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   浸润前沿 的翻译结果: 查询用时:0.008秒
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浸润前沿
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  invasive tumor front
     Results There are significantly difference in the invasive tumor front(ITF) and the center of oral mucosa carcinoma about the WHO(1997) grading(P<0.05).
     结果口腔黏膜癌浸润前沿(ITF)和非前沿WHO(1997)分级差异有显著性(P<0.05);
短句来源
     Expression of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 at the Invasive Tumor Front of Oral Squamous Cell Carcinoma
     口腔鳞癌浸润前沿中基质金属蛋白酶-9及其抑制剂-1的表达
短句来源
     ObjectiveTo detect the expression of MMP-9,TIMP-1 and CD34 in oral squamous cell carcinomas(OSCC) and the invasive tumor front(ITF) of OSCC, to investigate microvessel density(MVD) stained by monoclonal antibody CD34. The correlations between MMP-9,TIMP-1 at ITF and MVD and clinicopathological features were analyzed.
     检测基质金属蛋白酶-9(MMP-9)、基质金属蛋白酶抑制剂-1(TIMP-1)及CD34在口腔鳞状细胞癌及癌浸润前沿的表达、观察分布,并记数CD34标记的肿瘤间质微血管密度,分析三者的关系及在口腔鳞癌侵袭中的意义。
短句来源
     The study of proliferation of cells at the invasive tumor front of squamous cell carcinoma of tongue
     舌鳞状细胞癌浸润前沿细胞增殖的研究
短句来源
     Objective: To study the expression of the epithelial adhesion molecule E cadherin (E-cad) and its associated proteins α catenin ( α-cat) and β catenin (β -cat) of 52 oral squamous cell carcinomas (OSCCs), especially at the invasive tumor front(ITF), as well as correlations with clinicopathological characteristics.
     目的:检测上皮细胞粘附分子E-钙粘素(E-cad)和胞内蛋白α-连环素(α-cat)与β-连环素(β-cat)在口腔鳞状细胞癌及癌浸润前沿的表达,观察分布、分析三者在口腔鳞癌侵袭、转移中的意义。
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  “浸润前沿”译为未确定词的双语例句
     Results The expression of PCNA( P <0.001),Ki67( P <0.001), AgNOR number( P <0.001)at the ITF were higher than those of other parts.
     结果 浸润前沿PCNA、Ki6 7的表达和AgNOR均数均明显高于非前沿部分 ,差异有极显著性 (P <0 .0 0 1) ;
短句来源
     The IFG score was significantly correlated with the expression of PCNA( P <0.05), AgNOR number( P <0.01)at the ITF.
     浸润前沿PCNA标记指数 (P <0 .0 5 )、AgNOR均数 (P <0 .0 1)与浸润前沿分级 (IFG)总分呈正相关关系 ;
短句来源
     The IFG score was significantly correlated with the expression of PCNA(P<0.05).
     浸润前沿PCNA标记指数(LI)(P<0.05)与浸润前沿分级(IFG)总分呈正相关关系。
短句来源
     The expression of MMP-9 in ITF was associated with to the size of tumor (P<0.05), depth of inflicating(P<0.01),MVD(P<0.01), score of IFG(P<0.01)and survival time (P<0. 01) positively.
     3.鳞癌浸润前沿区MMP-9、TIMP-1的表达明显高于非前沿部分,差异有显著性(P<0.001)。
短句来源
     Objective: To investigate the expression of matrix metalloproteinase-9(MMP-9) and tissue inhibitor of metalloproteinase-1(TIMP-1) and to explore its significance in oral squamous cell carcinoma (OSSC).
     目的:检测基质金属蛋白酶9(MMP9)及其抑制剂1(TIMP1)在口腔鳞状细胞癌及浸润前沿中的表达并探讨其意义。
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  相似匹配句对
     Progress in Science
     科学前沿
短句来源
     FRONTIER IN SCIENCE
     科学的前沿
短句来源
     The Study of Proliferation of Cells at the Invasive Tumor Front of Oral Mucosa Carcinoma
     口腔黏膜癌浸润前沿细胞增殖的研究
短句来源
     The study of proliferation of cells at the invasive tumor front of squamous cell carcinoma of tongue
     舌鳞状细胞癌浸润前沿细胞增殖的研究
短句来源
     leucocyte soakage;
     间质白细胞浸润
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Objective To investigate the relationship between microvessel density (MVD), clinical prognosisand CTenhancementofthe peripherallung cancer- Methods 127 casesofperipherallungcancer were examined with CT (87 cases retrospectively and 40 cases prospectively), and MVD were measured with immunohistochemical method byfactor Ⅷonthespecimensoftheresectedtumors- Theresults were analyzed and compared with CTenhancement, metastasis and prognosis-Results The MVD was higher in the peripheral junction zoneandinterstitialareasthan...

Objective To investigate the relationship between microvessel density (MVD), clinical prognosisand CTenhancementofthe peripherallung cancer- Methods 127 casesofperipherallungcancer were examined with CT (87 cases retrospectively and 40 cases prospectively), and MVD were measured with immunohistochemical method byfactor Ⅷonthespecimensoftheresectedtumors- Theresults were analyzed and compared with CTenhancement, metastasis and prognosis-Results The MVD was higher in the peripheral junction zoneandinterstitialareasthan thatinthe parenchymal areas and necrotic zones ofthetumors- Patients with nodal metastasis had higher MVDthanthose withoutnodal metastasis(56-9 ±18-1 versus43-8 ±23-6,P< 0-01)-Those patients who died or had remote metastasis also had higher MVDthanthe survived patients without remote metastasis(56-8±24-4 and 57-6±18-9 versus46-4±22-3,P<0-05)-Both theretrospective group and prospective group,showed much higher microvesseldensityin adenocarcinomathaninthesquamousones(57-6± 18-4 versus41-5 ±20-1 and 61-4 ±9-9 versus 45-1 ±11-2) with significant difference( P< 0-05) ;andthe worsethe degreeoftumordifferentiation,the higherthe microvesselcount- The MVDoftumors with enhancement higherthan 30 HU(69 cases) was significantly higherthan those (18 cases)with enhancementlessthan 30 HU (57-1±22-7 vs42-7±18-4 ,P<0-01) intheretrospectivegroup- In prospectivestudy,the mean enhancement valuein 40 patients was50-6±19-6 HU,andthe peak value appeared atabout1 minute after administration of contrast agent- The mean enhancement value of adenocarcinomas was 53-4 ±23-2 HU (maximum 83 HU, minimum 18 HU) ,higherthan thatin squamous cellcarcinomas (mean value 47-2 ±14-6,maximum 72 HU, minimum 13 HU) but without significant difference ( P> 0-05); but the enhancement ofthe lung cancer correlated well with MVD(r= 0-887 4)- Conclusions Measurement ofthe microvessel density oftumor can determinethe degree of angiogenesis of neoplasm and predict the metastasis or prognosis ofthe lung cancer- Angiogenesis notonlyconstitutesthebasisofenhancementofthetumor,butalsodeterminethevariousdegreesand patterns ofenhancement- Spiraldynamic CTisthetechniqueidealtodemonstratethe enhancementfeatures,which mightbe helpfulin making differentialdiagnosisofpulmonary nodules-

目的 探讨周围型肺癌微血管密度(MVD) 与肿瘤预后以及CT增强程度的相关性。方法 利用免疫组织化学方法测定了127 例周围型肺癌的MVD,并与CT增强程度(87 例回顾性,40 例前瞻性动态增强) 以及转移、预后情况进行对照分析。结果 瘤内微血管的分布以肿瘤外围浸润前沿及间质中较为密集,肿瘤实质区及坏死区血管稀疏。回顾组与前瞻组腺癌的MVD 均明显高于鳞癌,回顾组分别为57-6 ±18-4 与41-5 ±20-1(t=2-745,P<0-01);前瞻组分别为61-4 ±9-9 与45-1 ±11-2(t=2-385,P< 0-05) ,而且分化差的高于分化好的。从淋巴结转移及随访情况看,MVD高与淋巴结转移、远处转移及3 年存活率低关系密切。肺癌相对CT值的变化与微血管密度呈正相关,回顾组肿块增强≥30 HU及< 30 HU的MVD分别为57-1±22-7(69 例) 及42-7 ±18-4(18 例),差异有显著性意义(t=2-669 ,P< 0-01) 。前瞻组40 例肺癌平均增强50-6±19-6 HU,增强高峰在注射对比剂后1 分钟左右,MVD与CT增强的相关系数为0-887 4,P<0...

目的 探讨周围型肺癌微血管密度(MVD) 与肿瘤预后以及CT增强程度的相关性。方法 利用免疫组织化学方法测定了127 例周围型肺癌的MVD,并与CT增强程度(87 例回顾性,40 例前瞻性动态增强) 以及转移、预后情况进行对照分析。结果 瘤内微血管的分布以肿瘤外围浸润前沿及间质中较为密集,肿瘤实质区及坏死区血管稀疏。回顾组与前瞻组腺癌的MVD 均明显高于鳞癌,回顾组分别为57-6 ±18-4 与41-5 ±20-1(t=2-745,P<0-01);前瞻组分别为61-4 ±9-9 与45-1 ±11-2(t=2-385,P< 0-05) ,而且分化差的高于分化好的。从淋巴结转移及随访情况看,MVD高与淋巴结转移、远处转移及3 年存活率低关系密切。肺癌相对CT值的变化与微血管密度呈正相关,回顾组肿块增强≥30 HU及< 30 HU的MVD分别为57-1±22-7(69 例) 及42-7 ±18-4(18 例),差异有显著性意义(t=2-669 ,P< 0-01) 。前瞻组40 例肺癌平均增强50-6±19-6 HU,增强高峰在注射对比剂后1 分钟左右,MVD与CT增强的相关系数为0-887 4,P<0-001 。虽然腺癌的增强幅度高于鳞癌(?

Proliferating cell nuclear antigens(PCNA) in 53 cases of gattric adenocarcionma and 55 cases of colorectal adenocarcinoma in paraffin embedded tissues were detected immunohistochemically, and corelated PCNA grades with clinicopathological features. PCNA peitive cells were located in lower 1/3 zone in normal gastric and colorectal mu cosas, while in most samples of paracancerous mucosas, PCNA positive cells were found even in the upper 1/3 zone and abnormally PCNA grades were higher. In carcinomas, PCNA positive...

Proliferating cell nuclear antigens(PCNA) in 53 cases of gattric adenocarcionma and 55 cases of colorectal adenocarcinoma in paraffin embedded tissues were detected immunohistochemically, and corelated PCNA grades with clinicopathological features. PCNA peitive cells were located in lower 1/3 zone in normal gastric and colorectal mu cosas, while in most samples of paracancerous mucosas, PCNA positive cells were found even in the upper 1/3 zone and abnormally PCNA grades were higher. In carcinomas, PCNA positive cells scattered in the tissues, but stronger in the infiltrating margins. And high PCNA grades related to the infiltrating depth of gastric cancer(P<0.05). It is suggested that the detection of PCNA by immunohistochemistry is a simple method of determining tumor cell proliferat ing activity, and may be useful in evaluating tumor progression.

应用免疫组化方法检测了53例胃癌及55例大肠癌增殖细胞核抗原(PCNA)的表达,并探讨了PCNA分级与临床病理因素间的关系。结果显示正常肠腺体PCNA阳性细胞限于粘膜的下1/3区,在癌旁移行粘膜,PCNA阳性细胞数量增多,且阳性细胞带上移。而胃肠腺癌中PCNA阳性细胞分布呈异质性,在肿瘤浸润前沿一般都较强。PCNA表达与胃癌的浸润范围有关,PCNA分级高者,侵及浆膜及浆膜外的比例明显高于PCNA分级低者(P<0.05),在大肠癌中也显示类似趋势,但P>0.05。表明免疫组织化学方法检测PCNA是一种较简便的检测肿瘤细胞增殖活性的方法,其结果可能有助于临床对肿瘤进展的判断。

Objective To study the immunohistochemical alteration of basement membrane (BM) typeⅣ col lagen and laminin in oral verrucous carcinoma and its BM ultrastructural variati ons Methods 16 cases of oral verrucous carcinoma (OVC), 10 cases of oral squamous cell carcinoma (OSCC) and 9 cases of oral mild to severe epithelial dysplasia (OMSD) were studied by using a immunohistochemical S-P me thod, and the results were analyzed by quantitative method 3 cases of OVC were observed by TEM Results The BM in OVC was...

Objective To study the immunohistochemical alteration of basement membrane (BM) typeⅣ col lagen and laminin in oral verrucous carcinoma and its BM ultrastructural variati ons Methods 16 cases of oral verrucous carcinoma (OVC), 10 cases of oral squamous cell carcinoma (OSCC) and 9 cases of oral mild to severe epithelial dysplasia (OMSD) were studied by using a immunohistochemical S-P me thod, and the results were analyzed by quantitative method 3 cases of OVC were observed by TEM Results The BM in OVC was thicker than in OS CC and OMSD TEM found the basal lamina in some areas showed a marked reduplica tion The BM in OVC was generally intact (13/16), whereas in OSCC it was mostly discontinuous (9/10), especially around the neoplasm front or the small cord co nsisted of a few cells, and mostly continuous in OMSD (6/9) There was a stroma l inflammatory infiltration around tumor nests for all the oral lesions, but it was much heavier in OVC than that in OSCC and OMSD( P<005) There was a positive correlation between intraepithelial lymphocytic infiltration and the BM continuity for OVC( P<001) Conclusions The more c o ntinuous BM and the heavier inflammatory infiltration in the connective tissue o f OVC may be related to its biological behavior

目的 研究口腔粘膜疣状癌基膜Ⅳ型胶原与层粘连蛋白的表达、分布和超微结构改变。方法 采用免疫组化S P法 ,分别检测 16例疣状癌、10例鳞癌和 9例中至重度不典型增生病例中Ⅳ型胶原与层粘连蛋白的表达 ,对表达结果作定量分析 ,并对 3例疣状癌作电镜观察。结果 疣状癌基膜大多数较厚且保持完整 (13/ 16 ) ,电镜下观察基板在一些区域明显增厚。但炎症细胞较多的病例 ,基膜出现中断 (3/ 16 )。鳞癌和中至重度不典型增生基膜相对较薄 ,鳞癌基膜绝大多数不连续 (9/ 10 ) ,尤其在浸润的前沿或小条索状癌结构中 ,基膜基本中断或消失。中至重度不典型增生基膜大多数连续 (6 / 9)。所有病例的癌巢周围间质中都可见炎症细胞浸润 ,疣状癌较鳞癌和中至重度不典型增生中浸润的淋巴细胞更为密集 (P <0 0 5 )。在疣状癌中 ,上皮内炎症细胞浸润与其基膜完整呈正相关关系 (P <0 0 1)。结论 疣状癌基膜较厚 ,较完整且结缔组织中有大量以淋巴细胞为主的炎症细胞浸润 ,可能与其生物学行为有关

 
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