1. The Experimental Study of rALR on Immunologic Response Induced by Exogenous Antigen in Rat 2. Analysis on Cause of Death in 115 Patients with Hepatic Failure Induced by Viral Hepatitis 3. The Primary Clinical Study of Peginterferon Alfa-2a in the Treatment the Patients with HBeAg-Positive Chronic Hepatitis B and with Drug Fast to Lamivudine
The serum sIL-2R levels in patients with acute viral hepatitis (icteric stage), chronic active hepatitis and severe hepatitis were 129.36 + 37.15 u/ml, 174.44 + 91.90 u/ml and 245.00 +77.67 u/ml, which were significantly higher than in normal control group (72.67 +43.46 u/ml)(p<0.01).
The mean loads of HCV RNA in liver cirrhosis and hepatocelluar carcinoma patients were significantly higher than those in chronic hepatitis patients (7.75±0.29, 7.86±0.32 vs 4.67±0.41, P<0.05), and there was also a positive correlation between HCV RNA loads and ALT level (r= 0.89,t= 8.29, P<0.05).
在HCV抗体阳性患者中, 肝硬化和肝癌患者的HCV RNA含量显著高于慢性肝炎患者(7.75±0.29,7.86±0.32 vs 4.67±0.41,P<0.05), 而且HCV RNA含量与ALT水平呈正相关(r=0.89, t=8.29,P<0.05).
This study evaluates the survival outcomes of patients who underwent living-donor liver transplantation (LDLT) using right lobe liver grafts for fulminant liver failure due to hepatitis B infection.
Expression and Characterization of Hepatitis B Surface Antigen in Transgenic Potato Plants
Transgenic potato plants expressing the gene of hepatitis B surface antigen (HBsAg) under the control of the double promoter of 35S RNA of cauliflower mosaic virus (CaMV 35SS) and the promoter of patatin gene of potato tubers have been obtained.
The molecular weight of HBsAg peptide was approximately 24 kD, which is in agreement with the size of the major protein of the envelope of hepatitis B virus.
Therefore, as well as in recombinant HBsAg-yeast cells, assembling of HBsAg monomers into immunogenic aggregates takes place in HBsAg-transgenic potato, which can be used as a source of recombinant vaccine against hepatitis B virus.