Conclusion: ET-1、CGRP、TNF-α and IL-8 were important indexs which reflected the degree of liver damage and estimated the prognosis in posthepatitic cirrhosis.
Compared with the SLE patients without HCV infection, the patients with HCV infection had a lower rate of cutaneous SLE features and dsDNA positivity (P=0.01 and P<0.001), but with higher incidences of hepatic damage (P<0.001) and low levels of C4 and CH50 (P=0.01 and P=0.03) as well as cryoglobulins levels (P=0.03).
The efficacy rate of hepatic damage was 12.65% , 15.97% of patients less than 1 year old and 9.72% for those more than 1 year old, showed significant difference (P< 0.05) .
The rate of sex, age, course of disease, serum IgG, IgA, ANA, C3,anti-SSA, anti-SSB, anti-RNP and RF in patients with liver involvement did not show any difference from those without liver involvement(P>0.05).
Conclusion:The cases of rotavirus enteritis maybe combine with hepatic lesion,increase in ALT and AST are most frequently observed. The prognosis is fairly good after antivirus and protecting hepatic therapy,most of the sick children could recover from hepatic function lesion and hepatic tumefaction within 2 weeks.
Since leukocytes are much more available than hepatocytes or neuronal cells in humans, we assume that CE in peripheral blood leukocytes (neutrophils and monocytes) can be used as markers for indication of pending liver damage by CPZ.
In this study, we examined the effects of its ethanolic root extract on experimental liver damage in order to evaluate its hepatoprotective effects against hepatotoxicity induced in rats by ethanol at a dosage of 5 g/kg body weight for 60 days.
The degree of liver damage was analysed using serum marker enzyme activities, the total protein, albumin, globulin, ceruloplasmin and liver glycogen contents, and the A/G ratio.
The correlation of serum arylesterase (PON1) activity on phenylacetate determined by an integrated method to classical biochemical indexes of liver damage was investigated for the use of PON1 activity to evaluate liver damage.
The type of hepatic damage revealed by the laboratory tests and the early appearance of the clinical symptoms with non-toxic serum CBZ levels support the hypothesis of an idiosyncratic reaction to CBZ.
It is well known that hepatitis C virus (HCV) can be associated with cryoglobulinemia- induced central and peripheral nervous system disorders, even without significant hepatic damage.
The focal hepatic lesion caused by local injection of absolute alcohol in rats was evaluated with ultrasonic contrast agent and pathologic examination.
It was concluded that ultrasonic contrast agent plus pulse inversion harmonic imaging could be used to assess the size of the focal hepatic lesion caused by local injection of absolute alcohol in rats.