Objective To establish the three-plasmid packaging cell line of the recombinant lentiviral vector encoding rat FasL gene for eukaryotic expression to meet the requisition for deep study on the effect of FasL transgene on inducing immune tolerance and protecting allografts in organic transplantation.
Objective To investigate the expression of heme oxygenase-1 and heat shock protein (HSP) 70 in renal allograft of acute rejection in rats, to provide a theoretical base in the diagnosis and treatment of acute renal rejection, to help us explore new immunodepressives and induce immune tolerance.
Induction of Immune Response by Synthetic Fragments of the Bovine Prion Protein and Their Analogues in Mice of Various Lines
The induction of immune and neural responses in acute neurological disease are important mechanisms of consequent new organ failures.
Induction of immune tolerance with heart-thymus composite allotransplantation in rats
Significant progress has been made in our understanding of the basic mechanisms underlying the induction of immune responses, which has led to a proliferation of rationally designed immunotherapeutic strategies.
One aim of the genetic modification of tumor cells is the generation of immunogenic variants that can be used for the induction of immune responses against tumors.
LAMPs can modulate the immune system, and could induce immune cells apoptosis or death.
The human gut offers more than 200 m2 of mucosal surface, where direct interactions between the immune system and foreign antigens take place to eliminate pathogens or induce immune tolerance toward food antigens or normal gut flora.
Indeed, recent findings suggest that targeting antigen-specific T cells can reinstate regulatory mechanisms and thus induce immune tolerization.
The mechanisms through which chemicals induce immune responses resulting in allergic sensitization, the factors that govern the characteristics of those responses, and the form allergic reactions will take are only partially understood.
We have shown that peptide mimotopes of carbohydrates induce immune responses to carbohydrate structures with in vivo and vitro functionality.