Objective The expression of IFN-γ,IL-2,IL-12 in patients with tuberculous and malignant pleural effusion were analyzed,so as to find out the role of Th1 immune response of helper T cell hypotype in the pathophysiological process of tuberculous and malignant pleural effusion.
Objective To study dynamic changes of expression of interleukin-1 β (IL-1 β) in the intracerebral hemorrhage (ICH) fuci and to investigate the pathophysiological process after ICH so as to provide theory basis for clinical treatment.
The IL-6 level was no correlated with the TGF-β1. Conclusions IL-6 and TGF-β1 takes important role in the pathophysiology of cerebral hemorrhage .
Objective To detect antibodies to peripheral nerve myelin protein 22(PMP22),interleukin-6(IL-6) and tumour necrosis factor α(TNF-α) concentrations in the serum in Charcot-Marie-Tooth(CMT) patients for observing whether immune mechanisms was participating in the pathophysiology in CMT.
Conclusions Upregulation of CD54 in neutrophils,lymphocytes and monocytres in the patients with COPD during the acute attack stage,and upregulation of CD62L and CD44 in lymphocytes in the patients with COPD during the stable stage may participate in the pathophysiologic processes of COPD.
Material and Methods To study associated pathologic and pathophysiologic changes of myocardial hypertrophy, the male Wistar rats of myocardial hypertrophy induced by coarctation of abdominal aorta (CAA) were randomized into 4 groups of 12 each: 2-week group (CAA2W group), 4-week group (CAA4W group), 8-week group (CAA8W group), and 16-week group (CAA16W group).
(2) to build experimental model of orthotopic liver transplantation in rat (ROLT), summarize operative skills and technique, observe the development process and basic pathophysiologic changes of acute rejection (AR) following allotransplantation from Lewis (LEW) to Brown Norway (BN) rat;
(2)建立大鼠原位肝移植动物模型,总结手术技巧和方法,观察 Lewis(Lew)到 Brown Norway(BN)大鼠同种异体急性排斥反应(acute rejection, AR)的发生发展以及基本病理生理指标变化过程。
After referenced relevant documents on the etiology of β-cells injuring of T2DM in recent 10 years,the author summarized the concrete researching prospect of pathology and physiology on β-cells injuring of T2DM from defect of the function that β-cells in islets of Langerhans secrete insulin and βcells death.
It is suggested that among the immunogolbulin class-specific immune complexes activating complement,there exists different sigificance in pathology and physiology in which IgG and IgA /C3 -CICmay be involved in the process of liver injury .
Very diverse pathophysiological exposures (stimuli, stresses), such as heat, ionizing radiation, pathogens, cytokines cause both forms of cell death in the same cell population.
It is suggested that under pathophysiological conditions, the necrotic cell destruction should amplify and catalyze pathological processes.
It is obvious that the depot of osmotically inactive sodium should be taken into account in studies of cardiovascular system function and in pathophysiological approaches to edematous syndrome and hypertension.
The most probable pathophysiological mechanisms of adverse effects of continuous hypokinesia (maladaptation) on functional systems of the human body are described.
The important physiological, pharmacotherapeutical and pathophysiological significance of this new fact is discussed.