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   e-钙粘附素基因 的翻译结果: 查询用时:0.107秒
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e-钙粘附素基因
相关语句
  e-cadherin gene
     Relationship between polymorphism of E-cadherin gene and genetic susceptibility of non-cardia gastric cancer
     E-钙粘附素基因多态性与胃癌遗传易感性
短句来源
     Conclusion The C→160a promoter polymorphism of E-cadherin gene may not play a major role in the etiology of non-cardia gastric cancer.
     结论E-钙粘附素基因(CDH1)启动子区-160C→A多态性与胃癌遗传易感性不相关。
短句来源
     Objective To test the hypothesis that a C to A variant in promoter of E-cadherin gene,which is associated with risk of developing non-cardia gastric cancer.
     目的探讨E-钙粘附素基因(CDH1)启动子区-160 C→A多态性与胃癌遗传易感性的关系。
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  “e-钙粘附素基因”译为未确定词的双语例句
     Dysfunction of E-cadherin due to mutation of CDH1 was also found in diffuse-type gastric cancer.
     近年来研究发现E-钙粘附素基因(CDH1)突变与家族性胃癌的发生相关。
短句来源
  相似匹配句对
     Relationship between polymorphism of E-cadherin gene and genetic susceptibility of non-cardia gastric cancer
     E-粘附素基因多态性与胃癌遗传易感性
短句来源
     4 new genes were obtained.
     U基因
短句来源
     Expression of Epithelial cadherin in laryngeal squa- mous cell carcinoma
     喉癌E-粘附素蛋白表达
短句来源
     Expression and significance of E-cadherin in human endometriosis
     子宫内膜异位症依赖粘附素E的表达及意义
短句来源
     A Study of the Relationship between the Expression of Connexin43、E-cadherin and Biological Behaviors of Human Laryngeal Cancer
     间接连接蛋白基因Cx43和E-粘附素的表达与喉癌生物学行为关系的研究
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  e-cadherin gene
In conclusion, the decreased expression of the E-cadherin-catenin complex and methylation of the E-cadherin gene promoter region only in GH cell adenomas with prominent fibrous bodies may be an event associated with the formation of fibrous bodies.
      
Germline mutations of the E-cadherin gene (CDH1) are involved in the tumorigenesis of hereditary diffuse gastric cancer (HDGC).
      
The utility of this technique is demonstrated by PCR amplification and sequencing of the E-cadherin gene, which codes for a homophilic cell-to-cell adhesion molecule, in early gastric carcinomas of the diffuse type of Lauren's classification.
      
Preventive gastrectomy in patients with gastric cancer risk due to genetic alterations of the E-cadherin gene defect
      
In lobular breast cancer, loss of immunoreactivity has been shown to be due either to out-of-frame deletions or to nonsense mutations of the E-cadherin gene.
      
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Objective To test the hypothesis that a C to A variant in promoter of E-cadherin gene,which is associated with risk of developing non-cardia gastric cancer.Methods Population based case-control study was used and the polymerase chain reaction-restriction fragment length polymorphisms(PCR-RFLP) was used to genotype this variant in 207 non-cardia gastric cancer patients and 270 age-sex frepuencymatched cancer-free controls.Results The distributions of CDH1 genotypes were not significantly different between cases...

Objective To test the hypothesis that a C to A variant in promoter of E-cadherin gene,which is associated with risk of developing non-cardia gastric cancer.Methods Population based case-control study was used and the polymerase chain reaction-restriction fragment length polymorphisms(PCR-RFLP) was used to genotype this variant in 207 non-cardia gastric cancer patients and 270 age-sex frepuencymatched cancer-free controls.Results The distributions of CDH1 genotypes were not significantly different between cases and controls(χ~2=0.29,P=0.87).Compared with the CC genotype,the variant CA and AA genotypes were not associated with an increased risk of gastric cancer [adjusted odds ratio(ORa) were 1.15,0.90 respectively;95% confidence interval(CI) were 0.87-1.72,0.42-2.01 respectively].Conclusion The C→160a promoter polymorphism of E-cadherin gene may not play a major role in the etiology of non-cardia gastric cancer.

目的探讨E-钙粘附素基因(CDH1)启动子区-160 C→A多态性与胃癌遗传易感性的关系。方法应用以人群为基础的病例对照研究,采用聚合酶链反应-限制性片段长度多态性(PCR-RFLP)技术检测胃癌病例组与健康对照组的-160C→A多态改变的频率。结果CDH1-160C→A多态改变在胃癌病例组中的频率分别是CC型为57.8%、CA型为36.4%、AA型为5.8%,对照组各型频率分别是CC型为58.2%、CA型为34.9%、AA型为6.9%。调整年龄、性别、地区、吸烟、饮酒、饮茶、H.pylori感染以及胃癌家族史等因素后,CDH1各基因型在2组间差异均无统计学意义(χ2=0.29,P=0.87);将CA基因型与AA基因型合并后进行病例组与对照组之间的比较,差异无统计学意义(χ2=0.01,P=0.92)。结论E-钙粘附素基因(CDH1)启动子区-160C→A多态性与胃癌遗传易感性不相关。

 
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