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慢性乙肝病毒性肝病
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  chronic hbv hepatic disease
     Detection of HBV-DNA in serum and PBMC of the patients with chronic HBV hepatic disease by
     应用PCR技术检测慢性乙肝病毒性肝病血清及外周血单个核细胞中HBV-DNA
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  patients with chronic hbv hepatic disease
     Detection of HBV-DNA in serum and PBMC of the patients with chronic HBV hepatic disease by
     应用PCR技术检测慢性乙肝病毒性肝病血清及外周血单个核细胞中HBV-DNA
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  “慢性乙肝病毒性肝病”译为未确定词的双语例句
     Results:12 of 63 (19.1%) were only one kind of autoimmune antibody in sera of patients with hepatitis B and 12 of 40(30%) of patients with hepatitis C.
     结果 :6 3例慢性乙肝病毒性肝病组检出一种以上自身抗体者 1 2例 ( 1 9 1 % ) ;
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  相似匹配句对
     Relationship between chronic viral hepatopathy and gastroduodenal mucosal lesions
     慢性病毒性肝病时胃十二指肠病变的研究
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     Variation of fibronectin and its significance in chronic virus hepatitis
     纤维连接蛋白在慢性病毒性肝病中的变化及其意义
短句来源
     HBV replication as a cause of reactivity of Chronic liver diseases
     乙肝病毒复制是慢性肝病活动的直接原因
短句来源
     Detection of HBV-DNA in serum and PBMC of the patients with chronic HBV hepatic disease by
     应用PCR技术检测慢性乙肝病毒性肝病血清及外周血单个核细胞中HBV-DNA
短句来源
     Study of the relationship between chronic viral hepatopathy (CVH) and gastroduodeual mueosal lesions (GDML) and the mechanism of GDML in CVH patients
     慢性病毒性肝病与胃十二指肠粘膜病变相互关系的研究
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HBV-DNA in the serum and peripheral blood mononucleated

本文应用多聚酶连反应(PCR)技术检测了104例慢性乙肝病毒性肝病患者血清及外周血单个核细胞(PBMC)中HBV-PNA,并与放免法进行了比较。结果显示,PCR检测结果更能客观地反应HBV在体内存在的状态,在外周血单个核细胞中有HBV感染;104例慢性肝病患者外周血单个核细胞中HBV-DNA的检出率为28.8%,而血清中HBV-DNA阴性的20例患者有7例PBMC中检测出HBV-DNA,占35%。因此,在检测血清HBV标志物及HBV-DNA的同时检测PBMC中的HBV-DNA可进一步防止HBV传播与输血后肝炎的发生。

Objective:To study on reasonable use and effect in treating chronic viral hepatic disease with Sinogen.Methods:21 patients with HBV DNA、HBeAg positive chronic viral disease,7 carrier with HBV DNA、HBeAg and 8 patients with HCV RNA positive hepatitic C were treated with Sinogen 3 U per day for 15~30 d and then 3 U every other day for 6 months.Results:HBV DNA positive turned into negative rates in 3 months and 6 months after treatment were 33.3%、47.6% in chronic HBV hepatic disease group respectively,28.6%、42...

Objective:To study on reasonable use and effect in treating chronic viral hepatic disease with Sinogen.Methods:21 patients with HBV DNA、HBeAg positive chronic viral disease,7 carrier with HBV DNA、HBeAg and 8 patients with HCV RNA positive hepatitic C were treated with Sinogen 3 U per day for 15~30 d and then 3 U every other day for 6 months.Results:HBV DNA positive turned into negative rates in 3 months and 6 months after treatment were 33.3%、47.6% in chronic HBV hepatic disease group respectively,28.6%、42 9% in carrier group and HCV RNA turned into negative rates in 3 months and 6 months after treatment were 12.5%,25.0% in chronic hepatitic C respectively and higher than those of control groups.ALT and AST activities in patients treated with Sinogen group were returned to nomal levels faster than those of control groups ( P <0.01).Conclusion:There was relationship between HBeAg、HBV DNA turned into negative rates and treatment course,and effect to treat chronic viral hepatic disease with Sinogen.

目的:为了研究赛若金(干扰素)在慢性病毒性肝病治疗中的合理应用及赛若金对慢性病毒性肝病的疗效比较。方法:对21例HBVDNA、HBeAg阳性的慢性乙型病毒性肝病患者,7例HBVDNA、HBeAg阳性无症状携带者及8例HCVRNA阳性慢性丙型肝炎患者应用赛若金3~6U,每日1次肌注,15~30d后隔日1次肌注,治疗3~6个月。结果:21例慢性乙肝病毒性肝病患者疗程HBVDNA阴转率3个月时为333%,6个月时为476%;HBeAg阴转率3个月时为381%,6个月时为571%。7例乙肝病毒携带者HBVDNA阴转率3个月时为286%,6个月时为429%。8例慢性丙肝患者HCVRNA阴转率3个月时为125%,6个月时为250%,明显高于常规治疗组(P<001)。应用赛若金治疗组大多数患者ALT与AST水平恢复较快。结论:赛若金抑制病毒作用与疗程密切相关,抗病毒治疗疗效肯定。

Objective:To analyse clinical signification of four kinds of autoimmune antibodies in the patients with viral hepatitis.Methods:ANA RF,anti TM and dsDNA Ab in sera of patients with viral hepatitic disease were detected by means of indirect immune fluerscence(IIF) and ELISA.Results:12 of 63 (19.1%) were only one kind of autoimmune antibody in sera of patients with hepatitis B and 12 of 40(30%) of patients with hepatitis C.There were significantly higher than those of alcoholic and drug hepatitis group(P<0...

Objective:To analyse clinical signification of four kinds of autoimmune antibodies in the patients with viral hepatitis.Methods:ANA RF,anti TM and dsDNA Ab in sera of patients with viral hepatitic disease were detected by means of indirect immune fluerscence(IIF) and ELISA.Results:12 of 63 (19.1%) were only one kind of autoimmune antibody in sera of patients with hepatitis B and 12 of 40(30%) of patients with hepatitis C.There were significantly higher than those of alcoholic and drug hepatitis group(P<0 01).Conclusion:autoimmune reaction was participated in the couse of viral hepatic disease development and there was some clinical significant in detecting autoimmune antibodies in sera of patients with viral hepatitic.

目的 :探讨慢性肝病患者自身免疫状况及其临床意义。方法 :应用ELISA法与间接免疫荧光法检测不同类型肝病患者血清中类风湿因子 (RF) ,抗核抗体 (ANA)、抗甲状腺微粒体抗体 (Anti TM)、抗双链DNA抗体 (dsDNA Ab) 4种自身抗体。结果 :6 3例慢性乙肝病毒性肝病组检出一种以上自身抗体者 1 2例 ( 1 9 1 % ) ;40例丙肝病毒性肝病组检出一种以上自身抗体者 1 2例 ( 30 % ) ,明显高于对照组酒精、药物性肝炎组 5 7% ,3 3% (P <0 0 1 )。结论 :自身免疫反应参与慢性肝病的发生发展过程 ,慢性肝病患者自身抗体测定 ,对于指导临床治疗具有一定意义。

 
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