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神经退变和再生
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  “神经退变和再生”译为未确定词的双语例句
     Results There were no obvious changes on T1WI on crushed side. On the images of the other four sequences, the SIR increased after 1 week of being crushed, reached the maximum at 2 weeks, decreased at 4 weeks, and obviously decreased on 8 weeks, which correlated well with the degeneration and regeneration of the nerve and limb function recovery.
     结果 神经挤压伤后,除T1WI上无明显改变,在其余四序列上SIR均不同程度升高,1周时神经远段SIR升高,2周时SIR达高峰,4周时开始下降,8 周时下降较明显,与损伤后神经退变和再生及肢体功能的动态变化相一致。
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     (4)Acceleration of nerve regeneration.
     ( 4 )加速神经再生
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     Objective:To investigate myoglobin and actin expression of skelectal muscle after denervation.
     目的:探讨骨骼肌失神经后的退变再生
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     ARCHITECTURAL CHANGES OF DEGENERATING AND REGENERATING NERVES
     神经退变再生的构筑变化
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     The Role of Astrocytes in Neurogenesis
     星形细胞在神经再生中的作用
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     The Degeneration and Regeneration of Skeletal Muscle After Tenotomy
     肌腱切断后骨骼肌的退变再生
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  nerve degeneration and regeneration
These observations strongly suggest the involvement of apoptosis in peripheral nerve degeneration and regeneration.
      
In conclusion, during peripheral nerve degeneration and regeneration, supernumerary Schwann cells are removed by apoptosis, however, it lacks most of the nuclear events of usual apoptosis.
      
Identify the signs and symptoms of peripheral nerve degeneration and regeneration and how these changes can be detected by electro-diagnostic testing.
      
Montine, Interactions between apolipoprotein E E during nerve degeneration and regeneration, Proc.
      


Objective To study the degeneration and regeneration of skeletal muscle after denervation.Methods Denervation was carried out in gastrocnemius muscles in 30 adult BALB/C mice by cutting the sciatic nerve. The gastrocnemius muscles were removed at 1,2,4,8,12,16 weeks after denervation, respectively. Specimens were processed for histological study and immunohistochemical technique.Results Muscle fiber atrophy followed by degerneration and regeneration was observed in the early period of denervation. Fusion of...

Objective To study the degeneration and regeneration of skeletal muscle after denervation.Methods Denervation was carried out in gastrocnemius muscles in 30 adult BALB/C mice by cutting the sciatic nerve. The gastrocnemius muscles were removed at 1,2,4,8,12,16 weeks after denervation, respectively. Specimens were processed for histological study and immunohistochemical technique.Results Muscle fiber atrophy followed by degerneration and regeneration was observed in the early period of denervation. Fusion of the regenerated muscle cells with each other followed by degeneration of the cells and growth of fibroconnective tissue were observed in the later stage. The expression of myoglobin and actin decreased in 1~4 weeks after denervation. The postive expression of the proteins was observed in some 8 weeks′ cells and in many degenerated 12~14 weeks′ muscle cells.Conclusion Degeneration and regeneration may coexisted in the denervated muscles. The regenerated muscle cells can′t fully develop due to the deficit of nerve regulation and degenerate again. The regenerated muscle cells will melt each other and can′t develop to mature muscle fiber in the later stage.

目的 探讨骨骼肌失神经的退变和再生。方法 以纯系BALB C小白鼠为实验动物 ,切断一侧坐骨神经 ,术后 1,2 ,4 ,8,12 ,16周分别处死动物 ,取腓肠肌分别进行光电镜观察和免疫组化研究。结果 骨骼肌失神经早期主要为肌纤维萎缩 ,随后退变和再生 ,较长时间失神经后再生的肌细胞再发生退变。失神经后 1~ 4周肌动蛋白和肌红蛋白表达均降低 ,8周出现较小的细胞阳性染色 ,肌纤维阳性染色主要位于核周 ,12~ 16周大片的细胞核周有较浅的阳性胞浆染色。这些细胞不具正常肌纤维形态。结论 骨骼肌失神经后退变和再生同时存在 ,由于无神经支配 ,再生的肌细胞不能分化发育为成熟的肌纤维 ,而再发生退变 ;较长时间失神经后再生的成肌细胞相互融合呈片状分布 ,未能发育为成熟的肌纤维。

Objective To evaluate MR imaging signal intensity ratio (SIR) in different severities of crushed sciatic nerve in rabbits. Methods Thirty-two adult New Zealand white rabbits were divided into two groups randomly, and animal models of acute crushed sciatic nerve were established. Right hind limbs were as control sides. MR imaging of bilateral sciatic nerves were performed at 1, 2, 4, and 8 weeks after the crush injury and SIR was then measured, respectively. Results There were no obvious changes on T1WI on...

Objective To evaluate MR imaging signal intensity ratio (SIR) in different severities of crushed sciatic nerve in rabbits. Methods Thirty-two adult New Zealand white rabbits were divided into two groups randomly, and animal models of acute crushed sciatic nerve were established. Right hind limbs were as control sides. MR imaging of bilateral sciatic nerves were performed at 1, 2, 4, and 8 weeks after the crush injury and SIR was then measured, respectively. Results There were no obvious changes on T1WI on crushed side. On the images of the other four sequences, the SIR increased after 1 week of being crushed, reached the maximum at 2 weeks, decreased at 4 weeks, and obviously decreased on 8 weeks, which correlated well with the degeneration and regeneration of the nerve and limb function recovery. There was obvious statistic difference between distal segment SIR of the control group and that of the injured group (P<0.001). Conclusion MR imaging SIR can be used to monitor the degeneration and regeneration after injuries, which can provide objective basis in evaluating the clinical prognosis.

目的 探讨兔坐骨神经急性挤压伤MRI神经/肌肉信号比(SIR)在诊断外周神经损伤中的价值。方法 32 只新西兰白兔按钳夹力的不同随机分为A、B两组,建立兔坐骨神经急性挤压伤模型,于损伤后1、2、4、8周分别行双侧坐骨神经MR扫描,测量双侧坐骨神经各序列SIR值。结果 神经挤压伤后,除T1WI上无明显改变,在其余四序列上SIR均不同程度升高,1周时神经远段SIR升高,2周时SIR达高峰,4周时开始下降,8 周时下降较明显,与损伤后神经退变和再生及肢体功能的动态变化相一致。损伤侧神经远段SIR明显高于对照侧(P<0.001)。结论 SIR动态测量可直观、客观、无创性反映神经退变和再生的过程,为临床判断预后提供客观依据。

Objective:To study the clinical value of high-frequency ultrasonography on observing the acute crush injury of sciatic nerve in rabbits.Methods: A total of 16 rabbits were randomly divided into four groups according to different observation time.Models of acute crush injury of sciatic nerve in rabbits were established,and were (observed)by high-frequency ultrasonography 1,2,4 and 8 weeks respectively after damage.The internal radius of bilateral sciatic nerves were measured on the same levels.Results:The echoism...

Objective:To study the clinical value of high-frequency ultrasonography on observing the acute crush injury of sciatic nerve in rabbits.Methods: A total of 16 rabbits were randomly divided into four groups according to different observation time.Models of acute crush injury of sciatic nerve in rabbits were established,and were (observed)by high-frequency ultrasonography 1,2,4 and 8 weeks respectively after damage.The internal radius of bilateral sciatic nerves were measured on the same levels.Results:The echoism and internal radius of sciatic nerves were changed after the acute crush injury.The change was consistent to the dynamic change of the degeneration and regeneration of nerve and the function of limbs after damage.Conclusion:High-frequency ultrasonography reflects the course of nerve degeneration and regeneration straightly,which provides a new morphological diagnostic method for peripheral nerve damage.

目的:运用高频超声观察兔坐骨神经急性挤压伤,探讨其临床诊断价值。方法:按观察时间的不同将16只健康家兔随机分为4组。建立兔坐骨神经急性挤压伤模型,损伤后第1、2、4、8周,分别应用高频超声在同一水平上观察双侧坐骨神经的变化。结果:坐骨神经挤压伤后,其声像图和内径均有变化,且与神经损伤后退变、再生及肢体功能的动态变化相一致。结论:高频超声可直观地反映神经退变和再生的过程,提供了诊断外周神经损伤的新方法,对临床判断和预后提供客观依据。

 
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