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   溶栓效果 的翻译结果: 查询用时:0.986秒
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溶栓效果     
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  thrombolytic effect
     Conclusion: All the regimens of UK 2 h, UK12 h and rt-PA have a significant thrombolytic effect, and UK2 h and rt-PA regimens are safer than UK12 h regimen.
     结论:UK2h、UK12h方案及rt-PA溶栓效果均好,但UK2h、rt鄄PA方案更安全。
短句来源
     The group of 7.5×104 U/kg UK temperature-sensitive liposome and the group of 15×104 U/kg UK were similar in thrombolytic effect,but the UK dose of the former was 1/2 of the latter and there was no hemorrhage in the former.
     7.5万U/kg UK热敏脂质体组与15万U/kg UK组比较溶栓效果相似,但前者UK用量仅为后者的1/2,且各脏器均未见出血。
短句来源
     Tenecteplase based on the alteplase is the third generation thrombolytic agent,Th~(103)、Asn~(117) and Lys~(296)-His-Arg-Arg~(299) in alteplase molecule are replaced by Asn、Glu and Ala-Ala-Ala-Ala in tenecteplase. Tenecteplase has longer half life,better thrombolytic effect,shorter thrombolytic time,better fibrin-specific recognition,convenient use and lower danger,etc.
     替奈替普酶(Tenecteplase)是在阿替普酶(Alteplase)的基础上,用Asn、Glu和Ala-Ala-Ala-Ala代替其分子中的Th103、Asn117和Lys296-His-Arg-Arg2993个位点而得到的生物技术制品,属于新型的第3代溶栓药,具有体内半衰期长,溶栓效果好,溶栓时间短,纤维蛋白特异识别性强,使用方便及危险性低等特点。
短句来源
     Objective: To investigate the thrombolytic effect of a new a type of plasminogen activator, human tissue urokinase type plasminogen activator(HTU-PA) which is constructed with both scuPA and tPA, in patients with acute myocardial infarction(AMI).
     目的:观察一种新的含有tPA和scuPA的纤溶酶原激活剂-人组织型纤溶酶原激活剂(HTU-PA)对急性心肌梗死的溶栓效果
短句来源
     GMP- 140 of platelet surface is associated with thrombosis and thrombolysis, it may be an important index to assess thrombolytic effect.
     血小板表面GMP-140与血栓形成及溶解有关,是判定溶栓效果的一项重要指标。
短句来源
更多       
  thrombolytic efficacy
     Thrombolytic Efficacy of rt-PA in Embolic Stroke of Rabbits by ~(99)Tc~m Trace
     ~(99)Tc~m示踪观察rt-PA对家兔脑卒中模型的溶栓效果
短句来源
     mortality and complicating bleeding:group Athrombolytic efficacy of tPA iss superior to UK.
     病死率、出血并发症的发生率:A组<B组<C组,P均<0.01。 结论:PIEAT治疗急性脑梗塞疗效优于周围静脉给药,tPA的颈内动脉溶栓效果优于UK。
短句来源
     [Method] The simple vitro-thrombolysis-equipment was used to study the targeting thrombolytic efficacy of UKTsL in vitro.
     方法在简易体外溶栓装置上研究了UKTsL的体外靶向溶栓效果;
短句来源
     Compared to UK liposomes of the same dose, the targeted UK liposomes showed significantly improved thrombolytic efficacy ( P <0 01 in wet weights decrease and P <0 05 in dry weights decrease respectively).
     与同剂量的普通脂质体相比 ,血栓靶向尿激酶脂质体溶栓效果显著改善 (湿重时P <0 0 1,干重时P <0 0 5 ) ,表现出明显的靶向溶栓能力。
短句来源
     [Objective] To investigate the in vivo and in vitro thrombolytic efficacy of urokinase encapsulated thermosensitive liposome (UKTsL).
     目的研究尿激酶热敏脂质体(UKTsL)的体内外溶栓效果
短句来源
更多       
  thrombolysis effect
     Conclusion The pulse ultrasound of 2 MHz and 1.8 W/cm2 has a direct thrombolysis effect in vitro and the thrombolysis rate is negatively correlated with the clotting time and positively correlated with the insonation time.
     结论在体外实验条件下,2MHz、1.8W/cm2的脉冲超声波有明确的直接溶栓效果,其溶栓率与凝龄成反比,与辐照时间成正比。
短句来源
     Analysis on the Thrombolysis Effect of Snake Venom Antithrombus Enzyme Used through Veinson Acute Myoeardial Infarction in 70 Cases
     对70例急性心肌梗塞行清栓酶静脉给药的溶栓效果分析
短句来源
     Thrombolysis Effect of New Thrombolytic Agent-Staphylokinase on Experimental Cerebral Microthrombi
     新型溶栓药—葡激酶对实验性脑微血栓溶栓效果的观察
短句来源
     Results: The four medication groups have significant thrombolysis effect in comparison with the NS group;
     结果 :四个用药组均比生理盐水对照组有显著溶栓效果 ;
短句来源
     Objective To discuss the thrombolysis effect, drug using window, and safety for cerebral infarction.
     目的 探讨降纤酶对脑梗死的溶栓效果、用药时间窗及安全性。
短句来源
更多       
  thrombolytic effects
     Objective: To report the thrombolytic effects of intravenous urokinase (UK) plus prostaglandin E 1 (PGE 1) on deep venous thrombosis (DVT).
     目的:观察静脉内联用尿激酶(UK)和前列腺素E1(PGE1)对下肢深静脉血栓(DVT)患者的溶栓效果
短句来源
     Methods The clinical data of 121 cases of AMI treated with intravenous thrombolytic therapy were analyzed retrospectively. The thrombolytic effects and the indication-related conditions and the thrombolytic profit were compared between the females and the males.
     方法依据121例AMI静脉溶栓治疗病人的临床资料作回顾性分析,比较男性、女性的溶栓效果、溶栓适应证相关条件及溶栓获益。
短句来源
     Thereby, SPECT 99mTc-MIBI was a good method forevaluation of the infarct size and thrombolytic effects.
     99mTc-MIBI心肌灌注断层显像是判断心梗范围、评价溶栓效果的较好手段。
短句来源
     Objective To observe the thrombolytic effects of recombinant urokinase-type plasminogen activator(ru-PA)compared with recombinant tissue-type plasminogen activator(rt-PA)on experimental pulmonary embolism in rats.
     目的观察在不同时间窗重组尿激酶型纤溶酶原激活物(ru-PA)的溶栓效果,并与重组组织型纤溶酶原激活物(rt-PA)的溶栓效果比较。
短句来源
     Objective To compare the thrombolytic effects of the two dosing regimes with urokinase(UK) in a canine model of pulmonary thromboembolism induced by radioactive blood clots.
     目的 比较治疗肺血栓栓塞症 (PTE)时尿激酶 (UK) 2h和 12h溶栓方案的溶栓效果及特点。
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      thrombolytic effect
    The simultaneous combination of 15 nM staphylokinase and 15 nM scu-PA resulted in maximal 3.8-fold increase in the thrombolytic effect as compared to the expected total effect of the individual agents.
          
    Terrilytin was revealed to exibit the thrombolytic effect and expressive affinity to the fibrin in comparison with other substrates of high and low molecular weight.
          
    The thrombolytic effect was also observed by exposing animals with existing arterial thrombosis to carbon monoxide (CO) (250?ppm, 2?h), a byproduct derived from heme degradation by HO-1.
          
    Macromolecular Ensembles of External and Internal Fibrinolysis: Ways to Enhance the Thrombolytic Effect (A Review)
          
    The thrombolytic effect of aspirin in animal model
          
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      thrombolytic efficacy
    The thrombolytic efficacy clearly depended on the thrombus age and the dose of urokinase applied.
          
    Efforts to improve the thrombolytic efficacy and pharma cological properties of plasminogen activators have taken several directions.
          
    For this pilot study, 25 patients were chosen as the sample size in order to get the first estimation of thrombolytic efficacy and safety.
          
    Further in vitro and in vivo studies are needed to evaluate the fibrin specificity, thrombolytic efficacy and system half-life of AnxB1ScuPA.
          
    Streptokinase and rt-PA must be adminis tered by intravenous infusion to ensure thrombolytic efficacy.
          
      thrombolytic effects
    Thrombolytic effects of intracoronary streptokinase on canine coronary artery thrombosis
          
    The thrombolytic effects after intravenous bolus injection of 200 kU/kg BM 06.021 were investigated in a canine model of coronary artery thrombosis.
          
    At equimolar dose, both improved antithrombotic and thrombolytic effects of SFH were observed in kappa-carrageenin inducing mouse-tail thrombosis model and rat inferior vena cava thrombosis model, respectively.
          
    They found the thrombolytic effects of tPA to be superior to those of urokinase in these animal models.
          


    In this article, the clinical data of 129 cases of thromboembolistic diseases of extremities are presented. Those were treated with snake venom antithrombotic enzyme(SVATE). The results showed that the total effective rate was 94.5%. Among these cases, the effective rate was 92% in 83 casse of thromboangiitis obliterans and 97.5% in 46 cases of thrombophlebitis or phiebothrombosis. Experimental study revealed that SVATE exhibited a multifunctional agent, including thromboclasis, anticoagulation and antithrombosis....

    In this article, the clinical data of 129 cases of thromboembolistic diseases of extremities are presented. Those were treated with snake venom antithrombotic enzyme(SVATE). The results showed that the total effective rate was 94.5%. Among these cases, the effective rate was 92% in 83 casse of thromboangiitis obliterans and 97.5% in 46 cases of thrombophlebitis or phiebothrombosis. Experimental study revealed that SVATE exhibited a multifunctional agent, including thromboclasis, anticoagulation and antithrombosis. It was suitable for the treatment of thromboembolistic diseases of extremities at various periods and effective too for the patients in the advanced stage. Through the contrast by the angiography before and after the treatment, it showed that the segmental full and defect dismissed. Contrast media appeared fully and passed easily. it proves that SVATE has stronger effect of thromboclasis.

    本文报道应用蛇毒抗栓酶(Svate)治疗四肢血管血栓栓塞性疾病129例,总有效率94.5%。其中血栓闭塞性脉管炎83例;血栓性静脉炎与静脉血栓形成46例。Svate系江浙产蝮蛇毒中提取的一种酶制剂,主要成份是精氨酸脂酶,具有溶栓、抗凝、抗栓等多种功能。适用于各种类型四肢血管血栓栓塞性疾病的不同病期,对晚期患者疗效亦佳。其溶栓效果已为治疗前后血管造影所证实。临床表现的促进组织新生、血管内膜的修复作用等,提示Svate中可能含有生长因子。

    The thrombolytic effect was compared between urokinase (UK) and human tissue plasminogen activator (t-PA) in rabbits with experimental iliofemoral artery thrombus. The results proved that the effectiveness of clot lysis was significantly higher with t-PA than with UK (37.5% versus 75% P<0.01). Decrease of fibrinogen in circulating blood induced by t-PA was less than that induced by UK, due to specific clot thrombolysis of t-PA. Therefore, t-PA is considered as a more effective and safer thrombolytic agent.

    本文用尿激酶(UK)和人体组织型纤溶酶原激活剂(t-PA)进行了兔髂股动脉血栓实验性溶解的对照研究。结果表明,t-PA的溶栓效果远较UK显著(37.5%对75%)(P<0.01),由于t-PA对血栓中的纤维蛋白原有一定的选择性作用,引起循环血液中的纤维蛋白原的下降不如UK明显。故t-PA是一种效果较好、治疗剂量时较为安全的溶栓剂。

    13 cases of reperfusion arrhythmias were observed in 15 patients with AMI treated by thrombolytic therapy. The incidence of reperfusion arrhythmias was 86.7%. It occured on 10~30 minutes after thrombolytic therapy (mean 21.8 minutes). Most of them were ventricular premature beats and ventricular tachycardias. The incidence of reperfuston arrhythmias was 50% (2/4) in 4 patients with LVEF>60% and 100% (9/9), in 9 patients with LVEF<60% (P<0.005). It seemed that lower LVEF had higher incidence of reperfusion arrythmias....

    13 cases of reperfusion arrhythmias were observed in 15 patients with AMI treated by thrombolytic therapy. The incidence of reperfusion arrhythmias was 86.7%. It occured on 10~30 minutes after thrombolytic therapy (mean 21.8 minutes). Most of them were ventricular premature beats and ventricular tachycardias. The incidence of reperfuston arrhythmias was 50% (2/4) in 4 patients with LVEF>60% and 100% (9/9), in 9 patients with LVEF<60% (P<0.005). It seemed that lower LVEF had higher incidence of reperfusion arrythmias. The incidence of reperfusion arrythmlas was interrelated with the effect of thrombolytie therapy. All the patients with obvious effect developed reperfusion arrhythmias.

    本文对15例AMI患者行溶血栓治疗,13例出现再灌注性心律失常,发生率为86.7%,均发生在溶栓疗法后10~30(平均21.8)分钟。多为室性早搏及室性心动过速。临床资料还表明,左室射血分数越低,再灌注性心律失常发生的机会越多;再灌注性心律失常的发生与溶栓效果有关。溶栓效果显著者均发生再灌注性心律失常,提示其发生可作为冠脉再通的指标之一。

     
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