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治疗性血管生成
相关语句
  therapeutic angiogenesis
    Vascular Endothelial Growth Factor for Therapeutic Angiogenesis:Problems and Potential Solutions
    血管内皮生长因子用于治疗性血管生成的问题及对策
短句来源
    The Role of Perlecan in Therapeutic Angiogenesis of Coronary Heart Disease and Its Signalling Pathway
    串珠素在冠心病治疗性血管生成中的作用及其信号转导机制研究
短句来源
    Therapeutic angiogenesis is a promising new method for the treatment of ischemic heart disease, and in recent years,implantation of autologous bone marrow cells has opened up a new pathway to such object and is now attracting many researchers' attentiion.
    治疗性血管生成是治疗缺血性心脏病的新方法,而自体骨髓细胞移植为血管生治疗开辟了新的途径并受到广泛的关注。
短句来源
    The novel methods in recent advances for those include targeting the vascular injuries,therapeutic angiogenesis,protective and restorative the myocardial function,regeneration and repair of cell or tissue,targeting the gene,cell cycle machinery and primary of the diseases related with cardiovascular lesions,and the prevention and treatment of restenosis after coronary stenting.
    具体措施是:靶向治疗血管病变、治疗性血管生成、心肌保护性治疗、细胞或组织的再生与修复、靶向致病基因的治疗、靶向细胞周期的治疗、靶向治疗导致心血管病变的原发病、冠状动脉再狭窄的预防与治疗等。
短句来源
    The concept of therapeutic angiogenesis is defined in recent years.
    治疗性血管生成是近年来提出的新概念。
短句来源
  therapeutic angiogenesis
    Vascular Endothelial Growth Factor for Therapeutic Angiogenesis:Problems and Potential Solutions
    血管内皮生长因子用于治疗性血管生成的问题及对策
短句来源
    The Role of Perlecan in Therapeutic Angiogenesis of Coronary Heart Disease and Its Signalling Pathway
    串珠素在冠心病治疗性血管生成中的作用及其信号转导机制研究
短句来源
    Therapeutic angiogenesis is a promising new method for the treatment of ischemic heart disease, and in recent years,implantation of autologous bone marrow cells has opened up a new pathway to such object and is now attracting many researchers' attentiion.
    治疗性血管生成是治疗缺血性心脏病的新方法,而自体骨髓细胞移植为血管生治疗开辟了新的途径并受到广泛的关注。
短句来源
    The novel methods in recent advances for those include targeting the vascular injuries,therapeutic angiogenesis,protective and restorative the myocardial function,regeneration and repair of cell or tissue,targeting the gene,cell cycle machinery and primary of the diseases related with cardiovascular lesions,and the prevention and treatment of restenosis after coronary stenting.
    具体措施是:靶向治疗血管病变、治疗性血管生成、心肌保护性治疗、细胞或组织的再生与修复、靶向致病基因的治疗、靶向细胞周期的治疗、靶向治疗导致心血管病变的原发病、冠状动脉再狭窄的预防与治疗等。
短句来源
    The concept of therapeutic angiogenesis is defined in recent years.
    治疗性血管生成是近年来提出的新概念。
短句来源
  “治疗性血管生成”译为未确定词的双语例句
    Vascular endothelial growth factor(VEGF) is one of the most important genes in the stratefy because of its traits in angiogenesis.
    血管内皮细胞生长因子因为其强大的促进新血管形成的作用,使其在“治疗性血管生成”中成为研究热点。
短句来源
    The researcher studied replacing CABG and PTCA with rehabilitate blood vessel,and angiopoiesis by using TMLP and vessel endothelia growth factor is most emergent.
    一方面 ,研究者探索替代冠状动脉搭桥术 (CABG)和经皮腔内冠状动脉成形术 (PTCA)的血管重建治疗 ,其中以激光心肌血管重建术 (TMLR)和血管内皮生长因子 (VEGF)治疗性血管生成的研究和运用最为突出。
短句来源
    The combined insertion of different gene constructs into single cells and their progeny allows the simultaneous expression of different 'growth' and 'maturation' factors within the same cell.
    导入不同基因到同一细胞以获得能同时表达“生长”和“成熟”因子的细胞,使细胞介导的基因转移在治疗性血管生成中具有独特价值。
短句来源
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  therapeutic angiogenesis
Therapeutic angiogenesis improves tissue ischemia by
      
New revascularization modalities such as therapeutic angiogenesis need to be matched by sensitive imaging tools to prove their benefits.
      
Thus, the optimization of therapeutic angiogenesis may profit from the diagnostic advantages provided by MR perfusion imaging.
      
From therapeutic angiogenesis to myocardium regeneration
      
Preclinical studies have documented that gene transfer of plasmid DNA encoding for secreted angiogenic cytokines such as vascular endothelial growth factor (VEGF) can induce therapeutic angiogenesis in animal models.
      
更多          
  therapeutic angiogenesis
Therapeutic angiogenesis improves tissue ischemia by
      
New revascularization modalities such as therapeutic angiogenesis need to be matched by sensitive imaging tools to prove their benefits.
      
Thus, the optimization of therapeutic angiogenesis may profit from the diagnostic advantages provided by MR perfusion imaging.
      
From therapeutic angiogenesis to myocardium regeneration
      
Preclinical studies have documented that gene transfer of plasmid DNA encoding for secreted angiogenic cytokines such as vascular endothelial growth factor (VEGF) can induce therapeutic angiogenesis in animal models.
      
更多          


Recently, the interventional therapy of ischemic cardiomyopathy has made new trends. The researcher studied replacing CABG and PTCA with rehabilitate blood vessel,and angiopoiesis by using TMLP and vessel endothelia growth factor is most emergent. The research of methods for replacing heart transplantation with cardiac muscle cell regeneration due to stem cell transplantation has begun,theirfore necroticorfibrotic cardiac muscle cells may be repaired. In this paper,above problems have been discussed.

最近 ,缺血性心肌病介入治疗研究呈现出明显的新动向。一方面 ,研究者探索替代冠状动脉搭桥术 (CABG)和经皮腔内冠状动脉成形术 (PTCA)的血管重建治疗 ,其中以激光心肌血管重建术 (TMLR)和血管内皮生长因子 (VEGF)治疗性血管生成的研究和运用最为突出。另一方面 ,在干细胞研究领域举世瞩目的背景下 ,人们开始探索以干细胞移植引起心肌再生代替心脏移植的方法 ,从而在根本上修复已坏死或纤维化的心肌细胞。本文就上述问题分别进行讨论。

Therapeutic angiogenesis is a promising new method for the treatment of ischemic heart disease, and in recent years,implantation of autologous bone marrow cells has opened up a new pathway to such object and is now attracting many researchers' attentiion.This article analyzes the cell biological base of autologous bone marrow cells and the possible mechanism of neovascularization induced by implantation of autologous bone marrow cells;in addition, the effect, safety and feasibility of the implantation of autologous...

Therapeutic angiogenesis is a promising new method for the treatment of ischemic heart disease, and in recent years,implantation of autologous bone marrow cells has opened up a new pathway to such object and is now attracting many researchers' attentiion.This article analyzes the cell biological base of autologous bone marrow cells and the possible mechanism of neovascularization induced by implantation of autologous bone marrow cells;in addition, the effect, safety and feasibility of the implantation of autologous bone marrow cells are reviewed and commented on the basis of recent researches in animal and clinical trials.

治疗性血管生成是治疗缺血性心脏病的新方法,而自体骨髓细胞移植为血管生治疗开辟了新的途径并受到广泛的关注。本文结合最近几年内的相关研究,对于骨髓细胞移植与促血管生成的有关细胞学基础、相关机制作了分析,同时对于骨髓细胞移植用于促心肌血管生成治疗的有关动物和临床实验作了回顾和评价。

Vascular endothelial growth factor (VEGF) is a major angiogenic factor involved in physiological as well as pathological angiogenesis.The ability of VEGF to promote angiogenesis in animal and clinical studies has been studied extensively.However,increasing evidence indicates that the new vasculature needs to be stabilized to avoid deleterious effects such as edema and hemangioma formation.Moreover,VEGF can promote angiogenesis but may also enhances atherosclerotic plaque progression.Mature vessels may be generated...

Vascular endothelial growth factor (VEGF) is a major angiogenic factor involved in physiological as well as pathological angiogenesis.The ability of VEGF to promote angiogenesis in animal and clinical studies has been studied extensively.However,increasing evidence indicates that the new vasculature needs to be stabilized to avoid deleterious effects such as edema and hemangioma formation.Moreover,VEGF can promote angiogenesis but may also enhances atherosclerotic plaque progression.Mature vessels may be generated by modulating timing and dosage of VEGF expression,or by combination of 'growth' factors with 'maturation' factors like platelet derived growth factor BB (PDGF-BB).Cell-mediated gene transfer has unique characteristics that make it a useful tool for therapeutic angiogenesis.The combined insertion of different gene constructs into single cells and their progeny allows the simultaneous expression of different 'growth' and 'maturation' factors within the same cell.An alternative strategy is therapy based on transcription factors.

生理和病理性血管生成中,血管内皮生长因子(vascularendothelialgrowthfactor,VEGF)是主要的血管生成因子。VEGF促血管生成的能力在动物和临床中已得到了广泛的研究。然而,越来越多的证据显示新生血管结构需要获得稳定,以避免水肿和形成血管瘤等不良反应。而且VEGF在促进血管生成的同时,也可能促进粥样斑块的生长。通过调节VEGF表达时间和表达量,或联合使用血小板衍生生长因子BB(plateletderivedgrowthfactorBB,PDGFBB)等“成熟”因子,有可能产生成熟的血管。导入不同基因到同一细胞以获得能同时表达“生长”和“成熟”因子的细胞,使细胞介导的基因转移在治疗性血管生成中具有独特价值。另一个可选择的策略是使用可调控多种血管生成因子表达的转录因子。

 
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