助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   大鼠粪样 的翻译结果: 查询用时:0.021秒
图标索引 在分类学科中查询
所有学科
预防医学与卫生学
儿科学
更多类别查询

图标索引 历史查询
 

大鼠粪样
相关语句
  rat fecal samples
     Gas Chromatographic Analysis of C_1-C_6 Fatty Acids in Rat Fecal Samples
     大鼠粪样中C_1~C_6脂肪酸的分析
短句来源
  “大鼠粪样”译为未确定词的双语例句
     The ex-tractive efficiencies of C_-C_6 fatty acids from the fecalsamples were 88.5%-100%,and the recoveries rangedfrom 82.4%to 110.8%with the coefficients of varia-tion of 3.2%-10.9%。
     大鼠粪样中待测脂肪酸的提取效率为88.5%~100.0%,加标回收范围为82.4%~110.8%,变异系数为3.2%~10.9%。
短句来源
     A method was described for identification of scopolamine and its metabolites in rat feces by liquid chromatography and electrospray ionization tandem mass spectrometry(LC-ESI-MSn).
     用液相色谱-电喷雾串联质谱(LC-ESI-MSn)法检测东莨菪碱及其大鼠粪样中的代谢物。
短句来源
     RESULTS Totally,8 metabolites were detected in rats urine, 4 metabolites were detected in rats feces and 3 metabolites were detected in rats bile.
     结果在大鼠尿样中共检测到8种代谢物,在大鼠粪样中共检测到4种代谢物,在大鼠胆汁样品中共检测到3种代谢物。
短句来源
     A method is described for the identification of atropine and its metabolites in rat feces by combining liquid chromatography and tandem mass spectrometry (LC-MSn).
     应用液相色谱-电喷雾串联质谱(LC-MSn)法检测阿托品及其大鼠粪样中的代谢物。
短句来源
     Aim To establish a LC-MS~n method for the identification of anisodamine and its metabolites in rat feces.
     目的运用液相色谱-电喷雾串联质谱(LC-MSn)法检测大鼠粪样中山莨菪碱及其代谢物。
短句来源
更多       
  相似匹配句对
     Gas Chromatographic Analysis of C_1-C_6 Fatty Acids in Rat Fecal Samples
     大鼠中C_1~C_6脂肪酸的分析
短句来源
     Detection of anisodamine and its metabolites in rat feces by tandem mass spectrometry
     大鼠中山莨菪碱及其代谢物的串联质谱法检测
短句来源
     Determination of Anisodine and Its Metabolites in Rat Feces by Tandem Mass Spectrometry
     电喷雾串联质谱法检测大鼠中的樟柳碱及其代谢物
短句来源
     APXIVA gene couldn't be detected from dung.
     中不能检测到该基因。
短句来源
     Feces Analysis and Its Role in Wildlife Research
     在野生动物研究中的作用
短句来源
查询“大鼠粪样”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
没有找到相关例句


A gas chromatography procedure wasperformed to determine C_1-C_6 fatty acids in rat feces。Acidated fecal homogenate was extracted with ethylether-petroleum ether(1+1).After adding tetram-ethylammonium hydroxide to the extract , the quater-nary ammonium salts of the fatty acids could reactwith ethyl bromide in the Dresence of N,N-dimethylacetamide producing corresponding esters。 The derivedproducts were separated by the column packed withethylene glycol succinate polyester and were deter-mined with Flame ionizadon...

A gas chromatography procedure wasperformed to determine C_1-C_6 fatty acids in rat feces。Acidated fecal homogenate was extracted with ethylether-petroleum ether(1+1).After adding tetram-ethylammonium hydroxide to the extract , the quater-nary ammonium salts of the fatty acids could reactwith ethyl bromide in the Dresence of N,N-dimethylacetamide producing corresponding esters。 The derivedproducts were separated by the column packed withethylene glycol succinate polyester and were deter-mined with Flame ionizadon detector(FID).The ex-tractive efficiencies of C_-C_6 fatty acids from the fecalsamples were 88.5%-100%,and the recoveries rangedfrom 82.4%to 110.8%with the coefficients of varia-tion of 3.2%-10.9%。The detection limits were atlppm. The optimum conditions of esterification are dis-cussed.The method is safe and rapid,and has been ap-plied to the analysis of C_1-C_6 fatty acids in rat feces。

研究了一种大鼠粪样中C_1~C_6脂肪酸在室温下乙酯化的气相色谱分析方法,酸化的大鼠粪匀浆用乙醚-石油醚(1+1)振摇提取,提取液中的短链脂肪酸与四甲基氢氧化铰生成的季铵盐在二甲基乙酞胺溶剂中,于室温下与溴乙烷反应生成相应的乙酯。采用10%丁二酸乙二醇聚酯色谱柱,火焰离子化检测器测定C_1~C_6脂肪酸乙酯。大鼠粪样中待测脂肪酸的提取效率为88.5%~100.0%,加标回收范围为82.4%~110.8%,变异系数为3.2%~10.9%。对2g样品,各脂肪酸的检出限均可达1ppm。本文探讨了乙酯化反应的最佳条件,样品中C_1~C_6脂肪酸的衍生化反应在室温下1小时即可定量完成。所用试剂安全,操作简便,对实际样品的分析表明,本法适用于粪样中短链脂肪酸的测定。

Aim To establish a LC-MS~n method for the identification of anisodamine and its metabolites in rat feces.Methods Feces samples were collected after single administration of 25 mg·kg~(-1) anisodamine to rats,and dipped in water for 1 h.Samples were then extracted by ethyl acetate.The pretreated samples were separated on a reversed-phase C18 column using a mobile phase of methanol / 0.01% triethylamine(adjusted to pH 3.5 with formic acid)(60∶40,v/v) and detected by LC-MS~n.Identification of the metabolites and...

Aim To establish a LC-MS~n method for the identification of anisodamine and its metabolites in rat feces.Methods Feces samples were collected after single administration of 25 mg·kg~(-1) anisodamine to rats,and dipped in water for 1 h.Samples were then extracted by ethyl acetate.The pretreated samples were separated on a reversed-phase C18 column using a mobile phase of methanol / 0.01% triethylamine(adjusted to pH 3.5 with formic acid)(60∶40,v/v) and detected by LC-MS~n.Identification of the metabolites and elucidation of their structures were performed by comparing their changes in molecular masses(ΔM),retention-times and full scan MS~n spectra with those of the parent drug and blank feces.Results The parent drug and its seven metabolites(6β-hydroxytropine,nor-6β-hydroxytropine,aponoranisodamine,apoanisodamine,noranisodamine and hydroxyanisodamine,tropic acid) were found in rat feces.Conclusion This method is sensitive,rapid,simple,effective,and suitable for the rapid identification of drug and its metabolites in biologic samples.

目的运用液相色谱-电喷雾串联质谱(LC-MSn)法检测大鼠粪样中山莨菪碱及其代谢物。方法收集灌胃山莨菪碱(25 mg.kg-1)的大鼠粪样,用水浸泡后,以乙酸乙酯萃取,采用LC-MS及LC-MSn等方法检测原药及其代谢物。根据代谢物相对分子质量的变化(ΔM)及其多级质谱数据,鉴定并阐述其结构,同时与空白粪样及山莨菪碱相比较。结果在服药后的大鼠粪样中发现山莨菪碱及其7种代谢产物,分别为6β-羟基托品、N-去甲基-6β-羟基托品、N-去甲基脱水山莨菪碱、脱水山莨菪碱、N-去甲基山莨菪碱、羟基山莨菪碱以及托品酸等。结论该方法灵敏、快速、简便、有效,适合于生物样品中的药物及其代谢产物的快速鉴定。

A method is described for the identification of atropine and its metabolites in rat feces by combining liquid chromatography and tandem mass spectrometry (LC-MSn). The feces samples were collected after single administration of 25 mg/kg atropine to rats, and soaked in water for 1 h. Then, atropine and its metabolites were extracted by ethyl acetate. The extracted samples were separated on a reversed phase C18 column using a mobile phase of methanol/ammonium acetate (2 mmol/L, adjusted to pH 3.5 with formic acid)...

A method is described for the identification of atropine and its metabolites in rat feces by combining liquid chromatography and tandem mass spectrometry (LC-MSn). The feces samples were collected after single administration of 25 mg/kg atropine to rats, and soaked in water for 1 h. Then, atropine and its metabolites were extracted by ethyl acetate. The extracted samples were separated on a reversed phase C18 column using a mobile phase of methanol/ammonium acetate (2 mmol/L, adjusted to pH 3.5 with formic acid) (70∶30, V/V) and detected by LC-MSn. By comparing retention-times, full scan MS and MS2 spectra among extracts, parent drug and blank feces, metabolite structures were deduced: nortropine, tropine, tropic acid, aponoratropine, apoatropine, noratropine, hydroxyatropine, hydroxyatropine N-oxide and hydroxy-methoxyatropine. This method is rapid, convenient, and suitable for the rapid identification of drug metabolites in biologic samples.

应用液相色谱-电喷雾串联质谱(LC-MSn)法检测阿托品及其大鼠粪样中的代谢物。收集灌胃25mg/kg阿托品的大鼠粪样,以水浸泡后,用乙酸乙酯萃取,采用LC-MS及LC-MSn等方法检测原药及其代谢物。和空白粪样及阿托品相比较,依据保留时间、一级质谱和二级质谱数据,在服药后的大鼠粪样中发现9种代谢物,分别为托品、N-去甲基托品、N-去甲基脱水阿托品、脱水阿托品、N-去甲基阿托品、羟基阿托品、N-氧化阿托品、羟基甲氧基阿托品以及托品酸等。该方法快速,简便,适合于生物样品中药物代谢物的快速鉴定。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关大鼠粪样的内容
在知识搜索中查有关大鼠粪样的内容
在数字搜索中查有关大鼠粪样的内容
在概念知识元中查有关大鼠粪样的内容
在学术趋势中查有关大鼠粪样的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社