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阴茎勃起功能障碍
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  erectile dysfunction
     Results The incidence rates of erectile dysfunction (ED) at 1 month, 3 months and 1 year after PKRP or TURP were 3.2%, 2.1%, 2.1% and 13.7%, 10.5%, 9.5% respectively.
     结果PKRP、TURP术后1个月、3个月及1年阴茎勃起功能障碍(ED)发生率分别是3.2%、2.1%、2.1%和13.7%、10.5%、9.5%。
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     Objective To evaluate the application value of the nocturnal penile tumescence test ( NPT) in the etiological diagnosis of erectile dysfunction after trauma.
     目的探讨夜间阴茎勃起试验(nocturnal penile tumescence,NPT)在外伤后阴茎勃起功能障碍(erectile dysfunction,ED)病因诊断中的价值。
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     A clinical analysis of 140 cases of erectile dysfunction
     阴茎勃起功能障碍140例临床分析
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     Clinical analysis of 38 cases of erectile dysfunction due to venereal disease
     性病致阴茎勃起功能障碍38例临床分析
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     Results postoperative complications included residual or recurrent adenoma in 11 cases(5.6%),urethral stricture in 22 cases(10.3%),postoperative bleeding in 16 cases(7.4%),postoperative incontineuce in 11 cases(5.1%),and erectile dysfunction in 8 cases(3.7%). All these complications were cured with operation and non-operation methods.
     结果手术后并发症:腺体残留或复发12例(5.6%)、尿道狭窄22例(10.3%)、继发性出血16例(7.4%)、术后尿失禁11例(5.1%)、阴茎勃起功能障碍8例(3.7%),均经手术及保守治疗好转或治愈。
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  penile erectile dysfunction
     Conclusion The dissociated CCMC can serve as a material for thestudy of electrophysilogical mechanism of penile erectile dysfunction by patch clamp.
     结论酶解消化快速分离兔阴茎海绵体平滑肌细胞为全细胞膜片钳技术研究阴茎勃起功能障碍的电生理机制提供了较好的实验材料。
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     Diagnostic approaches of penile erectile dysfunction
     阴茎勃起功能障碍诊断方法探讨
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     The results provide experiment basis for selecting and appling α-adrenoceptor antagonists in the treatment of penile erectile dysfunction. 
     本实验结果为临床选用α-AR拮抗剂治疗阴茎勃起功能障碍提供了实验依据。
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     It is reported that plenty of men,especially the aged,have been bothering in penile erectile dysfunction(ED).
     阴茎勃起功能障碍 (ED)是一种影响男性健康的常见疾病。
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     Therapeutic Choices of Penile Erectile Dysfunction
     阴茎勃起功能障碍治疗方法探讨
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  “阴茎勃起功能障碍”译为未确定词的双语例句
     Results The 73 patients occurred early postoperative complications,including residual in 7 cases(9.6%),urethral infection in 12 cases(16.4%),urethra stricture in 18 cases(24.7%),postoperative bleeding in 23 cases(31.5%),light postoperative incontinence in 5 cases(6.8%),erective dysfunction in 6 cases(8.2%) and TURS in 2 cases(2.7%).
     结果手术后早期并发症共73例,腺体残留7例(9.6%),尿路感染12例(16.4%),尿道狭窄18例(24.7%),术后出血23例(31.5%),轻度尿失禁5例(6.8%),阴茎勃起功能障碍6例(8.2%),电切综合征(TURS)2例(2.7%)。
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     Results The prevalence of ED was 84 % before kidney transplantation and it decreased to 54 % in patients with normal renal function after transplantation ( P < 0.05 ).
     结果 肾移植前阴茎勃起功能障碍(ED)发病率为84 %,肾移植后肾功能正常时降至54 %(P<0.05);
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     Significance and clinical analysis of NPT in 80 ED patients
     夜间阴茎勃起试验检测80例阴茎勃起功能障碍的临床分析及意义
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     The time of operations of control group was 201.33±48.09min. The loss of blood was 1640±569.21ml. Six cases have complications after operation.
     对照组手术时间为201.33±48.09min,出血量为1640±569.21ml,有2例骶神经损伤,3例出现局部皮肤缺血性疼痛,1例出现阴茎勃起功能障碍
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     ①Average PE time of PED patients with stagnation of liver and renal deficiency was shorter than that of PED patients with syndrome of blood stasis and patients in the control group (P < 0.05), so were the Porst grades and bilateral peak velocity at systolic phase (P < 0.05).
     ①肝郁证和肾虚证阴茎勃起功能障碍患者平均阴茎勃起时间明显短于血瘀证型和对照组(P<0.05),Porst分级、双侧收缩期最大血流速度明显高于血瘀证型和对照组(P<0.05)。
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  erectile dysfunction
No relationship was found between neurophysiological abnormalities and the presence or severity of erectile dysfunction, showing that these tests have little diagnostic usefulness in MS patients with impotence.
      
Acute motor axonal neuropathy presenting with bowel, bladder, and erectile dysfunction
      
Erectile dysfunction (ED) has been classified as psychogenic, arteriogenic, neurogenic, endocrinologic, and cavernosal, based on the organs that are involved in penile erection.
      
In PD patients, the prevalence of orthostatic dizziness, bladder dysfunction, erectile dysfunction and hyperhidrosis was significantly higher compared with controls.
      
The measurement of nocturnal erections has gained clinical relevance for the diagnosis of erectile dysfunction because it allows an objective and quantitative assessment of the erectile capacity.
      
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Effect of 5 kinds of α-adrenoceptor antagonist on contractile response of the rabbit penile corpus cavernosum was studied by using functional study. The results showed that the competitive effect of prazosin was the strongest among the five agents, followed by tamsulosin. No significant effect was found with phentolamine, terazosin and yohimbine. The results provide experiment basis for selecting and appling α-adrenoceptor antagonists in the treatment of penile erectile dysfunction.

本文采用离体组织收缩功能实验,比较了5种α-肾上腺素受体(α-AR)拮抗剂对去甲肾上腺素(NE)介导的兔阴茎海绵体收缩效应的影响,结果显示,哌唑嗪的拮抗作用最强,其次为tamsulosin。酚妥拉明,特拉唑嗪和育亨宾无显著拮抗作用。本实验结果为临床选用α-AR拮抗剂治疗阴茎勃起功能障碍提供了实验依据。

Objective To study the ultrastructure of cavernous tissue in impotent rats with diabetes mellitus (DM). Methods Sprague Dewley rats were injected intraperitoneally with streptozotocin(STZ) to make experimental models of DM.Injected with apomorphine,penile erections in rats with DM and in controls were observed and noted on the sixth week,the eighth week and the twelfth week from the fourth day of injecting STZ.The experimental models of impotent rats with DM were then selected and the ultrastructure of the...

Objective To study the ultrastructure of cavernous tissue in impotent rats with diabetes mellitus (DM). Methods Sprague Dewley rats were injected intraperitoneally with streptozotocin(STZ) to make experimental models of DM.Injected with apomorphine,penile erections in rats with DM and in controls were observed and noted on the sixth week,the eighth week and the twelfth week from the fourth day of injecting STZ.The experimental models of impotent rats with DM were then selected and the ultrastructure of the cavernous tissues studied. Results The significant pathological changes were observed in the endothelial and smooth muscle cells of cavernous tissue of impotent rats with DM:these were the degeneration of mitochondria,the dilatation of endoplasmic reticulum,the reduce of glycogen particle,pinocytotic vesicle and microfilament.The proliferation of messenchymal tissue and obturation of microvessel were also observed.The change extent of cavernous tissue was positively correlated with the duration of DM,the changes of endothelial and smooth muscle cells being obvious on the eight or twelve week. Conclusions The function of penile erection is affected seriously by DM,and these pathological changes of cavernous tissue may be one of the most important mechanisms of impotence with DM.

目的 探讨糖尿病(DM) 性阴茎勃起功能障碍(ED) 的发病机理。 方法 SD 大鼠注射链脲佐菌素制造DM 动物模型后,注射阿朴吗啡观察6 周、8 周及12 周大鼠阴茎勃起情况,筛选DM 性ED 大鼠模型,观察其阴茎海绵体组织超微结构的改变。 结果 DM 性ED 大鼠模型阴茎海绵体内皮细胞及平滑肌细胞超微结构均有明显的病理改变:线粒体退变、内质网扩张,糖原颗粒、吞饮小泡及微丝减少。此外,还可见大量间质组织增生及微血管腔闭塞。随DM 病程不同,其改变程度不同,8 周时以内皮细胞损害为明显,12 周时以平滑肌细胞损害为明显。 结论 DM 严重影响阴茎勃起功能,海绵体组织超微结构的病理改变可能是DM 性ED 发病机理之一。

Sildenafil is the first oral therapeutic agent for erectile dysfunction. Sildenafil is a selective inhibitor of cGMP specific phosphodiesterase (PDE 5). Penile erection involves relaxation of the corpus cavernosum, an event mediated by NO and cGMP. The biological actions of cGMP are terminated by phosphodiesterase enzymes and PDE 5 is the major cGMP metabolising enzyme in this tissue. Sildenafil is relatively safe compared to erection injectables because it does not relax on isolated human corpus cavernosum,...

Sildenafil is the first oral therapeutic agent for erectile dysfunction. Sildenafil is a selective inhibitor of cGMP specific phosphodiesterase (PDE 5). Penile erection involves relaxation of the corpus cavernosum, an event mediated by NO and cGMP. The biological actions of cGMP are terminated by phosphodiesterase enzymes and PDE 5 is the major cGMP metabolising enzyme in this tissue. Sildenafil is relatively safe compared to erection injectables because it does not relax on isolated human corpus cavernosum, and does not cause priapism. Due to the tendency of abuse of sildenafil, its adverse cardiovascular associations with myocardial infaraction, ventricular arrhythmia and hypertension need to be alerted.$Key words sildenafil; sexual dysfunction; phosphodiesterase enzyme 5 was no remarkable difference between the two methods ( P >0 05) CONCLUSION: The sugarcoat had no effect on the determination of verapamil hydrochloride tablets

西地那非(俗名伟哥)是一种治疗阴茎勃起功能障碍的口服药物,其疗效约为70%~80%。阴茎勃起功能障碍的主要原因是阴茎海绵体供血不足,可能与缺少一氧化氮(NO)有关。NO可使鸟苷酸环化酶(GC)活化,在活化的GC作用下,鸟苷酸(GTP)转变成环鸟苷酸(cGMP);cGMP可被磷酸二脂酶(PDE)降解为5′-cGMP,后者无生物学效应,而cGMP则可引起阴茎海绵体平滑肌血管舒张,使阴茎迅速充血而勃起。研究表明,西地那非可抑制PDE的作用,使cGMP聚集,从而发挥其治疗作用。然而,目前也有关于用药不当致死的病例,美国已有69例(老年人占90%以上)因服用西地那非而致死的报告。本文仅就西地那非药理作用机制作一简要介绍。

 
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