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Objective: To explore the rational use of FK506 clinically.Methods:Regular sampling of early morning blood was collected for detection of FK506 concentration after simultaneous pancreas kidney transplantation.The blood level of FK506 was assayed with MEIA.Results:It was found that there was not close correlation between the FK506 dosge and the concentration of FK506 (Y^=2.35+1.0x^, r =0.4275, P <0.05).Conlution:After simultaneous pancreas kidney transplantation,the FK506 concentration in blood should... Objective: To explore the rational use of FK506 clinically.Methods:Regular sampling of early morning blood was collected for detection of FK506 concentration after simultaneous pancreas kidney transplantation.The blood level of FK506 was assayed with MEIA.Results:It was found that there was not close correlation between the FK506 dosge and the concentration of FK506 (Y^=2.35+1.0x^, r =0.4275, P <0.05).Conlution:After simultaneous pancreas kidney transplantation,the FK506 concentration in blood should be monitored on a routine basis and its dosage should be adjusted accordingly. 目的 :为临床胰 -肾移植患者他可莫司 (FK5 0 6 )的合理使用提供参考。方法 :采用单抗微珠酶联免疫吸附试验 (MEIA)法对胰 -肾联合移植的患者术后全血FK5 0 6浓度进行动态监测 ,并对其结果进行分析。结果 :药量与血药浓度二者呈正相关 ,但相关关系不密切 (Y^ =2 .35 +1.0x^ ,r =0 .4 2 75 ,P <0 .0 5 )。结论 :胰 肾移植术后应常规性的监测FK5 0 6血药浓度 ,随时调整其合理用量。 Objective To evaluate the inoact of low immune function and the pure red cell aplasia (PRCA) in patients with simultaneous pancreas-kidney transplantation. Methods The peripheral cell subsets, parvovirus B19 and bone marrow sample were detected. Antivirus, decreasing immunosuppressant and transfusing pure red cell were performed in 2 cases in Dec 1998. Results 2 patients with PRCA recovered in 2 weeks and 3 weeks respectively and none of them was recurrent. Conclusion PRCA may be induced in the old patient with... Objective To evaluate the inoact of low immune function and the pure red cell aplasia (PRCA) in patients with simultaneous pancreas-kidney transplantation. Methods The peripheral cell subsets, parvovirus B19 and bone marrow sample were detected. Antivirus, decreasing immunosuppressant and transfusing pure red cell were performed in 2 cases in Dec 1998. Results 2 patients with PRCA recovered in 2 weeks and 3 weeks respectively and none of them was recurrent. Conclusion PRCA may be induced in the old patient with suppressed immune function, parvovirus B19 infection and immunosuppressant. Treating PRCA with combined therapy is efficient. 目的 探讨高龄胰肾联合移植病人免疫抑制低下与发生纯红细胞再障(PRCA)的关系。方法 1998年12月,5例胰肾移植患者中2例并发PRCA及自身免疫溶血性贫血,监测微小病毒B_(19),T_4/T_8比值及骨髓象。采用调整免疫抑制剂、抗病毒、输注红细胞等综合疗法。结果 2例PRCA患者分别于2周、3周骨髓象恢复正常,并观察1年以上无复发。结论 高龄、免疫力低下、微小病毒B_(19)感染、免疫抑制药物易诱发PRCA,临床综合治疗是有效措施。
胰肾移植
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Harvesting of combined pancreas and kidney for the treatment of type Ⅱ diabetes with renal failure 联合快速切取胰肾移植治疗Ⅱ型糖尿病肾功能衰竭 短句来源 Methods The peripheral cell subsets, parvovirus B19 and bone marrow sample were detected. 方法 1998年12月,5例胰肾移植患者中2例并发PRCA及自身免疫溶血性贫血,监测微小病毒B_(19),T_4/T_8比值及骨髓象。 短句来源 相似匹配句对
Clinical experience in the simultaneous pancreas-kidney transplantation 胰肾联合移植的体会 短句来源 Rejection in simultaneous pancreas-kidney transplantation 胰肾联合移植的排斥反应 短句来源 A Model Establishment of CombinedPancreas-Kidney Transplantation in Dog 胰肾联合移植的实验研究 短句来源 Simultaneous pancreas-kidney transplantation. 胰肾一期联合移植 短句来源 Nursing of patients with kidney-pancreas transplantation 胰肾联合移植患者的护理 短句来源 
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In the most popular patient group (simultaneous pancreas-kidney transplantation, SPK) the graft-function rate at 1 year now reaches more than 80 %.
Thus, simultaneous pancreas-kidney transplantation can be performed with a high success rate when using the technique described.
Rehabilitation and quality of life in diabetic patients after successful pancreas-kidney transplantation
Twenty-seven Type I diabetic patients in end-stage renal failure were followed after combined pancreas-kidney transplantation.
We conclude that, despite prednisone-induced insulin resistance, normal glucose tolerance is achieved by hyperinsulinaemia and normalisation of glucose-dependent glucose disposal following pancreas-kidney transplantation in Type 1 diabetic patients.
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