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      抗肿瘤化合物     
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  antitumor compound
     Determination the plasma concentration of SYUIQ-5,a novel antitumor compound,by HPLC in rat
     HPLC法测定大鼠血浆中抗肿瘤化合物SYUIQ-5的浓度
短句来源
     It was shown that emodin can inhibit the growth of tumor strain such as Hela and K562. The aloe-emodin is a new selective antitumor compound, which shows inhibition against neuroectoderm tumor of immune deficient mouse without affecting to the animals or the growth of the normal fibroblast cell.
     研究显示:大黄素能抑制Hela、K562等瘤株的生长; 芦荟大黄素是一种新型的具有选择性的抗肿瘤化合物,它对免疫缺陷小鼠的神经外胚层肿瘤有抑制作用,但是对动物本身没有影响,也不影响正常的成纤维细胞生长。
短句来源
  antitumor compounds
     Screening of Antitumor Compounds from Natural Compounds or Its Derivatives by Using the Recombinant Human DNA Topoisomerase Ⅰ as Target
     以重组人DNA拓扑异构酶Ⅰ为靶位从天然产物及其衍生物中筛选抗肿瘤化合物
短句来源
     In order to rapidly screen new antitumor compounds targeting at human DNA topoisomerase Ⅰ (hTopoⅠ), hTopoⅠ was first expressed by \$P.
     为了在体外以人DNA拓扑异构酶Ⅰ(hTopoⅠ)为靶位进行抗肿瘤化合物的快速筛选,首次使用毕赤酵母表达了hTopoⅠ。
短句来源
     AIM: In order to find new type of antitumor compounds and study the contribution of hydroxyl groups on the sugar part to the antitumor activity of 8 Cl adenosine, the retinoid analogs of adenosine and the derivatives of 8 Cl adenosine were synthesized.
     目的:为寻找新型抗肿瘤化合物和探讨糖环羟基对8Cl腺苷的抗肿瘤活性的影响,合成了腺苷的维甲类似物和8Cl腺苷衍生物。
短句来源
     Aim To design and synthesize new methoxyl carbazole analogues as antitumor compounds.
     目的 设计合成新型甲氧基咔唑类抗肿瘤化合物
短句来源
  anti-tumor compounds
     Study on Molecular Biology Mechanism of Anti-tumor Compounds
     抗肿瘤化合物的分子生物学机制研究
短句来源
  anti cancer compound
     RP HPLC determination of pharmacokinetics of 8 Cl A an anticancer compound in dog body
     HPLC测定犬血中抗肿瘤化合物8-氯腺苷的药代动力学
短句来源
     PHARMACOKINETICS OF 8-CHLORO ARDENOSINE, A NEW ANTICANCER COMPOUND IN RATS
     新抗肿瘤化合物8-氯腺苷在大鼠体内的药代动力学研究
短句来源
     These results suggest that PIC BE is an effective anti cancer compound, and K 562 /ADM cell line with MDR has no resistance to it.
     以上结果提示 ,PIC- BE是一种有效的抗肿瘤化合物 ,且已产生 MDR的 K5 6 2 / ADM细胞对它不具耐药性。
短句来源
     There fore,EBB can be considered as a potent anticancer compound.
     提示EBB是一种有前途的抗肿瘤化合物
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      antitumor compound
    On the other hand, very low levels of HMPMM, generally considered to be a potentially active antitumor compound, were detected in the target tissues, whereas this hydroxylated metabolite was stable and easily determined in plasma.
    例句来源      
    In vivo activity on murine tumors of a novel antitumor compound, N-β-dimethylaminoethyl 9-carboxy-5-hydroxy-10-methoxybenzo[a]ph
    例句来源      
    A novel antitumor compound, N-β-dimethylaminoethyl 9-carboxy-5-hydroxy-10-methoxybenzo[a]-phenazine-6-carboxamide sodium salt (NC-190) was evaluated for its antitumor activity in experimental murine tumor systems.
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    Toremifene, a new antiestrogenic antitumor compound, has several biologically active metabolites.
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    Mechanism of tumor cell killing by HO-221, a novel antitumor compound
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      antitumor compounds
    Our research will be helpful to clarifying the biosynthesis mechanism of such kind of antibiotic and to producing new antitumor compounds.
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    Given the novel mechanisms of action of new antitumor compounds coupled with their favorable toxicity profiles, however, continued improvements in survival and quality of life may be achieved in patients with advanced disease.
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    These antitumor compounds possess two trisaccharide chains attached at C-7 and C-10, each of them with structural variability, mainly at the distal deoxysugar moieties.
    例句来源      
    The aureolic acid family of antitumor compounds: structure, mode of action, biosynthesis, and novel derivatives
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    We examined several biochemical parameters that may contribute to the differential sensitivity of the cell lines used in our laboratory to the toxic effects of antitumor compounds.
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      anti-tumor compounds
    Porosified Silicon Wafer Structures Impregnated With Platinum Anti-Tumor Compounds: Fabrication, Characterization, and Diffusion
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    The lessons learned should be applied in the development of next generation indoline anti-angiogenic and anti-tumor compounds.
    例句来源      
      anti cancer compound
    More recently, research has suggested that it may also contain an anti-cancer compound.
    例句来源      
    There is no hard data known to us that demonstrates that Gm-Csf increases the toxicity of any anti-cancer compound.
    例句来源      



             1-acety-3-O-toluyl-5-fluorouracil orally administered to mice bearing tumor (S_(180), and U_(14) tumors) showed greater antitumor activitesthan did FT-207. A-OT-FU showed the very remarkable antitumor properties,being effective against Hep (H_(22)) cancer. A-OT-FU was found to be a veryefficaious (especially in Hep cancer), broad-spectrum compound. It might beconsidered to be a new generation of antitumor subject.
                选用肉瘤180(S_(180))、子宫颈癌14(U_(14))和肝癌(Hep;H_(22))三种瘤株试验1-乙酰基-3-邻-甲基苯甲酰基-5-氟尿嘧啶的抗肿瘤活性,结果表明这是一种高效、广谱的抗肿瘤化合物,尤其对肝癌有较高的抑瘤率。
    文摘来源
             Agarose gel electrophoresis and spectroscopy were used to investigate the interaction of AD 89 with DNA. The effect of drug on intact cell DNA was evaluated by using alkaline elution technique.The results showed that AD 89 decreased the mobility of supercoiled PUC9 DNA significantly.The interaction of calf thymus DNA with AD 89 led to the red shift of the peaks of absorption,and the greater the ratio of DNA/AD 89 was the greater the red shift would be.These results are similar to those of mito xantro...
                采用琼脂糖电泳、紫外光谱法及碱性洗脱法研究新蒽环类抗肿瘤化合物AD-89对细胞内外DNA的作用,以了解其抗肿瘤作用机理。结果发现:AD-89能明显抑制肿瘤细胞生长,减慢超螺旋的PUC9DNA的电泳迁移率;小牛胸腺DNA与AD-89作用后可使AD-89的紫外吸收峰出现明显红移,提示AD-89能嵌入DNA;AD-89在大剂量时能引起DNA单链断裂,但不引起蛋白相关的DNA单链断裂,而在5μmol/L和10μmol/L浓度时均可引起明显的DNA链间交叉联接,同时还可引起少量DNA-蛋白交联。由此表明,AD-89可能是一个主要通过引起细胞内DNA链间交联而发挥抗肿瘤作用的嵌入剂。
    文摘来源
             Abstract Three kinds of newly synthesized antitumor compounds (spirobromine, C 16 H 36 Br 2N 4·2HCl and C 17 H 38 Br 2N 4·2HCl) have been studied by normal and surface enhanced Raman spectroscopy. The assignments of the Raman modes have benn given. The Raman bands at 2834,2856,2903,2957,2977 cm -1 are characteristic of CH 2 stretching vibrations. The strong band at 1656 cm -1 is assigned to γ(C=0). Bands at 848,1292 and 1456 cm -1 are attributed to the C H stretching mo...
                几种哌嗪类抗肿瘤化合物的拉曼光谱刘社文1梁二军1李祥杰2(1郑州大学河南省激光应用技术重点实验室,2郑州大学化学化工学院,郑州450052)RamanSpectraofSeveralAntitumorPiperazinesCompoundsLiuSh...
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