 2 weeks.Sealing time of chronic wound was 2~8 weeks,average time was 4 weeks.Conclusion:This technique compare with the traditional method are of simple,sealing property is good,the wound...

Objective:To observe the effect of vacuum-sealing technique on the wound healing.Methods:The patients with the wound that were differ in depth and in size,which were treated with multiply hole sponge vacuum sealing technique.Results:After dealing with the wound which sealing time of acute wound was 1~3 weeks,average time was 2 weeks.Sealing time of chronic wound was 2~8 weeks,average time was 4 weeks.Conclusion:This technique compare with the traditional method are of simple,sealing property is good,the wound healing speech is rapid and cross infection opportunity is rare.

目的 :观察负压封闭治疗创面的效果。方法 :采用多孔敷料负压封闭疗法 ,对不同深度及大小的急、慢性创面进行处理。结果 :经该方法处理创面后创面愈合时间 ,急性创面 1~ 3周 ,平均 2周 ;慢性创面 2~ 8周 ,平均 4周。结论 :多孔敷料负压封闭处理创面与传统方法相比较 ,具有操作简单、密闭好、创面愈合速度加快、降低交叉感染等优点

Aim: To observe the effects of recombinant bovine basic fibroblast growth factor (rbFGF) on acute and chronic wounds healing. Methods: 1 282 cases with acute wounds such as burn, donor site or operative wounds and chronic wounds were treated with bFGF. Another 439 cases with the similar wounds were used as control. The complete healing time, healing rates and adverse reaction of wounds healing were observed. Results: In superficial Ⅱ degree burn wounds, the healing rate for 8 days post-burn and complete healing...

Aim: To observe the effects of recombinant bovine basic fibroblast growth factor (rbFGF) on acute and chronic wounds healing. Methods: 1 282 cases with acute wounds such as burn, donor site or operative wounds and chronic wounds were treated with bFGF. Another 439 cases with the similar wounds were used as control. The complete healing time, healing rates and adverse reaction of wounds healing were observed. Results: In superficial Ⅱ degree burn wounds, the healing rate for 8 days post-burn and complete healing time was 51.7%±26.4% and (12.6±2.9)d (P<0.001) respectively in control group and was 70.6%±25.0% and (10.5±2.4)d (P<0.001) respectively in trial group. In deep Ⅱ degree burn wounds, the healing rate for 15 days post-burn and complete healing time was 53.3%±25.4% and (21.9±5.5)d (P<0.001) respectively in control group and was 69.7%±27.0% and (18.5±4.4)d (P<0.001) respectively in trial group. In operative wounds, the healing rate for 8 days and complete healing time was 57.6%±29.4% and (11.4±2.7)d (P<0.001) respectively in control group, and was 72.1%±28.0% and (9.5±2.4)d (P<0.001) respectively in trial group. In chronic wounds, the complete healing time was (28.0±18)d in control group and (22.1±16.0)d in trial group (P=0.068). Conclusion: Recombinant bovine basic fibroblast growth factor (rbFGF) can improve the quality and the velocity of wound healing significantly.

目的 :观察基因重组牛碱性成纤维细胞生长因子 (rbFGF)对急性创面和慢性创面愈合的促进作用。方法 :治疗组 (12 82例 )和对照组 (439例 )被分为深Ⅱ度烧伤、浅Ⅱ度烧伤、供皮区 (包括刃厚和中厚供皮区 )和慢性 (包括残余小创面和慢性溃疡 )创面 4大类。分别观察应用rbFGF后不同时间创面愈合面积的百分比、创面完全愈合时间 ,以及用药前后的全身情况和不良反应。结果 :浅Ⅱ度烧伤 8d愈合率和创面完全愈合时间 ,对照组为 5 1 7%± 2 6 4 %和 (12 6± 2 9)d(P <0 0 0 1) ,治疗组为 70 6 %± 2 5 0 %和 (10 5± 2 4 )d(P <0 0 0 1)。深Ⅱ度烧伤 15d愈合率和创面完全愈合时间 ,对照组为 5 3 3%± 2 5 4 %和 (2 1 9± 5 5 )d(P <0 0 0 1) ,治疗组为 6 9 7%± 2 7 0 %和 (18 5± 4 4 )d(P <0 0 0 1)。供皮区创面 8d愈合率和创面完全愈合时间 ,对照组为 5 7 6 %± 2 9...

目的 :观察基因重组牛碱性成纤维细胞生长因子 (rbFGF)对急性创面和慢性创面愈合的促进作用。方法 :治疗组 (12 82例 )和对照组 (439例 )被分为深Ⅱ度烧伤、浅Ⅱ度烧伤、供皮区 (包括刃厚和中厚供皮区 )和慢性 (包括残余小创面和慢性溃疡 )创面 4大类。分别观察应用rbFGF后不同时间创面愈合面积的百分比、创面完全愈合时间 ,以及用药前后的全身情况和不良反应。结果 :浅Ⅱ度烧伤 8d愈合率和创面完全愈合时间 ,对照组为 5 1 7%± 2 6 4 %和 (12 6± 2 9)d(P <0 0 0 1) ,治疗组为 70 6 %± 2 5 0 %和 (10 5± 2 4 )d(P <0 0 0 1)。深Ⅱ度烧伤 15d愈合率和创面完全愈合时间 ,对照组为 5 3 3%± 2 5 4 %和 (2 1 9± 5 5 )d(P <0 0 0 1) ,治疗组为 6 9 7%± 2 7 0 %和 (18 5± 4 4 )d(P <0 0 0 1)。供皮区创面 8d愈合率和创面完全愈合时间 ,对照组为 5 7 6 %± 2 9 4 %和(11 4± 2 7)d(P <0 0 0 1) ,治疗组为 72 1%± 2 8 0 %和 (9 5± 2 4 )d(P <0 0 0 1)。慢性创面完全愈合时间 ,对照组为 (2 8 0± 18 0 )d ,治疗组 (2 2 1± 16 )d(P =0 0 6 8)。用药前后血常规、肝、肾功能无异常变化。结论 :基因重组牛碱性成纤维细胞生长因子能够显著地促进创面

Objective To study the effect of the vacuum-assisted closure(VAC)on activated gelatinases(MMP-2,62KD;MMP-9,82KD)in human chronic wound.Method Five patients who underwent chronic wounds are treated with VAC applying a negtive pressure(-120mmHg ).Wound Fluids are obtained before th e treatment and 24hours,3days,5days,10days and 15days after the treatm ent.The fluids of10patients who underwent mastectom ies are used as controlled group.Wou nd fluid samples are analyzed with zy mography and Densitome-try.Result...

Objective To study the effect of the vacuum-assisted closure(VAC)on activated gelatinases(MMP-2,62KD;MMP-9,82KD)in human chronic wound.Method Five patients who underwent chronic wounds are treated with VAC applying a negtive pressure(-120mmHg ).Wound Fluids are obtained before th e treatment and 24hours,3days,5days,10days and 15days after the treatm ent.The fluids of10patients who underwent mastectom ies are used as controlled group.Wou nd fluid samples are analyzed with zy mography and Densitome-try.Result Before the VAC treatment,two sample s contain higher activated MMP-2or a ctivated MMP-9,and the total activity of activited glatinases than controlled group.After 15-day treatment there are no significant statistic difference in a ctivated glatinases and the total activity of activited glatinases between chr onic wounds and acute wounds(P>0.05).Conclusion Activated gelatinases may be one of t he causes retarding the process of human chron ic wound healing when they are too hig h or too low.The VAC can modulate acti vity of activated gelati-nases in human chronic wound.

摘要:目的研究封闭负压引流技术对人慢性创面中活性形式明胶酶(活性MMP-2、活性MMP-9)的影响。方法对5例慢性创面患者给予创面封闭负压引流(-120mmHg压力)150d,分别于吸引前和吸引后24h、3、5、10、15d收集创面渗出液。另以10例乳腺癌切除术后第3天的创面引流液为急性创面对照。用Zymography法测明胶酶活性,并用薄层分析仪分析试验结果。结果封闭负压引流治疗前,1例的活性MMP-2和另1例的活性MMP-9较对照组高,两例的活性形式明胶酶总活性(两种酶活性之和)较对照组活性高。封闭负压引流治疗后,慢性创面渗出液中活性MMP-2、活性MMP-9及活性形式明胶酶总活性与对照组比较无统计学差异(P>0.05)。结论人慢性创面中活性形式明胶酶的活性过低或活性过高均可能是慢性创面长期不愈的原因,封闭负压引流能调节慢性创面中活性形式明胶酶的活性。

 
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