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抗肿瘤疫苗
anti-cancer vaccine
Objective: To construct recombinant bacteriophage T7 anti-cancer vaccine targeting epidermical growth factor receptor. 目的:构建表皮生长因子受体(EGFR)为靶向的重组T7噬菌体抗肿瘤疫苗。 短句来源 Thesubclone DNA fragments with different function and better presentation of mimic antigen were inserted into thebacteriophage T7 expression vector. The anti-cancer vaccine of recombinant bacteriophages T7 were constructedand the mice were immunized. The specific antibodies and the cytotoxic T lymphocyte response were detected withdot blot and MTT method, respectively. 将膜外序列不同功能及模拟抗原呈递较佳的亚克隆DNA片段插入T7噬菌体表达载体,从而构建了重组T7噬菌体抗肿瘤疫苗并用于动物免疫注射,用斑点印迹(dotblot)和MTT法分别检测到特异性抗体和细胞毒性T淋巴细胞反应。 短句来源 anti-tumor vaccine
The results suggest, as a new concept anti-tumor vaccine, DC pulsed by TAA may play an important role in therapy and prevent against tumor. 提示经肿瘤抗原激活的DC作为一新概念上的抗肿瘤疫苗有可能在肝癌的预防及治疗中发挥重要作用. 短句来源 Conclusion: As a newconcept anti - tumor vaccine of DC pulsed by TAA may play an important role in therapy of tumor. 结论：经肿瘤抗原激活的DC作为一新概念上的抗肿瘤疫苗有可能在肿瘤的治疗中发挥重要作用。 短句来源 Conclusion: The fusion cells had typical morphologies and are safe as a anti-tumor vaccine in vivo and vitro. 结论:融合细胞具有作为抗肿瘤疫苗应具备的低增殖能力和不成瘤的安全性; 融合疫苗可明显促进T淋巴细胞的增殖能力说明将其作为抗结直肠癌特异性免疫治疗方法有进一步研究的意义。 短句来源 “抗肿瘤疫苗”译为未确定词的双语例句
Immunity Effects Mechanism Treated with Elemene- Combo Tumor Vaccine 榄香烯复合抗肿瘤疫苗免疫的效应机制 短句来源 Advances in the study of antitumor vaccines with tumor-associated carbohydrate antigen 基于肿瘤相关糖抗原的抗肿瘤疫苗研究进展 短句来源 Conclusion DC pulsed by TAA may play an important role for tumor therapy 结论 经肿瘤抗原激活的DC作为一新概念上的抗肿瘤疫苗有可能在治疗肿瘤及预防其术后复发和转移中发挥重要作用。 短句来源 Progress on Dendritic Cell Vaccines in Tumor Immunotherapy 树突状细胞抗肿瘤疫苗研究进展 短句来源 Developing more effective anticancer vaccine has been one of the major goals of cancer immunotherapy. 目前开发新型的有效的抗肿瘤疫苗已成为肿瘤免疫治疗的主要目标。 短句来源 更多 
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These results suggest that CAGE would be a valuable target for the development of an anti-cancer vaccine.
例句来源 
[Purpose]To explore if the immune response induced by dendritic cells (DS) plus tumor extract in vitro can protect the node mice a－gainst trabnsplanting of tumor and inhibit the growth of tumor cells in these mice [Method] DC well isolated and purified from the patients with hepatocel－lualar caancer (HCC)abnd incubated with combination of granulocyle/macrophage colony stinulating factor, lnterleukin 4, and the crude tumor－associat－ed antigen extracted from human hepatocellular cancer cell line HepG2 cells ... [目的]讨究树突状细胞（DC）体外诱导的抗肝癌细胞免疫能否预防裸鼠人肝癌移植癌发生及抑制课鼠人肝癌移植瘤生长。[方法]联合应用粒／巨噬细胞集落刺激因子（GM－CSF）及白介素－4（IL－4）直接从肝癌患者外周血中培养DC：以人肝癌细胞系HepG2肿瘤细胞的肿瘤抗原粗提物刺激DC；DC激活同源的T淋巴细胞产生细胞毒性T淋巴细胞（CYL）；以DC激活的CIL预防性接种于探鼠皮下观察其后接种的人肝癌细胞系HepG2移植瘤发生率；并观察该CTL对已接种裸鼠的人肝癌细胞系HepG2移植瘤生长的影响。[结果]DC诱导的工体外对HepG2肿瘤细胞具有高效而特异杀伤作用，在裸鼠体内不能预防探鼠人肝癌细胞系HepG2移植瘤发生，而且能抑制该移植瘤生长。[结论]经肝癌肿瘤相关抗原激活的肝癌患者外用血DC体外诱导的抗肿瘤细胞免疫在体内外均具有良好的抗肿瘤作用。提示DC作为一新概念上的抗肿瘤疫苗有可能在人肝癌的预防及治疗中发挥重要作用。 文摘来源 To study if the immune response in vivo induced by dendritic cells (DC) pulsed with tumor extract can inhibit the growth of implanted tumor and reject the challenge of tumor cells in nudes, we isolated and purified DC from hepato-cellcular cancer(HCC) patient with combination of granulocyte /macrophage colony stimulating factor and interleukin 4; extracted tumor-associated antigen from human hepatocellcular cancer cell line HepG2 tumor cells; initiated the T lymphocyte with DC pulsed by the TAA to product c... 为研究树突状细胞(DC)体外诱导抗肿瘤免疫能否预防裸鼠移植瘤发生及抑制裸鼠移植瘤生长,联合应用粒/巨噬细胞集落刺激因子(GM-CSF)及白介素4(IL-4)直接从肝癌患者外周血中培养出DC;以源于人肝癌细胞系HepG2的肿瘤抗原粗提物刺激DC,DC激活同源的T淋巴细胞;以被激活的T淋巴细胞预防性接种于裸鼠皮下,观察进一步接种的人肝癌细胞系HepG2移植瘤发生;观察被激活的T淋巴细胞抑制已接种于裸鼠的人肝癌细胞系HepG2移植瘤生长.发现,DC诱导的抗肿瘤免疫不仅能预防裸鼠人肝癌细胞系HepG2移植瘤发生,而且能抑制该移植瘤生长.提示经肿瘤抗原激活的DC作为一新概念上的抗肿瘤疫苗有可能在肝癌的预防及治疗中发挥重要作用. 文摘来源 Objective: To study the mechanism of antitumor immune response induced by dendriticcells (DC) in the inhibition of growth of implanted tumor in nude mice by way of inducing tumor cell apop-tosis. Methods: Isolated and purified DC derived from hepatocellular cancer (HCC) patients with granulo-cyte/macrophage colony stimulating factor and interieukin 4, extracted tumor - associated antigen(TAA) from human hepatocellular cancer cell line HepG2 tumor cells, Stimulated T lymphocytes with DCpulsed by TAA to produ... 研究树突状细胞（ＤＣ）体外诱导的细胞免疫抑制裸鼠移植瘤生长作用及其机理。方法：联合应用粒／巨噬细胞集落刺激因子ＫＭ－ＣＳＦ）及白介素－４（ＩＬ－４）直接从肝癌患者外周血中培养出ＤＣ，以人肝癌细胞系ＨｅｐＧ２肿瘤细胞的肿瘤抗原粗提物刺激ＤＣ，ＤＣ激活同源的Ｔ淋巴细胞，建立裸鼠人肝癌细胞系ＨｅｐＧ２移植瘤模型，以被激活的Ｔ淋巴细胞治疗裸鼠ＨｅｐＧ２移植瘤并观察治疗效果，检测移植瘤标本肿瘤细胞凋亡情况。结果：ＤＣ诱导的Ｔ细胞免疫能够诱导裸鼠人肝癌细胞系ＨｅｐＧ２移植瘤肿瘤细胞大量凋亡从而抑制裸鼠ＨｅｐＧ２移植瘤生长。结论：经肿瘤抗原激活的ＤＣ作为一新概念上的抗肿瘤疫苗有可能在肿瘤的治疗中发挥重要作用。 文摘来源 << 更多相关文摘 
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