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胃腺癌
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  stomach gland cancer
    Study of Modified San Wu Bai San on Inducing Apoptosis of Human Stomach Gland Cancer SGC-7901 Cells and the Effect of Cell Cycle
    加味三物白散诱导人胃腺癌SGC-7901细胞凋亡及对细胞周期影响的研究
短句来源
    Objective:To study Modified San Wu Bai San(MSWBS)in inhibiting effect on stomach gland cancer cells SGC-7901,inducing apoptosis of stomch gland cancer cells SGC-7901 and the influcence on cell cycle.
    目的 :观察加味三物白散对人胃腺癌SGC - 790 1细胞生长的抑制作用 ,影响细胞周期及诱导人胃腺癌SGC -790 1细胞凋亡。
短句来源
    The effect of MSWBS on DNA synthesis and Cell cycle in stomach gland cancer SGC-7901 cells were investigated with the help of flow cytometry.
    应用流式细胞仪检测加味三物白散诱导人胃腺癌SGC - 790 1细胞凋亡和对细胞周期的影响。
短句来源
    Conclusion:MSWBS obviously inhibits the growth of stomach gland cancer SGC-7901 cells,induces SGC-7901 cells apoptosis at moderate and large concentration and influence cell cycle.
    其中、大剂量组可以明显诱导人胃腺癌SGC - 790 1细胞凋亡 ; 并且加味三物白散对人胃腺癌SGC - 790 1细胞的增殖周期有影响
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  “胃腺癌”译为未确定词的双语例句
    Effect of Traditional Chinese Medicine Compounds Aining on the Expression of Apoptosis Inducing Genes of Human Gastric Cancer Cell
    中药复方癌宁对人胃腺癌细胞凋亡基因表达的影响
短句来源
    Serum-pharmacological effects of Stellera chamaejasme L. abstract with water on proliferation of gastric adnocacinoma SGC-7901 Cells
    瑞香狼毒水提物小鼠药物血清对人胃腺癌SGC-7901细胞增殖的影响
短句来源
    Results Studies in vitro found Aikangning could produce obvious cytotoxicity on BEL-7402 human hepatocellular carcinoma cell,MGC-80-3 human gastric adenocarinoma cell and Eca109 human esophageal carcinoma cell.
    结果爱康宁胶囊对人癌细胞 (肝癌BEL -74 0 2、胃腺癌MGC -80 -3和食管癌Eca1 0 9)有明显的细胞毒作用。
短句来源
    Methods: SCLA drugserum was derived after different time from mice which was orally peradministrated with different dose of SCLA. the effects of the serum on the roliferation of human gastric adnocacinoma SCG7901 cells were observed with MTT assay and clone formation methods.
    方法 :以不同剂量的SCLA灌胃给药后 ,在不同时间采集小鼠血清 ,处理体外培养的人胃腺癌SGC 790 1细胞 ,用MTT比色法和集落形成试验观察细胞增殖能力。
短句来源
    It couldn't shift the cell cluster into the G0F-G2 stage.
    小剂量组使G0 -G1期细胞明显增高 ,G2 -M期明显减少 ,S期减少。 结论 :加味三物白散能抑制人胃腺癌SGC - 790 1细胞生长 ;
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The antitumour activities of 6 natural steroidal saponins extracted from Smilax on hepatoma SMMC-7721 cell,human cervicarcinoma HeLa cell and human gastric adenocarcinoma. MGc80-3 cell vs well known antitumour drug, vincristine (VCR),were studied using the MTT colorimetric assay. The results showed that the antitumour effects of 6 steroidal saponins were related both to their chemical structures and to tumour cell lines susceptibities to tested compounds. The antitumour effects ranked as dioscin>VCR>DQD4>SQD3>M1>SQD1,methyl...

The antitumour activities of 6 natural steroidal saponins extracted from Smilax on hepatoma SMMC-7721 cell,human cervicarcinoma HeLa cell and human gastric adenocarcinoma. MGc80-3 cell vs well known antitumour drug, vincristine (VCR),were studied using the MTT colorimetric assay. The results showed that the antitumour effects of 6 steroidal saponins were related both to their chemical structures and to tumour cell lines susceptibities to tested compounds. The antitumour effects ranked as dioscin>VCR>DQD4>SQD3>M1>SQD1,methyl protodioscin. The steroidal structure of these steroidal saponins was the decisive factor for their antitumour activities.

采用MTT法,以长春新碱(VCR)为阳性对照,研究了6种从菝葜属植物中分离提取的天然甾体皂甙化合物对肝癌SMMC-7721、人宫颈癌HeLa和胃腺癌MGc80-3细胞生长的抑制作用.结果显示;6种甾体皂甙抗肿瘤活性与其化学结构密切相关,对三种癌细胞的抑瘤作用强度相同,抑癌活性的顺序为:薯蓣皂甙>VCR>SQD_4>SQD_3>M_1>SQD_1,甲基原薯蓣皂甙.甾体骨架的差异性是决定这类化合物抗肿瘤活性的主要因素.

To study the cytotoxic activity of bufalin, one of the components of bufadienolides in the TCM “Chansu”, and its mechanism of act ion. Human gastric cancer cell line MGc-803 was used as target cells. Inhibition of t umor cell growth was assessed by trypan blue exclusion and thiazole blue absorba nce and light microscope examination. Result showed that bufalin at concentrati ons of 0.01 μ mol/L and above could remarkably inhibit the growth of MGc-803 t um or cell, with IC50 of about 0.1 μ mol/L. Further study...

To study the cytotoxic activity of bufalin, one of the components of bufadienolides in the TCM “Chansu”, and its mechanism of act ion. Human gastric cancer cell line MGc-803 was used as target cells. Inhibition of t umor cell growth was assessed by trypan blue exclusion and thiazole blue absorba nce and light microscope examination. Result showed that bufalin at concentrati ons of 0.01 μ mol/L and above could remarkably inhibit the growth of MGc-803 t um or cell, with IC50 of about 0.1 μ mol/L. Further study showed that its mechanism of action involved necrotic changes of nuclear chromatin and fragmentati on of chromosomal DNA leading to cell death.

蟾蜍灵(bufalin)是我国传统中药蟾酥中蟾毒的主要成分之 一,研究其抑癌作用及机制具有重要意义。采用台盼蓝染色法、噻唑蓝还原法和光镜观察bu falin对人低分化胃腺癌细胞系MGc-803的生长抑制作用。结果显示,0.01 μmol/L及以上 浓度bufalin对MGc-803细胞具有显著的抑制作用,IC50值约为0.1 μmol/L。bufal in抑制MGc-803生长的机制是致使细胞核染色质凝缩、碎裂,DNA损伤,胞浆RNA含量下降, 导致细胞死亡。

Objective To study the cancer-fighting activity in vitro and toxicity of Aikangning Capsules.Methods The cancer-fighting activity were observed by agar plate method and the toxcity by acute maximal tolerance dose toxicity testing.Results Studies in vitro found Aikangning could produce obvious cytotoxicity on BEL-7402 human hepatocellular carcinoma cell,MGC-80-3 human gastric adenocarinoma cell and Eca109 human esophageal carcinoma cell.LD50 of Aikangning on mice for intraperitoneal administration was 39.8±4.5g/kg.The...

Objective To study the cancer-fighting activity in vitro and toxicity of Aikangning Capsules.Methods The cancer-fighting activity were observed by agar plate method and the toxcity by acute maximal tolerance dose toxicity testing.Results Studies in vitro found Aikangning could produce obvious cytotoxicity on BEL-7402 human hepatocellular carcinoma cell,MGC-80-3 human gastric adenocarinoma cell and Eca109 human esophageal carcinoma cell.LD50 of Aikangning on mice for intraperitoneal administration was 39.8±4.5g/kg.The acute maximal tolerance dose toxicity testing found that Aikangning (600mg/kg·d po ×7) didn't show obvious toxicity on mice.Conclusion Aikangning Capsules could produce obvious cancer-fighting effects by killing cancerous cell directly,showing less toxicity.

目的观察爱康宁胶囊体外抗肿瘤活性及毒副作用。方法采用双层琼脂集落形成实验观察爱康宁胶囊的体外抗癌作用 ,并作急性毒性限量实验观察爱康宁胶囊的毒性作用。结果爱康宁胶囊对人癌细胞 (肝癌BEL -74 0 2、胃腺癌MGC -80 -3和食管癌Eca1 0 9)有明显的细胞毒作用。小鼠腹腔注射LD50 为 39.8± 4 .5 g/kg ,急性毒性限量试验小鼠口服 6 0 0 g/kg·d ,连用 7d ,无明显毒性。 结论爱康宁胶囊可通过直接杀灭癌细胞而发挥显著的抗肿瘤作用 ;对机体毒性小。

 
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