Conclusions: Brachytherapy by implantation of Iodine-125 seeds of remained tumor tissues in patient with later malignant tumor has a satisfactory outcome in short term. It can be a therapy of malignant tumors.
Methods Thirty-seven patients with T3 or T4 unresectable esophageal cancer were allocated into two groups. The patients of group A were implanted a covered self-expandable metal stent and of group B were implanted a self-expandable metal stent and Iodine-125 seeds.
It can produced domesticlly. It has been reported that interstitial implantation of radioactive iodine-125 seeds has made significant efficacy in the treatment of malignant tumors such as prostate carcinoma.
The ratio of developing was 8.7%. Couclusion:The curative effect of malignant tumours of advanced stage treated by Shenmai injection combined with implantation of radioiodine-125 particle was obvious on improving the quality of life and controlling the grouth of tumours.
1-125 seeds which were made in China recently has the characteristic of low dose rate and persistent irradiation, which can redeem the insufficiency of the irradiation and be the permanent radiation source.
Combined Fractionated External Beam Radiotherapy and Low-Dose-Rate Iodine-125 Seeds in an Experimental Tumor System
For brachytherapy, iodine- 125 seeds were implanted to deliver a homogeneous dose of 40 cGy/hr for a maximum of 6000 cGy to the enhancing tumor margin.
Additionally,l-[methyl-11C]-methionine uptake was measured in five subjects before and 1 year after computerized tomography (CT)-guided stereotactic and computer-assisted implantation of iodine-125 seeds.
An incidence of 40% (8/20 patients) was found after permanent implantation of Iodine-125 seeds.
Interstitial irradiation of a large, low grade ependymoma with stereotactically implanted Iodine-125 seeds
I-125 seeds were permanently implanted into 25 parasellar-clival meningiomas (median age of patients, 56 y) and 19 globoid meningiomas in the elderly (median age of patients, 77 y) using stereotactic technique and 3-D dose planning.
Preliminary study of correction of original metal artifacts due to I-125 seeds in postimplant dosimetry for prostate permanent i