Objective:This study aimed to investigate DNA ploidy and the expression of TGFβ1 in the endometrioid adenocarcinoma was for the view of neoplasm heterogeneity,to explore the machinery of molecular biology and genetics for the endometrioid adenocarcinoma.
Objective To investigate the expression and clinical significance of matrix metalloproteinase-2(MMP-2) and tissue inhibitor of matrix metalloproteinase-2 (TiMP-2) and their correlations with angiogenesis in epithelial ovarian neoplasm.
Experimental Study of Sperm Protein 17 as a Target for diagnosis and treatment of Gynecological Cancers
精子蛋白17作为妇科肿瘤诊断治疗靶标的基础研究
and immunohistochemistry was used to evaluate the expression of PTEN protein in epithelial ovarian cancers and benign epithelial ovarian tumors as well as normal ovarian tissues.
This indicated that part of P~16 gene changed. The rate of the mutation was 53.57%(15/28). Of all these ,the rate of P~16 genetic alteration of the benign ovarian tumors was 72.7%(8/11)and that of the neutral ovarian tumors was 75%(3/4),and that of the ovarian cancers was 30.8%(4/13).
The clinicopathologic features of intraductal papillary mucinous neoplasms of the pancreas
Effect of antioxidant β-(4-hydroxy-3,5-ditertbutylphenyl)Propionic acid (phenosan) on the development of malignant neoplasms
pylori infection is associated with chronic gastritis, gastric and duodenal ulcers, and malignant neoplasms.
Formation of the blood supply system is a critical step in malignant transformation of neoplasms which results in the penetration of tumor cells into neighboring tissues and metastatic growth.
Exploiting Oxidative Stress and Signaling in Chemotherapy of Resistant Neoplasms
Since first described in 1982, intraductal papillary mucinous neoplasm (IPMN) has been the preferred term to describe the proliferation of the pancreatic ductal epithelium.
An analysis of clinico-pathologic features of intraductal papillary mucinous neoplasm of the pancreas
The data considered in the paper indicate that a tumor clone resulting from cell transformation, in order to develop into an overt neoplasm, should overcome a microenvironmental constraint.
Cases of a hereditary malignant neoplasm giving rise to the formation of multiple macrovilli in the cardiac portion of the stomach have been found in Microtus abbreviatus (Microtinae, Cricetidae), a vole endemic to St.
The pathogenic neoplasm serves as a preadaptation for the growth of symbiotic flora in the stomach.
Immunohistochemical analysis revealed a high expression level of hSef in kidney, testis, and the corresponding carcinoma tissues.
Effect of down-regulating VEGF on proliferation of colon carcinoma cell HT-29
Cancer-related genes harbored in the loss regions containing a high frequency of hepatocellular carcinoma (HCC) were selected.
The purified 19peptide directly inhibited proliferation and migration of murine B16 melanoma cells, SMMC-7721hepatoma carcinoma cells and human umbilical vein endothelial cells (HUVEC).
We recognized and honoured the important contributions of these Chinese pioneers in portal hypertension, recurrent pyogenic cholangitis, hepatocellular carcinoma and liver transplantation.
The complex nature of DNA methylation patterns extends to carcinogenesis because global DNA hypomethylation is found in the same cancers displaying hypermethylation elsewhere in the genome.
A wide variety of cancers display both DNA hypomethylation and hypermethylation, and either of these types of changes can be significantly associated with tumor progression.
Furthermore, various DNA demethylation methodologies have been shown to increase the formation of certain types of cancers in animals, and paradoxically, DNA hypermethylation can cause carcinogenesis in other model systems.
Hypermethylation of RASSF1A was frequently found in most major types of human tumors including lung, breast, prostate, pancreas, kidney, liver, cervical, thyroid and many other cancers.
The thermostable fraction of serum samples from patients with ovarian, uterus, and breast cancers and benign ovarian tumor was analyzed using two-dimensional electrophoresis combined with MALDI-TOF(-TOF)-mass spectrometry.