Objective To evaluate pseudophakic accommodation in subjects implanted with the 1CU accommodative intraocular lens (AIOL) by measuring the visual acuity, the changes in anterior chamber depth (ACD) and pupillary diameter (PD) under drug-induced stimulation in comparison with a foldable monofocal AKREOS ADAPT IOL.
[Objectives]The aims of our study were to evaluate the feasibility of CEU used in assessing and monitoring of CBF, and to detect the changes of cerebral perfusion of the dogs under different pathologic conditions such as normal, hypercapnia, hypocapnia, acute cerebral ischemia, drug-induced acute hypertension and hypotension.
Otherwise, Sigmorini and his assistants cultivated the mutated rat that is lack of the GIRK protein in 1997. Similar with Weavor rat is that they are more sensitive to spontaneous or drug induced seizure, they display that the GIRK1 and GIRK2 decreased significantly.
Conclusions K562 and K562/VCR cells have defferent sensitivity to vincristine induced apoptosis. The resistance of drug resistant leukemic cells to drug induced apoptosis may play an important role in multidrug resistance of leukemia.
RESULTS: (1)With drug inducing time increasing, the volume of the differentiated cells was enlarged gradually. After 72 hours, the differentiated cells began to express differentiating marker CD11b and the nuclei morphology of the differentiated cells was changed.
(2)After 96 hours of drug inducing, the induced cells began to show apoptosis peak, but when the cells was washed once after 72 hours of drug inducing with RPMI 1640 medium and resuspended in RPMI 1640 medium supplemented with 10%fetal calf serum and then cultured in 5%CO2, 37℃for 8 hours,the cells began to show apoptosis peak,and the apoptosis peak was higher than that of the cells after 96 hours of drug inducing.
Clinical analysis of 275 cases of acute drug-induced liver disease
The proportion of acute drug-induced liver disease among all of the acute liver injuries was annually increased.
The clinicians should pay attention to the prevention, diagnosis and therapy of drug-induced liver disease.
The high level of 36Cl- conductivity during nonconvulsive pentylenetetrazole-induced kindling suggested that the activity of the GABAA receptor was similar in the genetic and drug-induced models of the absence epilepsy.
This result implied that the decrease of 5-HT might be the basis of rotating constant magnetic field (RCMF) inhibiting drug-induced emesis.
Antithyroidal drug-treatment was stopped two weeks prior to admission under the assumption of drug induced thrombozytopenia.
It is a consequence of impaired antimicrobial defence during drug induced bone marrow suppression.
Class-III drugs inhibiting selectively the rapidly activating and deactivating IKr component exhibit a marked reverse rate dependence, i.e., the drug induced prolongation of the cardiac action potential is minimized at high rates.
The drug induced a complete reversal of the adenosine to inosine ratio during ischemia and a remarkable prolongation of the accumulation within the tissue of mainly adenosine during early reperfusion and inosine afterwards.
A 44 year old woman with a severe drug induced tardive dyskinesia had previously been treated with a left thalamotomy and right deep brain stimulation.
Urinary 6β-hydroxycortisol: a validated test for evaluating drug induction or drug inhibition mediated through CYP3A in humans a
6β-Hydroxycortisol (6β-OHF) urinary excretion has, for a long time, been considered a marker of drug induction and, more recently, of drug inhibition in humans and in laboratory animals, but its specificity is still under debate.
Patients with stage I and II received an 8-drug induction followed by a consolidation including high-dose-methotrexate (MTX) and maintenance therapy up to a total therapy duration of 24 months.
Deletion of the region containing the five XREs, XRE(-6) to XRE(-2), and the point mutation of XRE(-1) reduced the inducible expressions by 75% and 56%, respectively, showing apparent dependency of the drug induction on the XREs.
To assess the regulation of cell cycle modulators, western blot analysis of H1299 cell lysates showed the release of apoptosis initiator, cytochrome c and apaf-1 hours following drug induction.