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   心肌活性 的翻译结果: 查询用时:0.444秒
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心血管系统疾病
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心肌活性
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  myocardial viability
     [Methods] 78 AMI patients were performed 99mTc-HL91 hypoxia imaging to detect the myocardial viability,calculated 99mTc-HL91 uptake rate of infarction myocardium.
     方法78例AMI患者在治疗前行99mTc-HL91乏氧显像检测心肌活性,并计算梗死心肌的99mTc-HL91摄取率。
短句来源
     An experimental study of ~(99)Tc~m-HL91 in detection of myocardial viability
     ~(99)Tc~m-HL91在心肌活性检测中的应用
短句来源
     Result: Xinguantong 1 Herbal Compound lessened clinical symptoms, bettered ischemic myocardium, decreased cardiomyocyte apoptosis, improved cardiac function and myocardial viability of pcitients with AMI significantly greater (P<0.01 or P<0. 05) than the improvement made in its controls.
     结果:心冠通Ⅰ号能够明显改善患者的临床症征,改善心肌缺血,抑制心肌细胞凋亡,提高心肌活性和改善心功能,疗效明显优于对照组(P<0.01或P<0.05)。
短句来源
     Conclusion 31 P-MRS can discribe metabolic characterization of myocardium, and thus has clinical utility for assessing myocardial viability.
     结论 3 1P MRS可以显示心肌梗死后心肌能量代谢的变化 ,从而评价局部心肌活性
短句来源
     Conclusion After acute myocardial ischemia and reperfusion, different quantitative pathologic changes occur in normal, ischemic and infracted regions. A combination of Gd DTPA enhanced dynamic MRI, cine MRI and dobutamine stress test can significantly improve the accuracy and sensitivity in detecting acute myocardial ischemia and reperfusion injury, and is valuable in forecasting the myocardial viability.
     结论 急性缺血再灌注损伤后 ,不同的损伤区具有不同的定量病理学特征 ,Gd DTPA动态增强、cine MRI及多巴酚丁胺负荷试验可以提高对心肌急性缺血再灌注损伤检出的敏感性和准确性 ,预测心肌活性
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  “心肌活性”译为未确定词的双语例句
     Necrosis segments determined by PET significantly higher than contrast-enhanced MR imaging (χ~2= 5,P=0.0253,Kappa=0.8028) and cine MRI (χ~2=7,P=0.0082, Kappa=0.7079), it was also higher than TTC(χ~2=3,P=0.0833, Kappa=0.8879), but had no significant statistic difference.
     PET检出的坏死节段多于MR心肌活性扫描(χ2=5,P=0.0253,Kappa=0.8028)和电影扫描(χ2=7,P=0.0082,Kappa=0.7079),并有统计学意义; 亦多于TTC染色显示的坏死节段,但无统计学意义(χ2=3,P=0.0833,Kappa=0.8879);
短句来源
     Necrosis segments determined by contrast-enhanced MRI had no significant statistic difference with TTC(χ~2=2,P=0.1573, Kappa=0.9130).
     MR心肌活性扫描检出的坏死节段和TTC染色显示的坏死节段相比无统计学意义(χ2=2,P=0.1573,Kappa=0.9130)。
短句来源
     Perfusion was abnormal in 34(30.36%) segments. Delayed hyperenhancement was observed in 12(10.71%) segments.
     心肌灌注扫描见34个(30.36%)节段缺血,心肌活性扫描见12个(10.71%)节段坏死;
短句来源
     Using TTC as the gold standard, the sensitivity and specificity of cine MRI, contrast-enhanced MRI, PET and SPECT in the determination of unviable myocardium were 71.43%,100.00%;
     以TTC染色结果为金标准,MR电影、MR心肌活性扫描、PET和SPECT检出无活性心肌的敏感性、特异性分别为71.43%、100.00%;
短句来源
     The Hypoxia-avid Imaging Agent ~(99)Tc~m-HL91 in Distinguish Myocardial Infarction from Myocardial Ischemia
     乏氧显像剂~(99)Tc~m—HL91在心肌活性检测中的应用
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  相似匹配句对
     Elevations of the levels of the myocardial TNFα and the MPO activity were found.
     心肌组织MPO活性升高。
短句来源
     The myocardium LPO decreased, SOD increased.
     降低心肌 L P O 含量,增加 S O D 活性
短句来源
     Activated Carbon Fibers
     活性碳纤维
短句来源
     Active Packaging Materials
     活性包装材料
短句来源
     MYOCARDIAL PROTECTION
     心肌保护
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  myocardial viability
Quantitative PET imaging at rest allows for detection of myocardial viability since cellular survival is based on maintenance of a minimal perfusion and structural changes correlate to the degree of perfusion reduction.
      
The flow of the necrotic tissue was below 13 ml/100 g min without exception, indicating a threshold perfusion for maintenance of myocardial viability.
      
The objective of this study was to determine the impact of ischemic glycolysis on membrane integrity and myocardial viability during total ischemia.
      
We further discuss the role of delayed contrast-enhanced MRI and low-dose dobutamine cine MRI for evaluation of myocardial viability.
      
Single photon emission computed tomography perfusion imaging for assessment of myocardial viability and management of heart fail
      
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The purpose of this study was to use a direct method-electron spin reso-nance (ESR) spectroscopy to demonstrate the early post-ischemic reperfusion induced enhance of oxygen free radicals. The results showed that the isolated perfused rat heart subjected to 30-minute ischemia followed by 15-second reperfusion revealed a significant increase of oxygen free radicals production in myocardium, compared with 30-minute ischemia group and 30-minutes nor-mal aerobic group. It is featured by a higher ratio of signal...

The purpose of this study was to use a direct method-electron spin reso-nance (ESR) spectroscopy to demonstrate the early post-ischemic reperfusion induced enhance of oxygen free radicals. The results showed that the isolated perfused rat heart subjected to 30-minute ischemia followed by 15-second reperfusion revealed a significant increase of oxygen free radicals production in myocardium, compared with 30-minute ischemia group and 30-minutes nor-mal aerobic group. It is featured by a higher ratio of signal 0 (g = 2.026) and signal S (g = 2.004) of ESR spectra (O/S ratio) in reperfusion group (0.47±0.03) than that in ischemia group (0.29 ± 0.04, P<0.01) and normal group(0.34±0.04> P<0.05), respectcAelg SOD(140μ/ml) added to the perfusate 10 minutes prior to ischemia and during reper-fusion significantly decreased the O/S ratio to 0.35±0.04(P<0.05). Combined use of SOD and diltiazem (2.5 × 10-6M) significantly reduced the O/S ratio to 0.26±0.006 (P<0.01). The post-ischemic reperfusion also induced decrease of myocardial contraction and increase of resting tension and creatine kinase release. Diltiazem sig-nifecantly inhibited the rise of resting tension and creatine kinase release.These results indicate that more oxygen free radicals are produced in the early period of reperfusion. The mechanisms of generation of oxygen free radicals are discussed.

据报道,心肌缺血——再灌损伤的机制与活性氧自由基的产生紧切相关,在大鼠心脏产生氧自由基是以黄嘌呤氧化酶(XO)途径为主.心肌中的黄嘌呤脱氢酶(XD)在Ca~(2+)激活水解酶的作用下向XD转化.而此我们设想,协同使用钙拮抗剂与超氧阴离子(O_2~1)清除剂(超氧化物歧化酶,SOD)可能加强对心肌的保护作用.本实验用电子自旋共振波谱仪(ESR)直接检测大鼠缺血——再灌心肌产生的活性氧自由基,从心脏收缩幅度,静息张力,肌酸激酶(CK)释放和心肌组织丙二醛(MDA)为指标,观察钙拮抗剂硫氮(艹卓)酮(DTZ)和SOD的分别作用和联合作用,发现两药合用可明显减少心肌活性氧自由基的产生.

PURPOSE To test the preliminary clinical performance of 4 rings/7 slices, AFOV 8 cm PET scanner made in China. METHODS Based on phantom test and animal study, PET imaging were performed on a normal volunteer and 7 patients 1 5 hours after intravenous injection of 370MBq of 18 F FDG. The acquisition time of whole body imaging for adult was 1 5 hours (11 bed position), whereas myocardium and brain imaging was 0 5 hours (2~3 bed position). RESULTS Φ 1~3 cm positive and negative foci could be displayed...

PURPOSE To test the preliminary clinical performance of 4 rings/7 slices, AFOV 8 cm PET scanner made in China. METHODS Based on phantom test and animal study, PET imaging were performed on a normal volunteer and 7 patients 1 5 hours after intravenous injection of 370MBq of 18 F FDG. The acquisition time of whole body imaging for adult was 1 5 hours (11 bed position), whereas myocardium and brain imaging was 0 5 hours (2~3 bed position). RESULTS Φ 1~3 cm positive and negative foci could be displayed in phantom. 8 cases of coronal and sagital whole body tomographic images were clearly demonstrated. Brain, myocardium and bladder were significantly displayed in normal volunteer with normal food and drink. 6 malignant lesions of 2 patients concentrated 18 F FDG significantly and 2 benign lesions of 2 patients did not concentrated it. Recurrence and metastasis were excluded in 2 patients with carcinoma after operation and chemotherapy. Whether normal myocardium display or not were dependent on glucose loading. 18 F FDG myocardium images matched well with 99m Tc MIBI myocardial perfusion images in a patient with remote myocardial infarction. Cerebral cortex images well visualized in all subjects. CONCLUSIONS [WT5”BZ]The performance of this PET scanner showed that it reached the level of middle stage of 8th decade's 4 rings/7 slices PET and possessed the coronal and sagital whole body tomographic function of 9th decade's PET. It can be used in whole body tumor imaging, myocardial viability evaluation and preoperation localization of functional epileptic foci, but operating and software function should be improved.

对我国1996年研制成功的4环/7层PET仪(轴向视野8cm)进行试用。先进行模型试验和动物实验,然后对1例正常志愿者和7例患者进行18F脱氧葡萄糖(FDG)PET显像。静脉注射18FFDG370MBq后约15小时显像,成人全身显像行11个床位采集,约15小时,心脑局部显像行2~3个床位采集,约半小时。直径1~3cm的阴模和阳模皆可显示。8例全身冠状和矢状断层影像清晰,正常志愿者(正常进食)可见脑和心肌显影,膀胱内放射性较多。2例恶性肿瘤患者的6处病变浓聚18FFDG。2例恶性肿瘤患者手术和化疗后无复发征,显像阴性。2例良性病变处未见18FFDG浓集。1例陈旧性心肌梗塞患者18FFDG心肌断层显像与99mTc甲氧基异丁基异腈心肌血流灌注显像匹配良好。正常心肌显影与否受葡萄糖负荷的影响。8例脑皮质横断影像良好,基底节和丘脑影像有时尚欠清晰。初试结果表明,该PET仪相当于至今尚在国外广泛使用的80年代中期4环/7层PET仪水平,但具有90年代PET仪全身整体冠状和矢状断层显像的功能,可用于全身肿瘤显像、心肌活性判断和功能性癫痫灶术前定位,但仪器操作性能和软件功能尚需进一步完善。

The method of Doppler tissue imaging(DTI)was performed in 20 patients with coronary artery disease with purpose to detect the velocity of left ventricular wall motion under low dose dobutamine test.The ischemic myocardial viability was assessed.It showed that the velocity of the asynergic segment was significantly lower than normal subject(P<0 05).Among the 100 asynergic segments,35 segments improved after dobutamine infusion in Group A,no significant changes were observed in Group B.The values of Vs and VR...

The method of Doppler tissue imaging(DTI)was performed in 20 patients with coronary artery disease with purpose to detect the velocity of left ventricular wall motion under low dose dobutamine test.The ischemic myocardial viability was assessed.It showed that the velocity of the asynergic segment was significantly lower than normal subject(P<0 05).Among the 100 asynergic segments,35 segments improved after dobutamine infusion in Group A,no significant changes were observed in Group B.The values of Vs and VR in Group A were significantly higher than that of Group B.This study indicated that DTI is of value for assessment of myocardial ischemia and the viable ischmic myocarium.

本文报道了应用多普勒组织成像(DTI)检测冠心病室壁运动异常,并配合小剂量多巴酚丁胺负荷超声心动图判断心肌活性。结果显示:冠心病室壁运动异常节段的收缩期,舒张期速度均低于正常组(P<0.05)。应用小剂量多巴酚丁胺后,100个异常节段中,35个节段运动改善(心肌存活组,A组),65个节段无明显变化(坏死心肌组,B组);DTI检测A组的收缩期速度Vs与速度增长率VR均明显高于B组。表明DTI对心肌缺血及缺血心肌活性的判断有一定价值

 
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