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   慢性丙型病毒性肝炎 的翻译结果: 查询用时:0.012秒
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慢性丙型病毒性肝炎
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  “慢性丙型病毒性肝炎”译为未确定词的双语例句
     METHODS: Fluorescence quantitative RT-PCR was used to detect the quantitation of HCV RNA in PBMC and plasma, and immunohistochemistry assay was applied to identify HCV NS3 protein expression in PBMC from 20 patients with chronic hepatitis C;
     方法:20例慢性丙型病毒性肝炎患者血浆、PBMC中的HCV RNA含量应用荧光定量RT-PCR检测,应用免疫组化技术检测HCV NS3在PBMC中的表达;
短句来源
     The levels of anti-HCV,HCV-RNA and anti-α2b-IFN-IgG in serum of 94 patients with chronic hepatitis C,which was treated with α2b-IFN were respectively detected in different course of treatment.
     选择 94例慢性丙型病毒性肝炎 (慢性丙肝 )患者 ,采用 α2 b-干扰素 ( α2 b- IFN)治疗 ,动态检测其血清抗 - HCV、 HCV- RNA及α2 b- IFN- Ig G表达水平。
短句来源
     Study of HCV genetype distribution to 71 patients with chronic hepatitis C in Shanghai district
     上海地区71例慢性丙型病毒性肝炎患者基因型分布研究
短句来源
     Objective To study the significance of Fas-Fas ligand (FasL)-CPP32 mediated hepatocytic apoptosis and the relationship between their expression and hepatitis C virus (HCV) antigens in pathogenesis of chronic hepatitis C (CHC).
     目的探讨慢性丙型病毒性肝炎(CHC)中Fas-FasL-CPP32介导的细胞凋亡的意义及其与丙型肝炎病毒(HCV)抗原表达间的关系。
短句来源
     Investigation on nosocomial infection in patients with chronic hepatitis C
     慢性丙型病毒性肝炎患者医院感染调查研究
短句来源
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  相似匹配句对
     Clinic Manifestation of Chronic C Virus Hepatitis
     慢性病毒性肝炎的临床表现
短句来源
     Oxymatrine in the Treatment of Chronic Hepatitis C
     氧化苦参碱治疗慢性病毒性肝炎的初步研究
短句来源
     Preliminary Study on Therapeutic Effect of Oxymatrine in Treating Patients with Chronic Hepatitis C
     氧化苦参碱治疗慢性病毒性肝炎的初步研究
短句来源
     THE APPLIED SIGNIFICANCE OF RECOMBINANT IMMUNOBLOT ASSAY IN CHRONIC HEPATITIS C
     RIBA在慢性病毒性肝炎中的应用价值
短句来源
     Investigation on nosocomial infection in patients with chronic hepatitis C
     慢性病毒性肝炎患者医院感染调查研究
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  chronic virus hepatitis c
Preparation Viusid containing glycyrrhyzin acid, possesses clinical efficiency in treatment of chronic virus hepatitis C.
      
Viusid can be applied both in monotherapy and, first of all, in combination with interferons for treatment of chronic virus hepatitis C.
      


Aims: To evaluate Oxymatrine therapy of chronic hepatitis C. Methods: Seventeen patients were administrated Oxymatrine in a dose of 600mg/d intramusculary for 3 months. Results: Oxymatrine was more significantly efffective in treated group than control in disappearance of serum HCV RNA: 8/17 (47.1%) of Oxymatrine treated patients vs 1/18(5.6%) controls received vitatnine products (P<0.05). Serum levels of Ⅳ collagen (Ⅳ-CL) and plasma levels of soluble interleukin-2 receptor (sIL-2R) were both reduced from 233.1...

Aims: To evaluate Oxymatrine therapy of chronic hepatitis C. Methods: Seventeen patients were administrated Oxymatrine in a dose of 600mg/d intramusculary for 3 months. Results: Oxymatrine was more significantly efffective in treated group than control in disappearance of serum HCV RNA: 8/17 (47.1%) of Oxymatrine treated patients vs 1/18(5.6%) controls received vitatnine products (P<0.05). Serum levels of Ⅳ collagen (Ⅳ-CL) and plasma levels of soluble interleukin-2 receptor (sIL-2R) were both reduced from 233.1 ±196.7 (μg/ml) and 4780.2±2917.8(pg/ml) to 139.4±93.3 (μg/ml) and 2639.5±995.8 (pg/ml), respectively, after Oxymatrine treatment for 3 months (P<0.05). Conclusions: Oxymatrine is effective in eliminating HCV RNA and reducing fibrosis activity.

目的:初步探讨氧化苦参碱治疗慢性丙型病毒性肝炎的效果及其机制。方法:43例慢性HCV感染患者随机分为氧化苦参碱治疗组(20例)和一般护肝药物对照组(23例)。治疗组给予氧化苦参碱每日600毫克肌注,疗程三个月。结果:治疗组可统计病例17例,其血清HCV RNA转阴8例(47.1%),转阴率显著高于对照组可统计病例(18例),血清HCV RNA转阴1例(5.6%)(P<0.05)。治疗组第1、2月末血清丙氨酸转氨酶(ALT)复常率均高于对照组(各为P<0.05),但治疗结束时两组复常率间无显著差异。治疗组治疗后血浆可溶性白介素-2受体(sIL-2R)水平和血清Ⅳ型胶原(IV-CL)水平较治疗前显著下降(分别为P<0.01,P<0.05),对照组在研究开始及结束时sIL-2R和Ⅳ-CL水平却无显著差异(均P>0.05)。治疗组血浆sIL-2R水平和血清Ⅳ-CL水平下降值显著高于对照组(分别P<0.01,P<0.05)。治疗组均有注射局部疼痛,但可忍受,1例出现皮肤瘙痒,未见其他不良反应。结论:氧化苦参碱有抑制HCV增殖、抗肝纤维化及调节宿主免疫反应的作用,可能成为治疗慢性HCV感染安全而有效的药物。

Objective: To evaluate the efficacy of oxymatrine in treating chronic hepatitis C and its mechanism. Methods: Forty three patient were divided randomly into the treated group (20 cases) and the control group (23 cases). The treated group was given oxymatrine 600 mg per day intramuscularly, and the control group was given the general liver protective agents such as vitamins. The therapeutic course of both groups was 3 months. Results: HCVRNA of 8 in 17 cases (47 1%) of the treated group converted to negative,...

Objective: To evaluate the efficacy of oxymatrine in treating chronic hepatitis C and its mechanism. Methods: Forty three patient were divided randomly into the treated group (20 cases) and the control group (23 cases). The treated group was given oxymatrine 600 mg per day intramuscularly, and the control group was given the general liver protective agents such as vitamins. The therapeutic course of both groups was 3 months. Results: HCVRNA of 8 in 17 cases (47 1%) of the treated group converted to negative, while in 18 cases of the control group, the negative conversion only took place in 1 patient (5.6%), the negative conversion rate was significantly higher in the treated group than that in the control group (P<0 05). The normalization rates of serum alanine transaminase (ALT) of the treated group after 1 month and 2 months treatment was higher than that of the control group, but after 3 months treatment, the normalization rates of the two groups were not different significantly. Plasma level of soluble interleukin 2 receptor and serum level of collagen type Ⅳ in the treated group were lowered significantly after treatment, but in the control group, there were no significant change, the difference between the two groups was significant (P<0 01,P<0 05). Conclusion: Oxymatrine is effective in inhibiting proliferation of HCV, antagonisting liver fibrosis and regulating immune reaction of the host, so it could be a safe, effective durg in treating chronic hepatitis C.

目的 :初步探讨氧化苦参碱治疗慢性丙型病毒性肝炎的效果及其机制。方法 :43例慢性丙型肝炎病毒(HCV)感染患者随机分为治疗组 (2 0例 )和对照组 (2 3例 )。治疗组给予氧化苦参碱每日 60 0mg肌肉注射 ,对照组给予维生素类一般护肝药物 ,疗程均为 3个月。结果 :治疗组可统计病例 1 7例中血清HCVRNA转阴 8例(47 1 % )、对照组可统计病例 1 8例中血清HCVRNA转阴 1例(5 6% ) ,两组转阴率比较有显著性差异 (P <0 0 5 )。治疗组治疗第 1、2个月末血清丙氨酸转氨酶(ALT)复常率均高于对照组(均为P <0 0 5 ) ,但治疗结束时两组复常率间无显著性差异。治疗组治疗后血浆可溶性白介素 2受体(SIL 2R)水平和血清IV型胶原(IV CL)水平较治疗前显著下降(分别为P <0 0 1、P <0 0 5 ) ,对照组治疗前后SIL 2R和IV CL水平无显著性差异 (均为P >0 0 5 )。治疗组血浆SIL 2R水平和血清IV CL水平下降值显著高于对照组 (分别P <0 0 1 ,P <0 0 5 )。结论 :氧化苦参碱有抑制H...

目的 :初步探讨氧化苦参碱治疗慢性丙型病毒性肝炎的效果及其机制。方法 :43例慢性丙型肝炎病毒(HCV)感染患者随机分为治疗组 (2 0例 )和对照组 (2 3例 )。治疗组给予氧化苦参碱每日 60 0mg肌肉注射 ,对照组给予维生素类一般护肝药物 ,疗程均为 3个月。结果 :治疗组可统计病例 1 7例中血清HCVRNA转阴 8例(47 1 % )、对照组可统计病例 1 8例中血清HCVRNA转阴 1例(5 6% ) ,两组转阴率比较有显著性差异 (P <0 0 5 )。治疗组治疗第 1、2个月末血清丙氨酸转氨酶(ALT)复常率均高于对照组(均为P <0 0 5 ) ,但治疗结束时两组复常率间无显著性差异。治疗组治疗后血浆可溶性白介素 2受体(SIL 2R)水平和血清IV型胶原(IV CL)水平较治疗前显著下降(分别为P <0 0 1、P <0 0 5 ) ,对照组治疗前后SIL 2R和IV CL水平无显著性差异 (均为P >0 0 5 )。治疗组血浆SIL 2R水平和血清IV CL水平下降值显著高于对照组 (分别P <0 0 1 ,P <0 0 5 )。结论 :氧化苦参碱有抑制HCV增殖 ,抗肝纤维化及调节宿主免疫反应的作用 ,可能成为治疗慢性HCV感染安全而有效的药物。

In the clinical comparison and observation of the therapeutic effect in the treatment of chronic hepatitis C in Chinese medicine group by the blood activating and stasis resolving method(15 cases)and in the interferon group(15 cases),the results showed that the negative transferring rate of HCV TNA was 20.00% in both Chinese medicine group and interferon group,the negative transferring rate of anti HCV was respectively 33.33% and 26.66%,the improvement...

In the clinical comparison and observation of the therapeutic effect in the treatment of chronic hepatitis C in Chinese medicine group by the blood activating and stasis resolving method(15 cases)and in the interferon group(15 cases),the results showed that the negative transferring rate of HCV TNA was 20.00% in both Chinese medicine group and interferon group,the negative transferring rate of anti HCV was respectively 33.33% and 26.66%,the improvement of the symptoms and liver functions was obviously better in Chinese medicine group than in the interferon group and that bad reaction in various degrees existed in the interferon group.In comparison with the interferon group,the long term anti virus effect was more stable and persistent statistically in Chinese medicine group.It was proved in the pathological examinations that Chinese medicine could abate edema and congestion of liver cell,infiltration of inflammatory cell in the portal area and necrosis of liver cell.

临床比较观察活血化瘀为主的中药组(15例)与干扰素组(15例)治疗慢性丙型病毒性肝炎的疗效。结果发现中药组与干扰素组对HCVRNA的转阴率均为20.00%,抗HCV的转阴率分别为33.33%和26.66%;在症状、肝功能的改善方面,中药组明显优于干扰素组,干扰素组存在不同程度的不良反应。中药组抗病毒远期疗效与干扰素组比较更为稳定持久,具有统计学意义。病理检测结果证实中药组有改善肝细胞充血水肿、汇管区的炎症细胞浸润和肝细胞坏死的作用。

 
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