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   急性死亡率 的翻译结果: 查询用时:0.563秒
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急性死亡率
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  acute mortality
     Determination of Apparent Pharmacokinetic Parameters of 4-phenylbutanone-2 by Acute Mortality of Mice
     用小鼠急性死亡率法测定4-苯基丁酮-2的表观药动学参数
短句来源
     Determination of apparent pharmacokinetic parameters of anisodamine by acute mortality of mice
     用小鼠急性死亡率法测定山莨菪碱的表观药动学参数
短句来源
     Determination of Apparent Pharmacokinetic Parameters of Shengfu Injection by Acute Mortality of Mice
     小鼠急性死亡率法测定参附注射液药物动力学表观参数
短句来源
     7cm×12cm burn area was produced by 1 ml of 80% yellow phosphorus in rabbits and the acute mortality by this model was 50%. Serum phosphorus level was increased and the liver and kidney were damaged.
     家兔应用80%黄磷1ml,烧伤面积7cm×12cm,烧伤30s后立即用2%硫酸铜湿纱布灭火,此模型可造成磷烧伤家兔的急性死亡率为50%,伴血磷升高和肝、肾损害。
短句来源
     METHODS The toxicity of cantharidin was expressed at lethal dose 50 and biochemical indexes, apparent pharmacokinetic parameters of cantharidin were determined by using acute mortality of mice .
     方法 用小鼠半数致死量(LD50)及生化指标的变化来表征斑蝥素的毒性,用小鼠急性死亡率法测定斑螫素药物动力学参数。
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  “急性死亡率”译为未确定词的双语例句
     The results showed that there existed some correlations between the toxicological indexes and harmful chemical components in cigarette smoke,in which TSNA was the most important factor influencing MR value,SCE frequency and cell death rate(P<0.01),while the micronucleus frequency or death rate of mouse by secondhand smoke exposure was not correlated to tar,nicotine,CO,TSNAs and BaP(P>0.05).
     结果表明:卷烟烟气生物效应与烟气中重要有害化学成分之间存在一定的相关性,其中TSNA是影响MR值、SCE率和细胞死亡率最重要的因素(P<0.01),而微核率和被动吸烟小鼠急性死亡率与焦油、烟碱、CO、TSNA、BaP均无相关性(P>0.05)。
短句来源
     Effect of Cadmium on Mortality of Oxya chinensis Among Allozyme Genotypes
     中华稻蝗镉急性死亡率差异与等位酶基因型研究
短句来源
     Red kaolin was used to adsorb phosphorus in the burned region and mung bean soup, as a systemic therapeutic agent.
     创面应用赤石脂吸附磷,全身应用录豆汤治疗,可降低血磷,促进尿磷排泄,预防磷中毒,从而降低磷烧伤家兔的急性死亡率
短句来源
     was invertigated. The result readsas follows: hypnotic action of 1-menthol on pentobarbital had a evident dose-effect relationship. The pentobarbital solution with 4.5% 1-menthol can shorten thetime of falling asleep of mice (P<0.01), but the solutions with 1 .5% and 0.5% 1-menthol haveno significant effect on hypnotic action.
     研究薄荷醇经胃肠道给药对成巴比妥中枢抑制作用的影响,结果发现,薄荷醇对戊巴比妥的中枢抑制作用具有一定的量效关系,含4.5%的薄荷醇溶液可明显使小鼠的入睡时间缩恒,并使急性死亡率增加,而含1.5%和0.5%的薄荷醇溶液对成巴比妥的中枢抑制作用无明显影响。
短句来源
     Methods:The mortality and morphologic changes of human ovarian epithilial carcinoma cells were observed after HIFU with different intensity and sonication duration.
     方法 :观察人体卵巢上皮癌细胞受不同强度和时间的超声辐照后 ,肿瘤细胞的急性死亡率及肿瘤细胞的形态变化、增殖曲线和倍增时间。
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  相似匹配句对
     Long-term recurrence and death rates after acute pancreatitis
     急性胰腺炎的远期复发率和死亡率
短句来源
     The fatality rate was 3.17 %.
     急性中毒死亡率3.17%。
短句来源
     Acute Posterior Ischemic Optic Neuropathy
     急性后部缺血性视神经病变
短句来源
     Acute Mountain Sicknees
     急性高原病
短句来源
     MORTALITY OF MAMMALS
     兽类的死亡率
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  acute mortality
Death distribution after medium doses indicates that at least two mechanisms are involved in acute mortality.
      
None of the treatments affected the female preference for male pheromones or the male longevity except for the acute mortality caused by two-implant treatments.
      
Effects of cold ambient temperatures on acute mortality ofPeromyscus leucopus dosed with parathion
      
Only high doses resulted in acute mortality (>amp;gt;500 Gy) and decreased life span (>amp;gt;100 Gy).
      
Health impacts, especially acute mortality, dominate in term of costs.
      
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Apparent pharmaco-kinetic parameters of anisodamine, a postganglionic cholinergic blocking agent, were determined by acute mortality of animals. (1) The ip LD50 and 95 % confidence limit in mice were determined by Karber's method, and a log dose-death probit straight line (D-P line) was drawn, and then, an appropriate dose was selected according to the D-P line. (2) The chosen dose was given twice ip into groups of mice at an interval of 0.5, 1.0, 1.5, 2.0, 3.0, 4.0, 6.0, 8.0 or 12.0 hours. (3)The mortality...

Apparent pharmaco-kinetic parameters of anisodamine, a postganglionic cholinergic blocking agent, were determined by acute mortality of animals. (1) The ip LD50 and 95 % confidence limit in mice were determined by Karber's method, and a log dose-death probit straight line (D-P line) was drawn, and then, an appropriate dose was selected according to the D-P line. (2) The chosen dose was given twice ip into groups of mice at an interval of 0.5, 1.0, 1.5, 2.0, 3.0, 4.0, 6.0, 8.0 or 12.0 hours. (3)The mortality of each interval group given 2 dosages was recorded and its corresponding dose was found from the above-mentioned D-P line.Residual % after the first dosage=(Corresponding dose-Given dose/Given dose)×100%On the basis of "interval time-residual % relationship", a curve of dynamic change in residual % after initial dosage was drawn, to make the diagram would be a straight line in elimination phase by putting residual % in log. (4) Apparent rate con- stants were calculated by least-squares regression procedure and residual method. Pharmacokinetic parameters were calculated by phar-macokinetic formulas.By this method, distribution and elimination phase of a two compartment models can be seen before and after 1.5 hours respectively. Their pharmacokinetic parameters are: apparent rate constants of distribution phase and elimination phase, 3.608 h-1 and 0.238 h-1, respectively; the apparent residual % at zero hour of distribution phase and elimination phase, 200.2 and 35.9, respectively; their corresponding residual amounts, 529 mg/kg and 95 mg/kg, respectively; apparent half-lives of distribu-tion phase and elimination phase, 0.2 h and 2.9h, respectively; apparent AUC, 546mg·h/kg, apparent clearance, 0.48 kg/(kg·h), apparent distribution volume of center compartment Vc), 0.42 kg/kg; apparent distribution volume of peripheral compartment (vp), l.l0kg/kg; total apparent distribution volume(Vt), 1.53 kg/kg and apparent distribution volume of elimination phase (Vb), 2.04 kg/kg; apparent rate constants k12, k21 and k10, 1.952 h-1, 0.749 h-1 and 1.144h-1, respectively.

用小白鼠急性死亡率法测定了山莨菪碱ip时的经时过程和药动学参数。山莨菪碱在小鼠体内的经时过程为二室开放模型,1.5h之前为分布相,1.5h之后为消除相。用最小二乘法和残余量法求得α、β、A和B四项表现动力学参数分别为3.608h~(-1),0.238h~(-1),529mg/kg(200.2%)和 95mg/kg(35.9%);按药动学公式分别求得分布相表观半寿期(t_(1/2)α)和消除相表现半寿期(t_(1/2)β)为0.2h和2.9h,表观转运速率常数k_(12),k_(21)和k_(10)分别为1.952h~(-1),0.749h~(-1)和1.144h~(-1);表观曲线下面积(AUC)是546mg.h/kg;表观清除率(CI)是0.48kg/(kg.h),表观分布容积V_c,V_p,V_t,和V_b分别为0.42kg/kg,1.10kg/kg,1.53kg/kg和2.04kg/kg.

The general alkaloid of peganum could improve the clinical symptom of the cancer of the digestive tract. According to the principle that the plasma concentration, drug-effect and toxicity of most drugs are correlated, we combined the rule of the measurement of plasmaconcentration (in pharmacokineties) with the method of calculation of acute mortality of mice by means of drug-accumulation. Then using the probit of acute mortality of mice act as the index of pharmacological effect. The dose-effect curve was converted...

The general alkaloid of peganum could improve the clinical symptom of the cancer of the digestive tract. According to the principle that the plasma concentration, drug-effect and toxicity of most drugs are correlated, we combined the rule of the measurement of plasmaconcentration (in pharmacokineties) with the method of calculation of acute mortality of mice by means of drug-accumulation. Then using the probit of acute mortality of mice act as the index of pharmacological effect. The dose-effect curve was converted into the corresponding level in the body so that we conld know the metabolic rule of peganum alkaloid in body, calculate the main pharmacokinetic parameters and provide reference for clinical use.

骆驼蓬总生物碱,经临床验证能改善消化道肿瘤病人的临床症状。本文用骆驼蓬总生物碱注射液,依据大多数药物的血药浓度和药效、毒性呈平行关系这一原理。采用药物累积法,把药物动力学中血药浓度多点动态测定的原则与动物急性死亡率测定蓄积性的方法结合起来。以小鼠急性死亡率机率单位作为分级定量的药理效应指标,通过剂量效应曲线,转换成相应的体内药物水平。以了解骆驼蓬总碱注射液在动物体内的代谢规律,并推算其主要动力学参数,供临床用药参考。

7cm×12cm burn area was produced by 1 ml of 80% yellow phosphorus in rabbits and the acute mortality by this model was 50%.Serum phosphorus level was increased and the liver and kidney were damaged.Red kaolin was used to adsorb phosphorus in the burned region and mung bean soup, as a systemic therapeutic agent.The results suggest that they may promote phosphorus excretion from urine and decrease serum phosphorus level.

家兔应用80%黄磷1ml,烧伤面积7cm×12cm,烧伤30s后立即用2%硫酸铜湿纱布灭火,此模型可造成磷烧伤家兔的急性死亡率为50%,伴血磷升高和肝、肾损害。创面应用赤石脂吸附磷,全身应用录豆汤治疗,可降低血磷,促进尿磷排泄,预防磷中毒,从而降低磷烧伤家兔的急性死亡率。与对照组相比P<0.05。实验证明每克石脂可以吸附0.5g的磷酸。

 
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