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表达     
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  expression
    Studies on the expression and mechanisms of p16~(INK4a)gene in human pancreatic adenocarcinoma
    P16~(INK4a)基因在人胰腺癌中的表达及其作用机制的研究
短句来源
    Effect of exogenous wild P53expression on sensitization to chemotherapeutic agents in human lungl cancer cells and cloning of related genes
    外源Wtp53表达对人肺癌细胞药物敏感性影响及相关基因克隆
短句来源
    Cloning of human brevican cDNA and the expression of its mRNA in human Glioma
    人短蛋白聚糖cDNA的克隆及其mRNA在人脑胶质瘤中表达的研究
短句来源
    Recombinant Expression of Interleukin-18 and Its Antitumor Effects
    IL-18的重组、表达及其抗肿瘤作用的研究
短句来源
    Expression of Human SolubleCD40 Ligand in Pichia pastoris and Study on Its Biological Functions
    人可溶性CD40配体在毕氏酵母中的高效表达及其生物学功能的研究
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  express
    A Study on the Express of Relative Oncogenes of Cell Cycle Modulator in Precancerous Lesions of Gastric Cancer and the Theraprutic Mechanism of Wei Yan Xiao
    胃癌癌前病变细胞周期调控因子的基因表达及胃炎消作用机制研究
短句来源
    Express of MCM5 in Colorectal Cancer and Diagnosis of Colorectal Cancer by Detection of Detection of MCM5 in Stool
    大肠癌MCM5的表达及粪便检测MCM5诊断大肠癌的初步研究
短句来源
    A STUDY ON RELATIONSHIP BETWEEN THE EXPRESS ON 72KD TYPE Ⅳ COLLAGENASE IN GASTRIC MUCINOUS CELL CARCINOMA AND CANCER INVASION
    胃粘液细胞癌中72KDⅣ型胶原酶的表达与其浸润的关系
短句来源
    A study of c-src Gene Express Product pp60 ̄(c-src)in Esophageal Carcinoma
    Src基因产物pp60~(c-src)在食管癌中表达的研究
短句来源
    LETHAL EFFECT OF 5 FC ON MAMMALIAN CELLS GENETICALLY MODIFIED TO EXPRESS CYTOSINE DEAMINASE
    5-FC对经基因修饰而表达胞嘧啶脱氨酶的哺乳类细胞杀伤作用
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  positive
    EXPRESSION OF C-MYC, HA-RAS AND KI-RAS ONCOPROTEINS IN PERIPHERAL BLOOD MONONUCLEAR CELLS FROM HBsAg POSITIVE PATIENTS WITH CHRONIC LIVER DISEASES
    C-myc、Ha-ras和Ki-ras癌蛋白在HBsAg阳性的慢性肝脏疾病患者外周血单个核细胞中的表达
短句来源
    Expression of chromogranin A positive cells in colon cancer
    嗜铬素A阳性细胞在结肠癌组织中的表达
短句来源
    Pulmonary adenosquamocarcinoma cell carcinoma with positive HLA一DR staining of adenocarcinoma cells
    腺癌细胞HLA—DR表达阳性的肺腺鳞癌
短句来源
    The Relationship Between the Positive Expression of p53 Gene Product in Gastric Cancer Tissue and Its Biological Significance
    胃癌组织中p53基因产物阳性表达与其生物学意义的关系初探
短句来源
    Positive Relationship of p53 and p21 Overexpression in Lymph Node Metastasis Propensity in Patients with Gastric Cancer
    P53和P21过表达与胃癌淋巴结转移呈正相关
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  gene expression
    Study on the Gene Expression of Vascular Endothelial Growth Factor (VEGF) & Its Receptors in Human Hepatocellular Carcinoma and the Inhibitory Effect of Antisense VEGF RNA on the Growth of Liver Cancer Cell in Vivo & in Vitro
    人肝细胞癌血管内皮生长因子及受体基因表达和其反义RNA体内外抑瘤作用的研究
短句来源
    Study on Gene Expression Spectrum and Reversal Strategy of Multidrug-resistant Leukemia Cells
    白血病细胞多药耐药基因表达谱变化及其逆转策略的研究
短句来源
    Study on the Diagnosis and Treatment of Gastric Stromal Tumor and Related Gene Expression
    胃间质瘤的诊治和相关基因表达的研究
短句来源
    Blockage and Transcriptional Gene Expression Profiles of HGF/SF-met Signaling Pathway in Colorectal Carcinoma
    大肠癌HGF/SF-met信号通路转录诱导基因表达谱及阻断作用研究
短句来源
    Study of Gene Expression Profile of Chronic Myeloid Leukemia
    慢性粒细胞白血病基因表达谱的实验研究
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  expression
Further, manzamine A (50 μM) substantially down regulated the expression of p53 while sarcophine (50 μM) slightly induced the level of p21.
      
Expression of OPN in rat kidney with different doses of vitamin K3 injection
      
In the present paper the expression of n-dimensional survival distribution functions of the processes {δt} and {γt}, and their Lebesgue decompositions are derived.
      
In this paper, by using the explicit expression of the kernel of the cubic spline inter-polation, the optimal error bounds for the cubic spline interpolation of lower soomth functions are obtained.
      
Further, an expression of the vertex partition function is also found.
      
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  express
We express them in terms of generatorsEij ofU(gl(n)) and as differential operators on the space of matrices These expressions are a direct generalization of the classical Capelli identities.
      
We express the vanishing conditions satisfied by the correlation functions of Drinfeld currents of quantum affine algebras, imposed by the quantum Serre relations.
      
Many studies, both experimental and numerical, were devoted to the electric current of corona discharge and some mathematical models were proposed to express it.
      
To improve the reconstruction quality, the DCT_M model is proposed to express the excitation spectral parameter, which transforms the variable length vector to fixed dimension vector through DCT transformation.
      
The digital elevation model (DEM), an important source of information, is usually used to express a topographic surface in three dimensions and to imitate essential natural geography.
      
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  positive
Tilting modules for classical groups and howe duality in positive characteristics
      
In this note we present a very simple method of proving that some hyperbolic manifoldsM have finite sheeted covers with positive first Betti number.
      
For the case of positive characteristic we use the classification of finite irreducible groups generated by pseudoreflections due to Kantor, Wagner, Zalesski? and Sere?kin.
      
Semistable principal bundles-II (positive characteristics)
      
Computing invariants of reductive groups in positive characteristic
      
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  gene expression
Zinc finger genes are some of the largest gene families in humans, and Zinc finger proteins play an essential role in altering gene expression by acting as transcription factors.
      
Alterations of gene expression profiles induced by sulfur dioxide in rat lungs
      
The present investigation aimed at analyzing the gene expression profiles of the lungs of Wistar rats short-term (20 ppm, 6 h/day, for seven days) and long-term (5 ppm, 1 h/day, for 30 days) exposed to SO2 by Affymetrix GeneChip (RAE230A) analysis.
      
mRNA extracted from LNC of lymphomas and reactive lymph node hyperplasia were respectively marked with biotin and hybridized with Gene Expression Chips, resulting in differentially expressed genes.
      
Using Gene Expression Chips, many differentially expressed genes were uncovered.
      
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  其他


The changes of tyrosine transaminase activity (TAT) and nucleotide 5'-phosphodiesterase activity (5'-NPDase) during foetal development and carcinogenesis in rats and in human beings were observed. Results so far obtained indicate that (1) a higher positive rate of the fastest moving isoenzyme band for 5'-NPDase has been noted in AFP (-) patients with liver cancer, and (2) TAT, 5'-NPDase and AFP may be taken together as good markers for the study of gene expression during liver caroinogenesis and foetal development....

The changes of tyrosine transaminase activity (TAT) and nucleotide 5'-phosphodiesterase activity (5'-NPDase) during foetal development and carcinogenesis in rats and in human beings were observed. Results so far obtained indicate that (1) a higher positive rate of the fastest moving isoenzyme band for 5'-NPDase has been noted in AFP (-) patients with liver cancer, and (2) TAT, 5'-NPDase and AFP may be taken together as good markers for the study of gene expression during liver caroinogenesis and foetal development.

本文测定了大鼠及人体胚胎发育和癌变过程中TAT和5′-NPDase活力变化,所得结果表明: (一)5′-NPDase快速同工酶区带在甲胎蛋白(AFP)阴性肝癌患者血清中阳性率较高。(二)TAT,5′-NPDase和AFP也许可作为研究癌、胚以及肝癌癌变过程中基因表达的三个互补生化指标。

The rat hepatomas have been in-duced by N-N-dimethyl-p-(m-tolyla-zo)-aniline and the morphologicalchanges of its liver have been observedat three chosen stages of carcinogene-sis.The amounts of chromatin com-ponents have been determined in paral-lel with the morphological observa-tions.There were no apparent chan-ges in histones as the cells grew ma-lignantly.But the contents of chroma-tin nonhistone proteins and the non-histone proteins/histones ratios increas-ed significently during the carcinoge-nic process.Furthermore...

The rat hepatomas have been in-duced by N-N-dimethyl-p-(m-tolyla-zo)-aniline and the morphologicalchanges of its liver have been observedat three chosen stages of carcinogene-sis.The amounts of chromatin com-ponents have been determined in paral-lel with the morphological observa-tions.There were no apparent chan-ges in histones as the cells grew ma-lignantly.But the contents of chroma-tin nonhistone proteins and the non-histone proteins/histones ratios increas-ed significently during the carcinoge-nic process.Furthermore the increaseof nonhistone proteins was detectedbefore the appearance of pathomor-phological changes.These results pos-sibly indicate that the changes of chro-matin nonhistone proteins are relatedto the malfunction of the gene expres-sion of rat liver cell and consequentlymake the cancer develop.

平行观察了三甲基奶油黄(3′-Me-DAB)诱发大鼠肝癌不同期的病理形态变化及染色质组分含量变化。染色质非组蛋白含量以及非组蛋白与组蛋白的比值,随细胞癌变而逐渐增加,而且这些变化出现在细胞形态变化之前。表明非组蛋白含量的增加和细胞基因表达失常、从而出现癌变有关。

It was found in the present study that the aldolase isozyme pat- tern in the liver of mouse bearing Ehrlich ascites tumor in both acetate membrane and polyacrylamide gel electrophoresis was different from that of the normal liver, but similar to that of the tumor cell. There was no significant difference in the chemical composition and template activity in a cell free system with E.coli RNA polymerase of chromatin isolated from the host liver and that from the normal liver,However,the chromatin from the tumor...

It was found in the present study that the aldolase isozyme pat- tern in the liver of mouse bearing Ehrlich ascites tumor in both acetate membrane and polyacrylamide gel electrophoresis was different from that of the normal liver, but similar to that of the tumor cell. There was no significant difference in the chemical composition and template activity in a cell free system with E.coli RNA polymerase of chromatin isolated from the host liver and that from the normal liver,However,the chromatin from the tumor cell had higher contents of non-histone proteins and RNA than that from the normal liver, while the contents of histone were similar in both chromatins. Furthermore, the template activity of chromatin from the tumor cell was higher than that from the normal liver. The possible correlation of these results with the alteration of gene expression of aldolase isozymes was discussed.

①醛缩酶同工酶谱:在醋酸薄膜电泳图上,艾氏腹水癌及其宿主肝均出现三条带,正常肝则只有两条带。在聚丙烯酰胺凝胶电泳图上,宿主肝与正常肝的差别同上;②染色质的组蛋白,非组蛋白、RNA含量及体外传录活性:宿主肝与正常肝之间均无明显差别。艾氏腹水癌除组蛋白不变外,其他均显著高于正常肝。对上述结果与醛缩酶基因表达改变的关系作了讨论。

 
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