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静脉输注
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  intravenous infusion
     However,the elevated OT secretion in response to hypotension induced by intravenous infusion of sodium nitroprusside was dose dependently augmented by icv injection of 5 μL L NAME (dose 1:27 0 g/L,n=9;dose 2:54 0 g/L,n=8).
     侧脑室内注射 5μL L- NAME(剂量 1 :2 7.0 g/L,n=9;剂量 2 :54.0 g/L,n=8) ,可进一步增强静脉输注硝普钠引起低血压所诱导的 OT分泌升高反应。
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     Anesthesia was induced routinely,and it was maintained by continuous intravenous infusion of remifentanil of 0.1 μg/(kg·min)(group A),remifentanil of 0.3 μg/(kg·min)(group B),and fentanil of 0.03 μg/(kg·min)(group C) and by inhalation of isoflurane and nitrous oxide in oxygen(2∶1).
     常规麻醉诱导,麻醉维持每分钟A组瑞芬太尼0.1μg/kg,B组瑞芬太尼0.3μg/kg,C组芬太尼0.0 3μg/kg,持续静脉输注并吸入异氟醚和O2∶N2O(2∶1)。
短句来源
     Esmolol was given as bolus 0.5 mg/kg followed by continuous intravenous infusion at 0.05mg · kg-1 · min-1 and can be titrated to 0.2 mg · kg-1 ? min-1 without increase of bolus.
     艾司洛尔静脉负荷量0.5mg/kg,1分钟内静注,继以0.05mg·kg~(-1)·min~(-1),持续静脉输注,若无效,4分钟后静脉负荷量不变,维持量递增,直至0.2mg·kg~(-1)·min~(-1)。
短句来源
     Different levels of blood pressure were obtained by long term (six days) intravenous infusion of different concentrations (0 3%~8%) of NaCl solution to normal SD rats.
     三组SD大鼠分别静脉输注不同浓度 (0 3% ,4%及 8% )NaCl溶液以使其处于不同的血压水平。
短句来源
     Results PaO_2 and PaO_2/FiO_2 in 25 cases increased after 1h and 3 h of intravenous infusion of oxygen-enriched liquid (P<0.01 for each).
     结果在静脉输注高氧液1h和3h后,有25例患者动脉血氧分压(PaO2)升高明显(P<0.01),氧合指数改善明显(P<0.01);
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  venoclysis
     Venoclysis of alanyl-glutamine 20 g/d for 7 days were administered continuously during the acute phase in the glutamine group. Then their scores of neurological deficit and nutritive indexes at day 7,14,and 28 were recorded. At the same time,the occurrence and duration of infective complications were recorded.
     谷氨酰胺组在急性期连续7 d静脉输注丙氨酰-谷氨酰胺20 g/d,随后记录7、14、28 d的神经功能缺损评分及营养学指标,同时记录感染性并发症的发生及持续时间。
短句来源
     Sodium bicarbonate to alkalinize urine and venoclysis of 5% glucose solution for hydration were used during therapy.
     治疗期间用碳酸氢钠硷化尿液,静脉输注5%葡萄糖水化。
短句来源
     MethodsThirty-four patients with hypertension underwent general anesthesia were randomly divided into the control group and the puerarin group, 500mg puerarin was given to the puerarin group 1h r before anesthesia induction by venoclysis and to the control group, normal sal ine was given instead.
     方法34例原发性高血压全麻患者,随机均分为葛根素组和对照组,分别于诱导前1h静脉输注中药葛根素注射液500mg和生理盐水。
短句来源
     Methods: Forty five patients, ASA gradeⅠ~Ⅱ, scheduled for elective hysterectomy, were randomly divided into 3 groups continuous epidural analgesia(CEA),continuous venoclysis analgesia(CVA) and meperidine muscle analgesia(MA) groups.
     方法 :4 5例ASAⅠ~Ⅱ级择期子宫切除术患者。 随机分为持续硬膜外输注镇痛 (CEA)组、持续静脉输注镇痛 (CVA )组和传统哌替啶肌注镇痛 (MA)组 ,每组 15例。
短句来源
     Clinical observation of therape-utic effects Venoclysis Hyperoxia solution on acute cerbral infarction
     静脉输注高氧液治疗急性脑梗死的疗效观察
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  phleboclysis
     Objective:To assess the efficacy of phleboclysis of encephalitis B virus neutralizing antibody positive plasma in patients with epi- demic encephalitis B.Methods:42 children with the onset of epidemic encephalitis B within 5 days,were treated with neutralizing antibody in the day and the next day when they were hospitalized,with the dose of 5ml·kg~(-1) and time only given and at the same time,were given standard combination theraphy.
     目的:了解静脉输注流行性乙型脑炎(乙脑)病毒中和抗体阳性血浆治疗乙脑的疗效。 方法:对42例发病5 d 内的乙脑患儿入 院当日及次日各静脉给予1次乙脑病毒中和抗体阳性血浆,每次每公斤体重给予5ml,同时给予综合治疗;
短句来源
  “静脉输注”译为未确定词的双语例句
     Group R_1 received 0.05μg·kg~-1·min~-1 remifentanil intravenously, and group R_2 received 0.1μg·kg~-1·min~-1 remifentanil intravenously.
     R_1组为瑞芬太尼0.05μg·kg~(-1)·min~(-1)速度静脉输注; R_2组为瑞芬太尼0.1μg·kg~(-1)·min~(-1)速度静脉输注
短句来源
     5×107 C57BL/6 splenocytes were transfused into F1 (Balb/C×C57BL/6, H-2b/d) via tail vein to develop GVHR model.
     经静脉输注C57BL/6(H-2b)脾细胞给F1代小鼠(C57BL/6×Balb/cH-2b/d),建立移植物抗宿主病模型。
短句来源
     C2 group was that C57BL/6 mice were infused by BMCs and SCs of chimeras rats in Bl group.
     C2组是给C57BL/6小鼠经尾静脉输注B1组嵌合大鼠BMCs和SCs;
短句来源
     Successively, analgestic pump containing combined Tramadol that included Tramadol (15 mg/kg), Droperidol (0.15 mg/kg), Midazolam (0.4 mg/kg) and 100 ml 10 g/L Procaine was used for 50 hours, (1.5-2.5) ml/h, continuously.
     续接镇痛泵内配制的曲马多合剂曲马多15mg/kg、氟哌利多0.15mg/kg、咪唑安定0.4mg/kg,10g/L普鲁卡因加至100ml,一个镇痛泵可持续静脉输注50h(1.5~2.5ml/h),本组用药时间为40~160h。
短句来源
     In the type 1 diabetic rats, plasma glucose concentrations were(17.04±1.31) mmol/L (P<0.05) after 60 min by intravenous injection rhGLP-1(7-36)NH 2, and glucose concentrations were(11.98±1.05) mmol/L (P<0.001) after 120 min.
     静脉输注rhGLP 1(7 36 )NH2 6 0min后 ,血糖水平 (17.0 4± 1.31)mmol/L(P <0 .0 5 ) ,12 0min后血糖水平 (11.98± 1.0 5 )mmol/L(P <0 .0 0 1)。
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  intravenous infusion
Because of rapid and high volume intravenous infusion we avoided hypovolemic shock.
      
Methods Fifteenmin prior to clamping of the abdominal aorta, 13 organ donors were treated with 15mg P (Arelix?) intravenous (infusion time: 10min).
      
Cessation of triggering agents, increased ventilation and oxygenation with 100% O2, and intravenous infusion of dantrolene, an inhibitor of sarcoplasmic Ca2+ efflux, is the basis of causative therapy.
      
High dose of norepinephrine was given by intravenous infusion.
      
Abciximab was administered in bail-out situations in a dosage of 0.25mg/kg given as a bolus, which was followed by an intravenous infusion of 10μg/min over 12 hours.
      
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  venoclysis
Venoclysis of upper limb was performed in the operating room and lactated Ringer's solution infusion was started.
      
Venoclysis in upper limb was performed in the operating room and lactated Ringer's solution infusion was started.
      
  phleboclysis
Subsequently, phleboclysis was performed so that a lethal dose of potassium chloride could be administered.
      


The time required to obtain steady-state plasma level by intravenous infusion will be quite long for a drug with a long half-life. It may be convenient in such cases to administer an intravenous loading dose to attain immediately the desired drug concentration and then attempt to maintain this concentration by continuous infusion.Equations (1) and (2) describing the dosage regimen of intravenous infusion of two-compartment model drugs were given by Boyes in 1971.X_0=C_(ss)·V_c (1)k_0=C_(ss)·V_c·k_(10) (2)where...

The time required to obtain steady-state plasma level by intravenous infusion will be quite long for a drug with a long half-life. It may be convenient in such cases to administer an intravenous loading dose to attain immediately the desired drug concentration and then attempt to maintain this concentration by continuous infusion.Equations (1) and (2) describing the dosage regimen of intravenous infusion of two-compartment model drugs were given by Boyes in 1971.X_0=C_(ss)·V_c (1)k_0=C_(ss)·V_c·k_(10) (2)where X_0 is the loading dose, k_0 is the zero-order rate constant of intravenous infusion, Css is the steadystate plasma level which may be adjusted to the desired plasma concentration for clinical treatment, V_c is the volume of central compartment, and k_(10) is the first-order elimination rate constant from the central compartment.The plasma level from this dosage regimen is slightly lower than that of the desired plasma level.In 1972, Mitenko presented the following equations:X_0=(k_(10))/β·C_(ss)·V_c (3)k_0=C_(ss)·V_c·k_(10) (4)In equation (3) and (4) β is the slow disposition rate constant, and the other symbols are defined as previously described.The plasma level of this dosage regimen is higher than that of the desired plasm level.Considering the advantages and shortcomings of these two dosage regimens, the author derived the following equations:X_0=((1/α)+(1/β)-((k_(10))/(αβ)))·k_(10)·C_(ss)·V_c (5)K_0=C_(ss)·V_c·K_(10) (6)where α is the fast disposition rate constant.From this dosage regimen, the author obtained the equation of plasma level-time curve:where t is the time of intravenous infusion, C_t is the plasma level at time t.The advantage of this dosage regimen was theoretically evaluated.

静脉输注是临床上广泛用于抢救危重病例的一种有效的给药方法,缺点是开始输注时血药浓度偏低。为了使血药浓度迅即达到临床治疗的最佳有效血药浓度,有一种简便易行的方法是在开始时立即静注一个底药剂量,同时以恒定速度进行静脉输注,以维持该血药浓度。这种静脉输注方案的关键问题在于采用何种底药剂量和以何种速度静脉输注。对于双室模型的药物,1971年及1972年Boyes及Mitenko先后提出了两种不同的静脉输注方案。本文用组合曲线求组合常数的方法推导出了介于上述两种方案之间的一种新的静脉输注方案,给出了这种新方案的“血药浓度一时间”曲线公式,并从理论上证明这种方案的优越性。

During 1978-1981,18 patients with malignant lymphoma in Stage Ⅲ-Ⅳ(16 lym- phosarcoma,2 Hodgkin's Disease,1 reticulum cell sarcoma),which had become resis- tant to chemotherapy and radiotherapy,were treated with moderately high doses of methotrexate(MTX)plus citrovorum factor(CF).All of these cases were confirmed by histopathology.MTX used was from 0.2 to 1.0 gm followed in 24 to 36 hours by CF 6 mg q6h for 2-3 days.Sodium bicarbonate to alkalinize urine and venoclysis of 5% glucose solution for hydration were...

During 1978-1981,18 patients with malignant lymphoma in Stage Ⅲ-Ⅳ(16 lym- phosarcoma,2 Hodgkin's Disease,1 reticulum cell sarcoma),which had become resis- tant to chemotherapy and radiotherapy,were treated with moderately high doses of methotrexate(MTX)plus citrovorum factor(CF).All of these cases were confirmed by histopathology.MTX used was from 0.2 to 1.0 gm followed in 24 to 36 hours by CF 6 mg q6h for 2-3 days.Sodium bicarbonate to alkalinize urine and venoclysis of 5% glucose solution for hydration were used during therapy.The total dose of MTX varied from 200 to 4,800 mg.The overall response rate was 72%(13/18) (7 PR,6 CR) and for lymphosarcoma 80%(12/15);by Karnofsky performance status,the improve- ment rate was 89%(16/18).The main side effects of MTX-CF in this series were leu- kopenia,thrombocytopenia,elevation of SGPT,nausea and vomiting,oral ulcer,skin rash and tetany;all were acceptable and reversible.There was no instance of renal dysfunction or death due to the use of this drug.

天津市人民医院化疗科,1978~1981年用中等量氨甲喋呤治疗各种化疗放疗失效的晚期恶性淋巴瘤18例,其中淋巴肉瘤15例,何杰金氏病2例,网织细胞肉瘤1例。全经病理学确诊。采用MTX 连续序贯疗法,单次剂量0.2—1gm,CF6mg 每6小时一次,连用2~3天。治疗期间用碳酸氢钠硷化尿液,静脉输注5%葡萄糖水化。本组病例显效7例有效6例,近期有效率达72%(13/18),其中淋巴肉瘤有效率达80%(12/15)。根据 Karnofsky 体力状况指标分析,体力状况改善率达89%(16/18)。本组常见的副作用为白细胞,血小板减少,SGPT 升高,恶心、呕吐及口腔溃疡。少数病人出现皮疹及手足抽搐,均为可逆。没有出现肾功能损害的病例,亦无与药物治疗有关的死亡。

The results of cryopreservation of bone marrow cells by three different techniques were compared. It was shown that by using the mixture of alcohol and dry ice, liquid nitrogen container, or KSL-811 type of freezing rate control equipment, the viability of hemopoietic stem cells either of bone marrow origin or from fetal liver was the best. The rate of fre-ezing was controlled at 0-3℃/min. The thawed bone marrow suspension containing 5 or 10% dimethylsulfoxide was safe to infuse intravenously into animal and...

The results of cryopreservation of bone marrow cells by three different techniques were compared. It was shown that by using the mixture of alcohol and dry ice, liquid nitrogen container, or KSL-811 type of freezing rate control equipment, the viability of hemopoietic stem cells either of bone marrow origin or from fetal liver was the best. The rate of fre-ezing was controlled at 0-3℃/min. The thawed bone marrow suspension containing 5 or 10% dimethylsulfoxide was safe to infuse intravenously into animal and man without inducing harmful side effects.

本文介绍了酒精加干冰、半自动液氨生物容器降温装置和KSL-811型可控速率冷冻装置3种骨髓超低温保存技术。实验与应用结果表明,冷冻速度在3℃/min以内均可保持造血干细胞活力,将含10%和5%二甲基亚砜的骨髓细胞悬液直接静脉输注给动物和人,未见明显的毒副作用。

 
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