After treatment with MPS of 85 cases suffering from malignant neoplasms treated with chemotherapy after operation , the level of leukocytes and the cell mediated immunity were raised obviously (P< 0. 05～ 0. 01 ) .
Chitin and its derivative can strengthen the function of resisting on the microorganism of many kinds of etiologies of organism through regulating the function of immune system of organism , have effect of suppressing to tumour cells, such as mouse MethA fibrosarcoma , S180 tumour, MM44 entity tumour and Lewis lung cancer, etc.
Guanidine-like compounds have been investigated since the first observations of their therapeutic potential some 30 years ago in fields of cancer and virology.
Epidermal Growth Factor Receptor (EGFR) is among the growth factor receptor kinases that have been implicated in as being important in cancer.
Inhibitive Effect of Prodigiosin on the Proliferation of Human Malignant Pancreatic Cancer Cells
Pancreatic cancer is not only common, but also extremely difficult to treat, for which it has been called "the challenge of the twenty-first century".
In this study, we find that prodigiosin could effectively inhibit the proliferation of human pancreatic cancer cells H8898 in a dose-and-time-dependent manner, with an IC50 of 75μmol according to the results of MTT and cell proliferation assays.
The combination of the above observations led to the hypothesis that at least parts of an immune reaction might promote tumour development, and indeed, many experiments specifically designed to answer this question support this prediction.
However, this "immunostimulation theory of tumour development" is neither explained in a satisfactory fashion nor universally adopted.
Combining the anti-tumour and haematopoiesis-stimulating activities in a single COX-2 inhibitor may have a positive clinical impact.
Tumour size, histological type, cellular and nuclear characteristics, mitotic index, vascular invasion, hormonal receptors and axillary lymph node status are biomarkers routinely used.
Tumour markers in breast cancer were ranked in categories reflecting their clinical utility, according to the American College of Pathologists.