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胃腺癌
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  “胃腺癌”译为未确定词的双语例句
    THE BIOLOGICAL EFFECTS OF EXOGENOUS ATP ON HUMAN STOMACH GLANDULAR CANCER CELLS (SGC-7901)
    外源性三磷酸腺苷对人胃腺癌SGC-7901细胞的生物学效应
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    Helicobacter pylori is an important bacterial pathogen that causes chronic active gastritis and is associated with gastroduodenal ulcer disease, adenocarcinoma of the distal stomach, and gastric lymphoma in humans.
    幽门螺杆菌(Helicobacter pylori,H.pylori)是导致人类发生慢性活动性胃炎、消化性溃疡的主要病原菌,并且与胃腺癌、胃粘膜相关淋巴组织淋巴癌的发生也密切相关。
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    Helicobacter pylori(Hp), a gram-negative spiral bacterium, is the major etiological factor of chronic active gastisis and most peptic ulcer disease, and is closely associated with gastric cancer tumors such as adenocarcinoma and MALT lymphoma.
    幽门螺杆菌(Helicobacter pylori,Hp)是一种革兰氏阴性菌、呈螺旋形,是引起人发生慢性活动性胃炎、胃和十二指肠溃疡的主要病原菌,同时与胃腺癌、胃粘膜相关淋巴组织淋巴瘤(MALT)的发生也密切相关。
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    Exogenic cAMP and theophylline would elevate the intracellular content of cAMP,and the regression of microvilli and reduction of ATPase activity may indicate the reversion of the cancer cell.
    同时见到细胞膜表面上的 Na~+—K~+—ATP 酶活性受到抑制。 本文讨论了外源性 cAMP 对人胃腺癌 SGC-7901细胞系增殖的抑制作用,以及膜表面微绒毛和Na~+—K~+—ATP 酶活性变化的关系。
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    An ultrastructural study of the myofibroblasts was made in 30 gastro--adenocarcinomas and 10 breast carcinomas. The results showed that there were 3 types of myofibroblasts.
    本文观察了30例胃腺癌和10例乳腺癌间质中肌成纤维细胞的超微结构。
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To cell culture medium of human stomach glandular carcinoma,cell line SGC-7901, 1mmol/L of cAMP and 1 mmol/L theophylline was added,The growth rates of the cultured cell was obviously depressed,SEM observation showed the regression of microvilli on the cell surface,and at the same time,TEM observation showed a mark reduction of Na~+-K~+ -ATPase activities. Exogenic cAMP and theophylline would elevate the intracellular content of cAMP,and the regression of microvilli and reduction of ATPase activity may indicate...

To cell culture medium of human stomach glandular carcinoma,cell line SGC-7901, 1mmol/L of cAMP and 1 mmol/L theophylline was added,The growth rates of the cultured cell was obviously depressed,SEM observation showed the regression of microvilli on the cell surface,and at the same time,TEM observation showed a mark reduction of Na~+-K~+ -ATPase activities. Exogenic cAMP and theophylline would elevate the intracellular content of cAMP,and the regression of microvilli and reduction of ATPase activity may indicate the reversion of the cancer cell.

本实验通过外源性 cAMP 和茶碱对人胃腺癌细胞系 SGC-7901的连续作用,观察到外源性 cAMP 和茶碱对该细胞株的增殖,具有明显的抑制作用。在透射电镜和扫描电镜下,均可见到细胞表面较光滑,微绒毛减少或消失。同时见到细胞膜表面上的 Na~+—K~+—ATP 酶活性受到抑制。本文讨论了外源性 cAMP 对人胃腺癌 SGC-7901细胞系增殖的抑制作用,以及膜表面微绒毛和Na~+—K~+—ATP 酶活性变化的关系。

The experiment was carried out on cultured human stomach glandular carcinoma (SGC-7901 cell line). We previously reported the cytochemical changes of (Na~+-K~+)-ATPase activity and the changes of microvilli. We here studied the relationship among the cAMP, cAMP-PDEase, Mg~(++)-ATPase activity, the cell growth and differentiation. Cells were exposed to Immol/L cAMP together with 1 mmol/L theophylline. We showed cAMP specific fluorescence by immunocytochemical method, Mg~(++)-ATPase and cAMP-PDEase activity by...

The experiment was carried out on cultured human stomach glandular carcinoma (SGC-7901 cell line). We previously reported the cytochemical changes of (Na~+-K~+)-ATPase activity and the changes of microvilli. We here studied the relationship among the cAMP, cAMP-PDEase, Mg~(++)-ATPase activity, the cell growth and differentiation. Cells were exposed to Immol/L cAMP together with 1 mmol/L theophylline. We showed cAMP specific fluorescence by immunocytochemical method, Mg~(++)-ATPase and cAMP-PDEase activity by cytochemical methods. We found that cAMP with theophylline not only inhibited the growth of these SGC-7901 cells as shown by our previous result, but also decreased the activity of Mg~(++)-ATPase and 3', 5'-cyclic monophosphate phosphodiesterase. The result indicates that exogenous cAMP can inhibit 3', 5'-cAMP-PDEase and Mg~(++)-ATPase activity and increase cAMP level in cell, and cAMP regulated the growth and differentiation of SGC-7901 cell line

本实验通过外源性3′,5′环腺苷酸(cAMP)对人胃腺癌SGC-7901细胞系的连续作用,观察到癌细胞的增殖受到明显抑制的同时,膜表面环腺苷酸-磷酸二酶(cAMP-PDEase)的活性及Mg~(++)-ATPase活性均明显下降,而细胞内cAMP免疫荧光强度则明显增强,进一步证实了细胞内cAMP水平与细胞的生长、分化,及膜表面ATPase、cAMP-PDEase的活性有密切的关系。

This experiment was carried out on the SGC-7901 cell line in vitro. On the second day of plating, ATP (0.32mg/ml) was added into the culture medium as the experiment group and in the control group only changed the culture medium.The cAMP-PDEase activity and cellular surface feature were observed by electron microscope and scanning electron microscope. The intracellular fibronectin and cAMP were demonstrated by immunocytochemistry method.We have found that ATP not only could inhibit the proliferation of SGC-7901...

This experiment was carried out on the SGC-7901 cell line in vitro. On the second day of plating, ATP (0.32mg/ml) was added into the culture medium as the experiment group and in the control group only changed the culture medium.The cAMP-PDEase activity and cellular surface feature were observed by electron microscope and scanning electron microscope. The intracellular fibronectin and cAMP were demonstrated by immunocytochemistry method.We have found that ATP not only could inhibit the proliferation of SGC-7901 cells with inhibition rate over 80% after the 4th day of treatment, and decrease the activity of cAMP-PDEase as well as the regression of microvilli on the cell surface but also increase the intensity of specific fluorescence of intracellular fibronectin and cAMP.These results indicated that ATP was a potent inhibitor of cAMP-PDEase of the cell surface of human glandular cancer cell (SGC-7901). The possible mechanism which indicates that ATP might regulate the intracellular cAMP level and thus mediate proliferation and differentiation of the cells was disoussed.

本文报道外源性三磷酸腺苷(ATP)对人胃腺癌SGC-7901细胞系增殖的抑制效应。在SGC-7901细胞的培养基质内加入ATP后,细胞生长明显受阻抑,4天以后,抑制率可达80%以上;癌细胞质膜上的3′,5′环腺苷酸磷酸二酯酶(cAMP-PDEase)活性明显下降,而细胞内的cAMP和纤维粘连蛋白的免疫荧光强度却明显增强。癌细胞多呈梭形,微绒毛减少,表面较光滑,呈现癌细胞向正常方向逆转的表型特征。本文还就ATP作用的机理进行了讨论。

 
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