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联合诱导分化
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  “联合诱导分化”译为未确定词的双语例句
    The Clinical Studies of Surgery Combined with Chemotherapy and Differentiation-inducing Therapy of Advanced Ovarian Serous Cystadenocarcinoma
    手术、化疗联合诱导分化治疗晚期卵巢浆液性囊腺癌的临床研究
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    All trans retinoic acid in the treatment of gastric carcinoma
    全反式维甲酸联合诱导分化治疗晚期胃癌的初步临床观察
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    All-Trans-Retinoic Acid in Treatment of Gastric Cancer
    全反式维甲酸联合诱导分化治疗晚期胃癌的初步临床观察
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    The Clinical Studies of Surgery Combined With Chemotherapy and Differentiation-inducing Therapy of Advanced Ovarian Serous Cystadenocarcinoma
    手术、化疗联合诱导分化治疗晚期卵巢浆液囊腺癌的临床研究
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    The Study of the Differentiation-inducing Effect of Tachypksin in Combination with n-Sodium But~ate , GinsenosideRgl on Human Gastric Adenocareinoma BGC-823 Cefls
    中国鲎鲎素对人胃腺癌BGC-823细胞的联合诱导分化研究
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cases of acute promyelocytic leukemia(APL) were treated with all trans retinoic acid(ATRA) combined with chemotherapy. 44 cases obtained complete remission(CR). The CR rate was 88%. By morphological, cytochemical and electronmicroscopic studies we found that APL cells in marrow from CR patients differentiated into mature cells after ATRA therapy and there was no obvious differentiation in APL cells from PR patients, which might be of prognostic significance.

用以维甲酸为主的联合诱导分化方案治疗50例初治APL,CR率为88%(44/50)。在治疗前、治疗中、骨髓CR期,应用细胞形态学、细胞化学和电镜动态观察。CR病例APL细胞有明显成熟分化表现。4例PR病人,成熟分化改变不明显,有一定判断预后意义

patients with acute promyelocytic leukemia (APL) were divided into 4 groups. 21 of them received RDA (all trans retinoic acid、1、25(OH) 2 vitamin D 3 and low dose Ara c), 11 of them received RD, 14 of them received all trans retinoic acid 60 mg~90 mg every day and 7 of them received all trans retinoic acid 40 mg every day. 49 of the 53(92.5%) the patients achieved complete remission. Days reached to complete remission in patients received RDA is significantly less than other group. Side effect of the patients...

patients with acute promyelocytic leukemia (APL) were divided into 4 groups. 21 of them received RDA (all trans retinoic acid、1、25(OH) 2 vitamin D 3 and low dose Ara c), 11 of them received RD, 14 of them received all trans retinoic acid 60 mg~90 mg every day and 7 of them received all trans retinoic acid 40 mg every day. 49 of the 53(92.5%) the patients achieved complete remission. Days reached to complete remission in patients received RDA is significantly less than other group. Side effect of the patients received all trans retinoic acid 40 mg/d is lower. The complete remission rate、WBC reached a peak and increasing times to have no significant difference among groups. Combined induction differentiation mechnism and all trans retinoic acid ideal dosage have been discussed.

将53例急性早幼粒细胞白血病患者按诱导分化治疗方案分为4组:RDA组21例,RD组11例,单用常规量RA组14例,单用小剂量RA组7例。治疗结果显示,总完全缓解率为92.5%,RDA组达CR需要的时间明显短于其它各组(P<0.05),小剂量RA组的副作用少于其它各组。CR率、白细胞达峰值的时间及白细胞增加的倍数各组间无明显差异。对联合诱导分化治疗方案及RA的合理剂量进行了讨论。

In order to maintain and analyze the differentially cDNAs, Which belong to the differentially expressed genes between colon cancer cells and cells induced by all trans retinoic acid and 1,25-(OH) 2D 3, and are obtained by SSH method, the subtracted products were linked with TA vector and transferred into E. coli. The results demonstrated that the contents in before and after induced subtracted cDNA library were 1.05×10 4 pfu and 1.49×10 4 pfu, respectively. As a result, the foundations for further studying...

In order to maintain and analyze the differentially cDNAs, Which belong to the differentially expressed genes between colon cancer cells and cells induced by all trans retinoic acid and 1,25-(OH) 2D 3, and are obtained by SSH method, the subtracted products were linked with TA vector and transferred into E. coli. The results demonstrated that the contents in before and after induced subtracted cDNA library were 1.05×10 4 pfu and 1.49×10 4 pfu, respectively. As a result, the foundations for further studying the pathogenic mechanism of colon cancer and therapy mechanism of inducing differentiation are established.

为保存和分析抑制性消减杂交 (SSH)获得的结肠癌经全反式维甲酸和 1 ,2 5-(OH) 2 D3联合诱导分化前、后的差异cDNA ,把消减产物与TA载体连接并转化到大肠杆菌中建立消减cDNA文库 .结果表明 :诱导前消减cDNA文库的容量为 1 .0 5× 1 0 4 pfu ,诱导后消减cDNA文库的容量为 1 .49× 1 0 4 pfu .本实验为进一步研究结肠癌的发病机制和诱导分化的机制提供了物质基础 .

 
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