Take the ratio of radioactivityiv urine to that in feces as 1,an equation of excretion and an equation of retention were fitted by theleast-square method and the initial body burden of ~(106)Ru for these six worders was estimated with theseequations.
While the retention equation of ~(147)Pm is: R(t)=0.199e~(-.1452t)+0 .812e~(0.0008t) Where the fast component T_1was 4.77 d: and the slow com-poment T_2 was 866.3 d.
The retention equation of ~(134)C_S was well described. by a two-exponential function, that is=R(t)=18.04~(-9.3175t)+ 45.13 e~(-0.0423t) There are tworetention components, fast and slow. The effective biological T_(1/2) were 0.07 and16.14 days respectively.
The fast component is Tt = 4. 77 d and the slow component is T2 = 866. 3 d. For the 134Cs, the equation is R(t) = 18. 04e-9.3175t + 45. 13e-0.0423t. The fast component is T1 = 0. 07 d and the slow component is T2 = 16.14 d.
The retention process of (147)pm in the whole body was fitted by an equation with least square method as follow; R(t) = 0.199e-(0.1452t)+0.812e(-00008t) which consists of two components: the fast component T1=4.77d and the slow component T2=866.3d.
In the absence of IIR the present retention equation reduces, as expected, to the relationship that describes the influence of organic modifier on retention behaviour in reversed-phase liquid chromatography.
The purpose of this study is to ascertain the correlation between the retentive peculiarity of '''Pm and its possible mutagenic effect in organism administered once or for consecutive 5 days.After 147Pm was given iv for once to male rats, it was selectively localized in liver in early stage. 5 days later, 147Pm was located in skeleton predominantly. It caused marked chromosome aberrations on bone marrow cells. There was positive relationship between chromosome aberration rates and the amount of 147Pm admini...
The purpose of this study is to ascertain the correlation between the retentive peculiarity of 147Pm and its possible mutagenic effect in organism administered once or for consecutive 5 days. After 147Pm was given iv for once to male rats, it was selectively localized in liver in early stage. 5 days later, 147Pm was located in skeleton predominantly. It caused marked chromosome aberrations on bone marrow cells. There was positive relationship betwen chromosome aberration rates and the amount of 147Pm admini...