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辅佐细胞
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  accessory cell
     AIM: To observe the culture operation technique and reasonable culture time of immunity accessory cell dendritic cells (DCs) obtained from bone marrow.
     目的:观察从骨髓来源的免疫辅佐细胞树突状细胞的培养操作技术及合理的培养时间。
短句来源
  accessory cells
     Role of accessory cells in the activation of T cells induced by monoethyl phosphate
     辅佐细胞在磷酸一乙脂激活γδT细胞中的作用
短句来源
     INTERACTION OF ACCESSORY CELLS WITH SPLENIC LYMPHOCYTE AFTER WHOLE-BODY X-IRRADIATION OF MICE
     小鼠全身照射后辅佐细胞与脾淋巴细胞间的相互作用
短句来源
     However, the addition of accessory Cells obviously enhanced the prolif-eration of T cells induced by MEP and IL-2,and the effect was obviously greater than that by IL-2 alone.
     加入辅佐细胞能大大促进MEP和IL-2联合激活γδT细胞的作用,且明显强于IL-2的单独作用。
短句来源
     Objective: Study of the role of accessory cells in the activation of T cells by nonpeptidic antigen monoethyl phosphate(MEP) .
     目的:研究辅佐细胞在非肽类抗原MEP激活γδT细胞中的作用及机制。
短句来源
     Substance P has a variety of physiological functions, it can influence the proliferation and synthesis of cytokine of lymphocytes as well as regulate the activity and the synthesis of cytokine of accessory cells and other immunocyte, so substance P participates in the process of immune regulation.
     P物质可以影响淋巴细胞的增殖和细胞因子的合成 ,并能调节辅佐细胞合成细胞因子和其它一些免疫细胞的活性 ,从而参与免疫调节 ;
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  “辅佐细胞”译为未确定词的双语例句
     Cell reconstitution experiments showed that aside from enhancing effect of RI being mainly on responsiveness of T lymphocytes, it could also increase accessory funtion of spleen adherent cells.
     细胞重组试验发现,维胺酯作用于淋巴细胞和辅佐细胞,但以前者为主。
短句来源
     These data showed that the isolated T and B cell samples were highly purified.
     这些结果证明,B细胞在T细胞丝裂原反应中可作为辅佐细胞,起着与单核-巨噬细胞相似的辅佐作用。
短句来源
     Conclusions:DCs are important assisted cells in T cells proliferation. They are potent stimulators in allogeneic mixed lymphocyte reaction.
     结论 :DCs是T淋巴细胞增殖反应中的重要辅佐细胞 ,具有良好的刺激同种T淋巴细胞增殖的能力
短句来源
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  accessory cell
It is concluded, therefore, that inhibition of the proliferative response to accessory cell-dependent mitogens may result from a dose-dependent destruction by Be2+ of the macrophage/adherent cell population.
      
A variety of intra-accessory cell and oocyte/accessory cell communications were identified.
      
A non-T:non-B accessory cell in peritoneal washout or spleen-cell suspensions facilitates T-cell proliferative responses to the mitogen, concanavalin A.
      
Utilizing monoclonal antibody, we show that this accessory cell bears the same I-A- and I-E-subregion controlled determinants as found on B cells.
      
In addition, the same accessory cell bears a Tla (Qa-1?)-region and an I-J-subregion controlled determinant.
      
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  accessory cells
Accessory cells were studied in early spermatogenesis of flatfishes Glyptocephalus stelleri and Pleuronectes pinnifasciatus using transmission electron microscopy.
      
The morphological organization of accessory cells in G.
      
Phagocytic Activity of Accessory Cells in the Gonad of the Sea Urchin Strongylocentrotus nudus
      
The role of B cells and accessory cells in the neonatal response to TI-2 antigens
      
Neonatal accessory cells such as macrophages and dendritic cells (DCs) appear to produce less stimulatory cytokines and an overabundance of inhibitory cytokines.
      
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Effects of retinoic acid (RA) and N- (P-etoxycarbopgdnyl) retinamide (RI) on syngeneic cytotoxic T lymphocyte (CTL) induction and mixed lymphocyte tumor cell culture (MLTC) were investigated. After immunizing DBA/2 mice with syngeneic L5178Y lymphoma, retinoids (RA, 50μg/mouse/ d; RI, 100, 300 or 500μg/mouse/d) administered i.p. to mice for 5 days could enhance both CTL induction and MLTC in vitro. Cell reconstitution experiments showed that aside from enhancing effect of RI being mainly on responsiveness of...

Effects of retinoic acid (RA) and N- (P-etoxycarbopgdnyl) retinamide (RI) on syngeneic cytotoxic T lymphocyte (CTL) induction and mixed lymphocyte tumor cell culture (MLTC) were investigated. After immunizing DBA/2 mice with syngeneic L5178Y lymphoma, retinoids (RA, 50μg/mouse/ d; RI, 100, 300 or 500μg/mouse/d) administered i.p. to mice for 5 days could enhance both CTL induction and MLTC in vitro. Cell reconstitution experiments showed that aside from enhancing effect of RI being mainly on responsiveness of T lymphocytes, it could also increase accessory funtion of spleen adherent cells.

本文报道维甲酸和维胺酯对诱导同基因小鼠杀伤性T细胞的产生和淋巴细胞增殖反应的作用。结果表明,连续5d给维甲酸和维胺酯,细胞毒T细胞的杀伤效应加强,后者的作用更为明显,亦可加强淋巴细胞的增殖反应。细胞重组试验发现,维胺酯作用于淋巴细胞和辅佐细胞,但以前者为主。

Previous studies have shown that hu-man B lymphocytes are effective accessorycells in mitogen responses.In this study,the ability of mouse splenic B cells to actas accessory cells in Con-A response hasbeen investigated.The results showed thatboth of the resting and LPS-activated Blymphocytes were very effective on en-hancing T cell proliferative responses toCon-A, but,functionally. the LPS-activatedB lymphocytes were much more effective ascompared with resting B lymphocytes. Weconsidered that it was important...

Previous studies have shown that hu-man B lymphocytes are effective accessorycells in mitogen responses.In this study,the ability of mouse splenic B cells to actas accessory cells in Con-A response hasbeen investigated.The results showed thatboth of the resting and LPS-activated Blymphocytes were very effective on en-hancing T cell proliferative responses toCon-A, but,functionally. the LPS-activatedB lymphocytes were much more effective ascompared with resting B lymphocytes. Weconsidered that it was important to examinewhether the accessory cell function which Blymphocytes appears was to be geneticallyrestricted.To answer this question, the fol-lowing experiments were established: the Tcells from C57BL/6 mouse spleen as respond-ing cells(T_1) interacted with B cells obtain-ed from BALB/c mouse spleen as accessorycells (B_2) or vice versa.The results indicat-ed in table 1 demonstrated that accessorycell function of B lymphocytes in T cellproliferation to Con-A stimulation was ge-natically unrestricted.In additior, the effectof B lymphocytes in the production of in-terleukin-2,which was produced by T lym-phocytes after Con-A stimulation, was stu-died.In this experiment, the resting B cells,LPS--activated B cells and macrophageswere added as accessory cells.The resultsshown in table 2 indicated that the produc-tion of interleukin-2 markedly increasedin the presence of B cells.The results alsorevealed that the accessory function of acti-vated B cells was much more effective thanthat of the resting B cells and macrophagesinthe production of interleukin-2. Takentogether these results strongly demonstratedthat B lymphocytes to serve as accessorycells played an important role in T cellproliferative responses to Con-A and in theproduction of interleukin-2.

小鼠脾细胞经两次贴壁除去巨噬细胞,再经两次尼龙毛柱纯化T细胞,尼龙毛粘附的B细胞用抗θ血清加补体去除残余的T细胞后,得到高度纯化的B细胞,在体外用细胞重组实验方法观察B细胞在ConA反应中的作用。结果表明,静止B细胞和细菌脂多糖活化的B细胞均能非常显著地辅佐T细胞对ConA刺激的增殖反应,B细胞这种作用不受组织相容性抗原约束。B细胞还能辅佐T细胞产生IL-2,这证明B细胞具有辅佐细胞功能。

In this study, we have investigated the capacity of human tonsillar B lymphocytes to serve as accessory cells for T cell mitogen responses in vitro. Human tonsillar mononuc-lear cell suspensions were depleted of monocy-te-macrophages(Mo-Mφ) by sequential twice glass adherence. Then, T and B lymphocytes were successfully isolated by means of sequen-tial passage over two nylon wool columns. The isolated T cell samples contain 98.3± 0.5% of Leu 1 positive cells, 0.5±0.1% of Leu12 positive cells and 0% of LeuM 3...

In this study, we have investigated the capacity of human tonsillar B lymphocytes to serve as accessory cells for T cell mitogen responses in vitro. Human tonsillar mononuc-lear cell suspensions were depleted of monocy-te-macrophages(Mo-Mφ) by sequential twice glass adherence. Then, T and B lymphocytes were successfully isolated by means of sequen-tial passage over two nylon wool columns. The isolated T cell samples contain 98.3± 0.5% of Leu 1 positive cells, 0.5±0.1% of Leu12 positive cells and 0% of LeuM 3 posi-tive cells; the isolated B cell samples consist of 96.9±1.2% of Leu 12 positive cells, 1.0 ±0.3% of Leu 1 positive cells and 0.9±0.5 % of LeuM 3 positive cells. These data showed that the isolated T and B cell samples were highly purified.

人扁桃腺淋巴细胞经两次贴壁除去单核-巨噬细胞后,再经连续两次尼龙毛柱处理,得到高度纯化的T和B细胞,在体外用细胞重组实验的方法,比较全面地观察了B淋巴细胞在体外T细胞丝裂原反应中的作用。结果证实,静止的B细胞和经A蛋白菌体试剂活化的B细胞均能非常显著地辅佐T细胞对ConA和PHA刺激的增殖反应,B细胞的这种作用不受HLA的约束。此外还观察了在PHA刺激T细胞产生IL-2反应中B细胞的作用,结果表明,加入B细胞,能明显辅佐T细胞产生IL-2。这些结果证明,B细胞在T细胞丝裂原反应中可作为辅佐细胞,起着与单核-巨噬细胞相似的辅佐作用。

 
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