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rb蛋白     
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  rb protein
     Purpose To study the expression of human papilloma viruses 16 and 18 (HPV16/18) DNA and the cell cycle proteins of p16~ Ink4a and Rb in cervical adenocarcinoma and the influence of HPV16/18 infection on expressions of p16~ Ink4a and Rb protein.
     目的研究16、18型人乳头瘤病毒(HPV16/18)DNA与细胞周期相关蛋白p16Ink4a、Rb在子宫颈腺癌中的表达情况及HPV16/18感染对p16Ink4a、Rb蛋白表达的影响。
短句来源
     Expression of cyclin D1 and Rb protein in breast cancer
     乳腺癌cyclin D1、Rb蛋白表达的意义
短句来源
     Expression of Rb protein was identified in 60.9%of patients, and correlate d with clinical grades(P< 0.05).
     Rb蛋白的阳性表达率为60.9%,与临床分级相关(P<0.05)。
短句来源
     The results indicated that the expression rates of p16 and Rb protein were 37.5%(12/32) and 56.3%(18/32) respectively.
     结果显示,p16和Rb蛋白阳性表达分别为37.5%(12/32)和56.3%(18/32)。
短句来源
     In endometrial carcinoma, the expressions of p16 and Rb protein were positively correlated( r=0.42, P < 0.01), while rasp21 and ER, PR were inversely correlated( r=-0.46, -0.42 ;P <0.01).
     子宫内膜癌组织中,p16与Rb蛋白的表达呈正相关(r=0.42,P<0.01),rasp21蛋白与ER、PR的表达呈负相关(r=-0.46、-0.42,P<0.01)。
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  rb proteins
     Influence of HPV16/18 infection on expressions of p16~(Ink4a) and Rb proteins in adenocarcinoma of cervix
     子宫颈腺癌中HPV16/18感染对p16~(Ink4a)、Rb蛋白表达的影响
短句来源
     Aberrant expression of p53、BRCA1、BRCA2、PTEN、Rb proteins in breast cancer development
     乳腺癌发生过程中p53、BRCA1、BRCA2、PTEN、Rb蛋白异常表达
短句来源
     Study on the Roles of HSP70, Rb Proteins and HPV16E7 Proteins in the Pathogenesis of Human Laryngeal Carcinoma
     HSP70、Rb蛋白、HPV16E7蛋白在人喉癌发生中作用的研究
短句来源
     The Expression of c-Myc, CyclinE and CyclinD_1, Rb Proteins in Breast Carcinoma
     乳腺癌中c-Myc、cyclinE及cyclinD1、Rb蛋白的表达及其意义
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     Expression of P16 and Rb Proteins in Gastric Carcinoma
     胃癌中P16、Rb蛋白表达分析
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  retinoblastoma protein
     Expression of Retinoblastoma Protein during Apoptosis of Glioma Cell
     Rb蛋白在胶质瘤细胞凋亡中的表达
短句来源
     to determine the content of the retinoblastoma protein and the phosphorylase Rb protein of cells by ELISA method;
     ELISA法检测细胞总视网膜母细胞瘤蛋白 (Rb)和磷酸化Rb蛋白的含量;
短句来源
     Effect of sodium selenite on phosphorylation of retinoblastoma protein of human promyelocytic leukemia cells (HL-60)
     亚硒酸钠对人早幼粒白血病细胞的RB蛋白磷酸化的影响
短句来源
     The Clinical Implication of Retinoblastoma Protein Expression in Multiple Myeloma
     Rb蛋白在多发性骨髓瘤细胞中的表达及临床意义
短句来源
     Methods A549 cell line was transfected with p16 INK4A and the stably transfected strain was identified with Northern blot and Southern blot. Cell cycle was analysied by flow cytometry. The phosphorylation state of retinoblastoma protein(Rb) and cell phenotype were determined by Western blot and SA-β-gal staining.
     方法 用pcDNA3 p16质粒转染 p16基因缺失的A5 4 9肺小细胞腺癌细胞系并通过Northernblot和Westernblot鉴定 p16基因的异位表达 ,通过流式细胞仪分析转染后细胞周期变化 ,利用Westernblot和SA β gal染色检测Rb蛋白磷酸化状态的改变和细胞表型变化。
短句来源
  rb gene protein
     Rb gene protein positive expression rate in tumor tissues was 51.4%,which was also lower than that in normal mucosal tissues of colon and rectum (χ2=4.234,P< 0.05); Rb protein positive expression correlated significantly with lymph node metastasis(χ2=14.596, P< 0.05), but did not correlated with tumor cell differentiation( P >0.05).
     Rb蛋白阳性表达率在大肠腺癌组织中为51.4%,显著低于正常大肠黏膜组织(χ2=4.234,P<0.05),并与大肠腺癌淋巴结转移有关(χ2=14.596,P<0.05),但与组织分化程度无关(P>0.05);
短句来源
     Objective: To detemine the relationship between the expression of MTS1/p16, p53, Rb gene protein or proliferating cell nuclear antigen( PCNA) and clinicopathologic of human gastric cancer.
     目的:研究胃癌中 p16、 p53、 Rb蛋白及 PCNA表达与临床病理的关系。 方法:应用免疫组化 SP法对 63例胃癌组织中 p16、 p53、 Rb和 PCNA进行检测。
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  rb protein
Expression of p16, cyclin D1 and RB protein in gastric carcinoma and premalignant lesions
      
Objective: To investigate the expression of p16, cyclin D1 and Rb protein in gastric carcinoma and premalignant lesions including dysplastic gastric mucosa and intestinal metaplasia gastric mucosa.
      
Expression of Rb protein was detected in 90% of normal gastric mucosa, 80% of dysplastic gastric mucosa, 80% of intestinal metaplasia gastric mucosa, 50% of gastric carcinoma.
      
The positive rate of Rb protein expression in gastric carcinoma is significantly lower than that in normal gastric mucosa (P>amp;lt;0.05).
      
This was mediated by the Rb pathway, as shown by an E2F1-driven reporter assay and Western immunoblot of phosphorylated Rb protein.
      
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  rb proteins
Methods: We performed Western blot analysis of five cell-cycle stimulating (cyclins D1, E, B1, cdk2, cdk4) and three cell-cycle inhibiting (p16INK4a, p21WAF1, Rb) proteins in 41 endometrial carcinoma specimens.
      
Expression of p53 and RB Proteins in Squamous Cell Carcinoma of the Esophagus: Their Relationship With Clinicopathologic Charact
      
In cl-2 cells in semisolid culture, DEX suppressed the expression of P27Kip1, whereas it stimulated the expression of cyclin A and hyperphosphorylated retinoblastoma (Rb) proteins.
      
This review assesses the potential roles of Rb proteins in plant cell cycle control and development.
      
Similar to other types of cancer, essential pathways regulating apoptosis are also disrupted in malignant gliomas, notably the cell cycle control mechanisms regulated by the p53 and retinoblastoma (RB) proteins and their homologs.
      
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  retinoblastoma protein
The participation of RB1 was excluded in four of the five cases because retinoblastoma protein was shown to be positive in these tumors in our previous study.
      
Immunohistochemical analysis of the cell cycle-associated antigens Ki-67 and retinoblastoma protein in parathyroid carcinomas an
      
Expression of retinoblastoma protein in human growth hormone-secreting pituitary adenomas
      
Some studies have shown that losses in this chromosomal region are related to aggressive tumor behavior, although the retinoblastoma protein (pRB) is still expressed.
      
Whereas cyclin D1 is the regulatory subunit of the complex, CDK4 represents the catalytic domain that, once activated, will phosphorylate downstream targets such as the retinoblastoma protein, allowing cell-cycle progression.
      
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  rb gene protein
Gossypol plasma levels were measured (n=8) and the modulation of the retinoblastoma (Rb) gene protein and Cyclin D1 was assessed by serial biopsies (n=4).
      
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