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免疫干预治疗
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  immune intervention therapy
     Application of glucosidorum tripterygii tororum as an immune intervention therapy in patients with type 1 diabetes mellitus
     雷公藤多甙用于1型糖尿病患者的免疫干预治疗
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  “免疫干预治疗”译为未确定词的双语例句
     Conclusion gp96 polypeptide complex-dendritic cell vaccine could induce Th0 differentiate to Th1, indicating its capability against tumuor.
     结论gp96多肽复合物DC疫苗可诱导Th1/Th2平衡向Th1漂移,显示了gp96多肽复合物DC疫苗可显著提高机体的免疫能力,为临床免疫干预治疗奠定基础。
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     Conclusion:Highly mixed DC/Th0 ration induced Th0 differentiation to Th1, low mixed DC/Th0 ration induced Th0 differentiation to Th2, DC regulating immunology response type were plastic which provided the basis for clinic GVHD therapy.
     低比例混合时 ,诱导Th0向Th2分化。 显示人外周血DC在调控T淋巴细胞免疫应答类型上具有可塑性 ,为临床移植物抗宿主病 (GVHD)免疫干预治疗奠定基础。
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     Immune-intervention therapy will be a potential method to treat HPV infection in the future.
     免疫干预治疗将成为HPV治疗的重要手段,DNA疫苗为治疗各种HPV相关感染和肿瘤提供了有力武器,E6、E7蛋白是HPV16治疗性疫苗重要靶抗原。
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     Conclusions A clone of murine GAD65 is successfully constructed. It is a basis step for further construction of expression plasmid that expresses GAD65 and for immunologic intervention of T1DM.
     结论成功的克隆了小鼠GAD65基因,为构建GAD65基因疫苗以及糖尿病的免疫干预治疗打下基础。
短句来源
     The results suggest the onset of IDDM may relate to autoimmune,and it is important to conduct the treatment of IDDM with immunosurpress as soon as possible.
     结果提示IDDM发病早期存在自身免疫失调,对IDDM免疫干预治疗应在发病早期进行。
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  相似匹配句对
     Immune-based Therapeutic Intervention and Treating AIDS with TCM
     免疫干预疗法与中医药治疗艾滋病
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     Intervention therapy of MDS
     骨髓增生异常综合征的干预治疗
短句来源
     The Therapeutics of Myocardial Fibrosis
     心脏纤维化的干预治疗
短句来源
     4) immunogene therapy;
     (4)免疫基因治疗
短句来源
     (3) Immunogene therapy;
     (3)免疫基因治疗;
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Unfixed cryostat sections of pancreas from blood group O human were used as the test substrate,the cytopklasmic islet cell antibody(ICA) in 82 cases of patients with IDDM was measuerd by standard indirect immunofluorescence technique. At same time,the peripheral blood T lymphoglocyte subsets in 35 cases of patients with IDDM were determined by means of series monoclonal antibodies. The results showed that the newly diagnosed IDDM patients were found to have higher incidence of positive serum ICA than patients...

Unfixed cryostat sections of pancreas from blood group O human were used as the test substrate,the cytopklasmic islet cell antibody(ICA) in 82 cases of patients with IDDM was measuerd by standard indirect immunofluorescence technique. At same time,the peripheral blood T lymphoglocyte subsets in 35 cases of patients with IDDM were determined by means of series monoclonal antibodies. The results showed that the newly diagnosed IDDM patients were found to have higher incidence of positive serum ICA than patients who had longer than 6 months of illness(41.7% VS22.6%,), while CD3,CD8 positives cells were significantly lower than control(P< 0.01) and CD4/CD8 ratios apparently higher than control(P<0.01) in IDDM patients who had shorter than 6 months of illness. The results suggest the onset of IDDM may relate to autoimmune,and it is important to conduct the treatment of IDDM with immunosurpress as soon as possible.

采用O型血人新鲜胰腺冰冻切片作抗原,建立了血清胰岛细胞胞浆抗体(ICA)的间接免疫荧光测定法,对82例IDDM进行了血清胰岛细胞胞浆抗体检测,同时采用单克隆抗体技术,测定了35例IDDM患者外周血T细胞亚群。结果病程6个月以内的IDDMICA阳性率为41.7%,病程超过6个月为22.6%;病程6个月以内的IDDMCD3,CD8阳性细胞数明显低于对照组(P<0.01),CD4/CD8显著高于对照组(P<0.01),随着病程延长,这种变化逐渐消失。结果提示IDDM发病早期存在自身免疫失调,对IDDM免疫干预治疗应在发病早期进行。

Multiple sclerosis is the prototype inflammatory auto immune disorder of the central nervous system. In this article, we review the progress of research in immunological pathogenesis and intervention therapy in multiple sclerosis.

多发性硬化 (MS)是中枢神经系统 (CNS)自身免疫性疾病的代表。本文对多发性硬化的免疫发病机制和免疫干预治疗的研究进展作一概述。

Objective:To investigate the relationship between peripheral platelet count (PLT)and rheumatic arthritis(RA)disease activity.Methods :Clinical data of 111patients with RA were analyzed retrospectively.Patients were divided into two groups by PLT:high PLT group(PLT>300×10 9 /L)and normal PLT group(PLT≥100×10 9 /L and≤300×10 9 /L).Clinical manifesta-tion,laboratory examination,and remission of disease were compared between the two groups.Results:There were significant dif-ferences in fever,morning...

Objective:To investigate the relationship between peripheral platelet count (PLT)and rheumatic arthritis(RA)disease activity.Methods :Clinical data of 111patients with RA were analyzed retrospectively.Patients were divided into two groups by PLT:high PLT group(PLT>300×10 9 /L)and normal PLT group(PLT≥100×10 9 /L and≤300×10 9 /L).Clinical manifesta-tion,laboratory examination,and remission of disease were compared between the two groups.Results:There were significant dif-ferences in fever,morning stiffness,number of tender joints,number of swollen joints,hemoglobin level,erythrocyte sedimentation rate,C-reactive protein,rheumatoid factor,immunoglobulin(Ig)G,IgA,IgM and C3between the two groups.Increased PLT count was closely correlated with RA disease activity.But there was no re lationship between PLT count and cou rse of RA.Remission rate was lower in high PLT group than t hat of normal PLT group after treatme nt for one month(P<0.01).Conclusion:PLT count can be used as an effective criterion in evaluating RA disease activity if the influence of drugs can be excluded.PLT higher than450×10 9 /L suggests more severe RA which need s more potent immunosuppressive therapy.[

目的:探讨血小板计数与类风湿关节炎(RA)病情活动的相关性。方法:回顾性分析111例RA病例的临床资料,根据血小板计数分为血小板增高组(血小板超过300×109/L)与血小板正常组(血小板100×109/L~300×109/L),比较两组的病程、临床表现、实验室指标,并观察分析两组治疗后的病情缓解情况。结果:血小板增高组的发热、晨僵、压痛关节数、肿胀关节数、白细胞、血红蛋白、C反应蛋白、ESR、类风湿因子、IgG、IgA、IgM、C3与血小板正常组比较均有统计学差异,血小板计数增高与RA病情的活动密切相关,但与RA的病程无关。血小板增高组治疗1个月后的病情缓解率低于血小板正常组(P<0.01)。结论:除外药物不良反应的影响,血小板计数可作为评价RA病情活动和疗效的简便有效的指标之一。血小板超过450×109/L者,提示病情严重,宜加强免疫干预治疗

 
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