Objective To investigate the influence of recombined human growth hormone(rHGH) on the growth hormone(GH) and insulin-like growth factor(GH-IGF) axes in the patients with chronic severe viral hepatitis(CSVH).
目的研究重组人生长激素(rHGH)对慢性重型病毒性肝炎(chronic severe viral hepatitis,CSVH)患者生长激素(growth hormone,GH)-胰岛素样生长因子(insulin-like growth factor,GH-IGF)轴的变化以及其影响。
Objective To analyze the acquirement of nutrient and the statement of malnutrition in patients with chronic severe viral hepatitis and to direct the nutritional evaluation and the nutritional support in treatment to enhance survival rate.
Methods: 46 cases of viral chronic severe hepatitis with hyponatremia and ascites were supplied with sodium, and the changes of concertration of sodium in blood,ascites, urine and its volume were observed during 24 hours.
Objective To investigate whether there is a correlation of serum interleukin 18 (IL 18) and nitric oxide (NO) with Fulminant Hepatic Failure(FHF) and the effect of N acetylcysteine (NAC) on IL 18 and NO levels.
Methods The clinical data of 391 patients with chronic severe hepatitis among 2003～2005 in our hospital were analyzed,and they were graded with MELD formula. These patients were divided into plasma exchange group and none plasma exchange group according to plasma exchange treatment or not. The death rate was observed within three months.
56 cases of biopsy proved subacute and chronic severe viral hepatitis are analysed. It showed that the serum bilirubin and the degree of prothrombin activity were important prognostic factors. The prognosis of the subacute severe types were better than that of chronic severe types. When fall of blood oxygen pressure and the degree of prothrombin activity appeared, one should watch out for subacute liver necrosis. Early diagnosis and prompt treatment might increase survival.The pathological recovery was later...
56 cases of biopsy proved subacute and chronic severe viral hepatitis are analysed. It showed that the serum bilirubin and the degree of prothrombin activity were important prognostic factors. The prognosis of the subacute severe types were better than that of chronic severe types. When fall of blood oxygen pressure and the degree of prothrombin activity appeared, one should watch out for subacute liver necrosis. Early diagnosis and prompt treatment might increase survival.The pathological recovery was later than that of clinical symptoms and the laboratory finding improvements.Some of the cases had converted into chronic aggressive hepatitis or cirrhosis of liver in the 3rd or 4th months of the disease.
The plasma and urinary lipid peroxides (LPO)levels were measured by fluorometric assay in 38 patients with chronic severe viral hepatitis(CSVH), 22 patients with acute hepatitis (AH)and 20 healthy controls. The levels of plasma cyclic nucleotide, prostacyclin(PGI_2) and thromboxane A_2(TXA_2) were simultaneously meassured by RIA in patients with CSVH. The results showed that: 1. In comparision with AH and controls, the plasma and urinary LPO levels in patients with CSVH were significantly elevated(P<0.01). 2....
The plasma and urinary lipid peroxides (LPO)levels were measured by fluorometric assay in 38 patients with chronic severe viral hepatitis(CSVH), 22 patients with acute hepatitis (AH)and 20 healthy controls. The levels of plasma cyclic nucleotide, prostacyclin(PGI_2) and thromboxane A_2(TXA_2) were simultaneously meassured by RIA in patients with CSVH. The results showed that: 1. In comparision with AH and controls, the plasma and urinary LPO levels in patients with CSVH were significantly elevated(P<0.01). 2. In patients with CSVH, the plasma LPO levels were positively related to plasma TXA_2 and urinary LPO, and negatively related to PGI_2 and cAMP. The important role of lipid peroxidation in hepatic injury were discussed.
慢性重型病毒性肝炎
chronic severe viral hepatitis
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