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实验性咳嗽
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  相似匹配句对
     WHY DOES HE COUGH
     莫名其妙的咳嗽
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     the practice is experiment;
     实践的实验性;
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     Cough counter
     咳嗽计数器
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     Reconstruction of the Collateral Circulation in the Experimental Fraction
     实验性骨折愈合的血运重建
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Objective:This paper was to investigate the antitussive action of Dextromethorphan Hydrobromide on trial cough in animals. Methods: We used chemicals and electric stimulation to induce cough. Results: 10 mg/kg and 20 mg/kg of Dextromethorphan Hydrobromide i.g. could effectively decrease the times of cough in mice induced by ammonia water and prolong the latent period. 5.5 mg/kg and 11 mg/kg of Dextromethorphan Hydrobromide i.g. exerted obvious antitussive action on the cough in guinea pigs induced by acrylaldehyde....

Objective:This paper was to investigate the antitussive action of Dextromethorphan Hydrobromide on trial cough in animals. Methods: We used chemicals and electric stimulation to induce cough. Results: 10 mg/kg and 20 mg/kg of Dextromethorphan Hydrobromide i.g. could effectively decrease the times of cough in mice induced by ammonia water and prolong the latent period. 5.5 mg/kg and 11 mg/kg of Dextromethorphan Hydrobromide i.g. exerted obvious antitussive action on the cough in guinea pigs induced by acrylaldehyde. 3.2 mg/kg and 6.4 mg/kg of Dextromethorphan Hydrobromide i.p. also showed obvious antitussive action on the cough in guinea pigs induced by electric stimulation. The reduced rate of coughing times was more than 50% and the inhibitory rate for ammonia water induced cough in mice and acrylaldehyde induced in guinea pigs was 63.94% and 59.02% respectively. Conclusions:Dextromethorphan Hydrobromide exerted obvious antitussive action on the cough induced by various trials.

目的:研究氢溴酸右美沙芬对实验性咳嗽的镇咳作用。方法:化学品引咳法,电刺激引咳法。结果:氢溴酸右美沙芬10mg/kg和20mg/kg给小白鼠灌胃能有效地抑制氨水所致小鼠咳嗽的次数和延长潜伏期;5.5mg/kg和11mg/kg给豚鼠灌胃给药对丙烯醛所致咳嗽有明显镇咳作用;3.2mg/kg和6.4mg/kg给豚鼠腹腔注射,对电刺激引起的咳嗽有明显镇咳作用。咳嗽次数减少率大于50%,抑制率分别为59.02%和63.94%。结论:氢溴酸右美沙芬对多种实验方法引起的咳嗽有明显的镇咳作用。

The pharmcological action of Rubus suavissimus from Guangxi was studied by animal experiment. The results showed that the extract of Rubus suavissimus from Guangxi (GXRE) had cough relieve action on experimental cough in mice caused by dense ammonia water, and could significantly increase outage of phenlored in breathe path, inhibit ear swelling of mice in duced by xylene, decrease body twisting times of mice induced by acetic acid and inhibit spontanous activity. The acute toxicity test of GXRE showed that...

The pharmcological action of Rubus suavissimus from Guangxi was studied by animal experiment. The results showed that the extract of Rubus suavissimus from Guangxi (GXRE) had cough relieve action on experimental cough in mice caused by dense ammonia water, and could significantly increase outage of phenlored in breathe path, inhibit ear swelling of mice in duced by xylene, decrease body twisting times of mice induced by acetic acid and inhibit spontanous activity. The acute toxicity test of GXRE showed that its maximum tolerance is 199.8 g/kg. All these suggests that GXRE have actions of relieving a cough, reducing phelm, anti-inflammation, analgesia and sedation.

:动物实验研究了广西甜茶的药理作用。结果发现 :广西甜茶提取物对小鼠浓氨水实验性咳嗽有止咳作用 ;能明显增加小鼠呼吸道酚红排出量 ;抑制小鼠二甲苯所致耳肿 ;可减少醋酸所致扭体次数和抑制自发活动 ;广西甜茶提取物的急性毒性试验表明 ,其最大耐受量为 199.8g生药 /kg。提示广西甜茶具止咳祛痰、抗炎、止痛和镇静作用。

Objective:To study the mechanisms and curative effects of Anti -Pneumonia Instant Powder.Methods:245Infants with bronchial pneumo-nia were divided randomly into 2grou ps,experimental group(165cases)and controlled group(80cases).Both of which Sodium Cefotaxime were injected intravenously.And the exp erimental group received the Anti -Pneumonia Instant Powder while the c ontrolled group received Acute Bronchitis Mixture.Thereafter,ex ternal and internal antibacterial t ests were performmed.Also such effects w...

Objective:To study the mechanisms and curative effects of Anti -Pneumonia Instant Powder.Methods:245Infants with bronchial pneumo-nia were divided randomly into 2grou ps,experimental group(165cases)and controlled group(80cases).Both of which Sodium Cefotaxime were injected intravenously.And the exp erimental group received the Anti -Pneumonia Instant Powder while the c ontrolled group received Acute Bronchitis Mixture.Thereafter,ex ternal and internal antibacterial t ests were performmed.Also such effects w ere observed as triple vaccines on fevered rabbits,10%ammonia water o n the experimental cough of rats and10%egg white on swelling degree of ra ts' plantar region.In the meantime,long -term toxicity tests were perfo rmmed and maximum tolerance limit wes measured.Results:S uch effects obtained from the experimental group as reducing fever,relieving cough a nd asthma,vanishing time of moist rales and clinical curative effect were prior to that of the controlled group(P<0.005).External and internal antibacterial tests suggested that the mixture had wide antibacterial effe ct and no side effects and poisoning reaction.A notable treatment effec t has achieved in reducing temperatu res of the fevered rabbits induced by triple vaccines and in relieving experi-mental cough of rats as well as in redu cing the swelling of the plantar region of rats induced by egg white.L ong -term toxicity tests have not got obvious poisoning reaction and accu mulative reaction and the LD50 of the rats is 80g /kg·d.Conclusions:Anti -Pneumonia mixture functions i n relieving the symptoms and improvin g the physical signs of infant pneu-monia,reaching a good clinical trea tment.

目的探讨肺炎冲剂治疗小儿支气管肺炎的疗效及机理。方法将245例支气管肺炎患儿随机分为观察组(165例)和对照组(80例),两组均予头孢噻肟钠静点,观察组口服肺炎冲剂,对照组口服急支糖浆;用试管法作体外抗菌试验,用孙氏综合法作体内抗菌实验,观察(1)三联疫苗对致热兔体温的影响,(2)10%氨水对小鼠实验性咳嗽的影响,(3)10%蛋清液对大鼠足跖肿胀度的影响,并作长期毒性试验和最大耐受量测定。结果退热、止咳、平喘、湿罗音消失时间及临床疗效,观察组均优于对照组(P<0.005);体外抗菌试验对金黄色葡萄球菌、肺炎球菌、肺炎克雷伯杆菌、流感嗜血杆菌、溶血性链球菌、绿脓杆菌的MIC依次为1.0950、1.0950、1.4600、1.0950、0.3650及0.3650g/ml,MBC依次为1.460、未测出、未测出、1.4600、1.0950及0.7300g/ml;体内抗菌实验对肺炎球菌、肺炎克雷伯杆菌感染小鼠的ED50测定分别为3.3306和3.5768g生药/kg体重,95%可信限分别为2.2718~4.0752和2.2999~4.2648g生药/kg体重;对三联疫苗致兔体温升高有显著降温作用;对小鼠#...

目的探讨肺炎冲剂治疗小儿支气管肺炎的疗效及机理。方法将245例支气管肺炎患儿随机分为观察组(165例)和对照组(80例),两组均予头孢噻肟钠静点,观察组口服肺炎冲剂,对照组口服急支糖浆;用试管法作体外抗菌试验,用孙氏综合法作体内抗菌实验,观察(1)三联疫苗对致热兔体温的影响,(2)10%氨水对小鼠实验性咳嗽的影响,(3)10%蛋清液对大鼠足跖肿胀度的影响,并作长期毒性试验和最大耐受量测定。结果退热、止咳、平喘、湿罗音消失时间及临床疗效,观察组均优于对照组(P<0.005);体外抗菌试验对金黄色葡萄球菌、肺炎球菌、肺炎克雷伯杆菌、流感嗜血杆菌、溶血性链球菌、绿脓杆菌的MIC依次为1.0950、1.0950、1.4600、1.0950、0.3650及0.3650g/ml,MBC依次为1.460、未测出、未测出、1.4600、1.0950及0.7300g/ml;体内抗菌实验对肺炎球菌、肺炎克雷伯杆菌感染小鼠的ED50测定分别为3.3306和3.5768g生药/kg体重,95%可信限分别为2.2718~4.0752和2.2999~4.2648g生药/kg体重;对三联疫苗致兔体温升高有显著降温作用;对小鼠实验性咳嗽有显著的镇咳作用;对大鼠蛋清型足跖肿胀有显著的抗炎作用;长期毒性试验未见明显药物毒性反应及药物蓄积性反应发生;小鼠LD50为80g/kg·d。结论肺炎冲剂可明显改善小儿肺炎的体征和症状,有显著的

 
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