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二氯乙烷
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  “2-二氯乙烷”译为未确定词的双语例句
    Effect of 1.2-dichloroethane on blood brain barrier
    1,2-二氯乙烷对血脑屏障的损伤作用
短句来源
    Determination of 1,2-dichloroethane in urine with static headspace gas chromatography
    顶空气相色谱法测定尿中1,2-二氯乙烷
短句来源
    Objective To investigate the effect of 1,2-dichloroethane(1,2-DCE)on blood brain barrier.
    目的探讨1,2-二氯乙烷对血脑屏障的损伤作用。
短句来源
    1,2-Dichloroethane had a good linearity(r=0.9980) within 0~20.0mg/L. The average recovery was 97.2% and 94.1%,with the RSD of 5.18% and 6.58%.
    结果本方法最低检出浓度为0.52 mg/L,1,2-二氯乙烷在0~20.0 mg/L范围内有良好线性(r=0.9980),平均回收率为97.2%及94.1%,RSD值为5.18%及6.58%。
短句来源
    Conclusions: The method is simple,rapid and accurate and can be used in determination of 1,2-Dichloroethane in urine.
    结论本方法简便、快速、准确,能用于尿中1,2-二氯乙烷的测定。
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Objective To investigate the effect of 1,2-dichloroethane(1,2-DCE)on blood brain barrier. Methods Acute toxic encephalopathy model was copied with the consecutive static inhalation of 1,2-DCE.The water content of brain tissue was measured,and the blood brain barrier permeability was detected with lanthanum nitrate.The brain microvascular endothelial cells and neuroglial cells were cultured in vitro,which were administrat- ed with 1,2-DCE.The cell morphologic structures were observed under light microscope and...

Objective To investigate the effect of 1,2-dichloroethane(1,2-DCE)on blood brain barrier. Methods Acute toxic encephalopathy model was copied with the consecutive static inhalation of 1,2-DCE.The water content of brain tissue was measured,and the blood brain barrier permeability was detected with lanthanum nitrate.The brain microvascular endothelial cells and neuroglial cells were cultured in vitro,which were administrat- ed with 1,2-DCE.The cell morphologic structures were observed under light microscope and electron microscope. Results (1)The extracellular edema was most found in the cerehral tissue and the leakage of lanthanum particles through the barrier were found with the lanthanum tracking method.(2)The water content in cerebral cortex in the moderate and high dose groups was significantly higher than that in the control group and became severer with the increases of the intoxicated time.The water content in cerebral medulla was significantly increased only at 6 hours after the intoxication.(3)The normal morphological structure of brain microvascular endothelial cells and neuroglial cells could be injured by 1,2-DCE,And the injury to neuroglial cells caused by 1,2-DCE occurred earlier and sev- erer than that to brain microvascular endothelial cells.Conclusion 1,2-DCE can damage blood brain barrier and induce cerebral edema.

目的探讨1,2-二氯乙烷对血脑屏障的损伤作用。方法用1,2-二氯乙烷静式呼吸道急性染毒复制大鼠急性中毒性脑病模型,用硝酸镧染色法测定脑组织的含水量并检测血脑屏障的通透性;同时在体外培养脑微血管内皮细胞和神经胶质细胞,用1,2-二氯乙烷对生长良好的脑微血管内皮细胞和神经胶质细胞染毒,在光镜和电镜下观察细胞形态学特征。结果(1)脑组织主要表现为细胞外水肿,镧示踪法检测到血脑屏障有镧颗粒的大量渗漏。(2)中高剂量染毒组大鼠大脑皮质含水量较对照组明显升高,并且随着染毒后时间的延长更趋严重;大脑髓质含水量仅在染毒后观察6 h组有统计学意义(P<0.05)。(3)1,2-二氯乙烷能破坏脑微血管内皮细胞和神经胶质细胞的正常形态学结构,且对神经胶质细胞的损伤表现得较早、较严重。结论1,2-二氯乙烷可造成血脑屏障的损伤,引起血管源性脑水肿。

Objective To study the assay method of 1,2-dichloroethane in urine with static headspace gas chromatography and the biomarker of 1,2-dichloroethane exposure.Methods: 1,2-dichloroethane in urine was determined with static headspace gas chromatography with SE-30 column at 85℃ and detected with flame ionization detector(FID).Results: The minimum of determination concentration was 0.52mg/L.1,2-Dichloroethane had a good linearity(r=0.9980) within 0~20.0mg/L.The average recovery was 97.2% and 94.1%,with the RSD of...

Objective To study the assay method of 1,2-dichloroethane in urine with static headspace gas chromatography and the biomarker of 1,2-dichloroethane exposure.Methods: 1,2-dichloroethane in urine was determined with static headspace gas chromatography with SE-30 column at 85℃ and detected with flame ionization detector(FID).Results: The minimum of determination concentration was 0.52mg/L.1,2-Dichloroethane had a good linearity(r=0.9980) within 0~20.0mg/L.The average recovery was 97.2% and 94.1%,with the RSD of 5.18% and 6.58%.Conclusions: The method is simple,rapid and accurate and can be used in determination of 1,2-Dichloroethane in urine.

目的建立尿中1,2-二氯乙烷的顶空气相色谱测定方法。方法将样品置于密闭的顶空瓶内,采用SE-30色谱柱(2 m×3mm),在85℃进行分离,氢火焰离子化检测器检测(150℃),气化室温度150℃;载气(氮气)流速30 mL/m in,空气流速300mL/m in,氢气流速30 mL/m in,对尿中1,2-二氯乙烷进行测定。结果本方法最低检出浓度为0.52 mg/L,1,2-二氯乙烷在0~20.0 mg/L范围内有良好线性(r=0.9980),平均回收率为97.2%及94.1%,RSD值为5.18%及6.58%。结论本方法简便、快速、准确,能用于尿中1,2-二氯乙烷的测定。

 
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