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神经再生微环境
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  “神经再生微环境”译为未确定词的双语例句
     Effect of electric fields on the protein in nerve regen-eration conditioned fluid
     电场对神经再生微环境中活性蛋白的影响
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     Recently the study on Neuro-immuno-endocrinology showed that the specific T lymphocytes induced by the injury of the peripheral nerves had potent potential in improving the nerve regenerative microenvironment.
     研究表明,火器性坐骨神经断裂伤是合并全身创伤的一种特殊类型神经损伤,火器伤不仅严重损害神经再生微环境,而且还严重抑制机体免疫功能,这使得火器性周围神经断裂伤后的修复十分困难。
短句来源
     This would provide a bright future in improving the nerve regeneration after firearm peripheral nerve’s disrupted injury through regulating T lymphocyte’s function.
     最近对神经-免疫-内分泌网络的研究发现:周围神经损伤后诱发的特异性T淋巴细胞具有从多方面调节神经再生微环境能力而在神经再生中起着重要作用。
短句来源
     1.The effect of T lymphocytes on the nerve regenerative microenvironment after sciatic nerve’s incised injury: T lymphocyte induced by the sciatic nerve’s incised injury can improve the regenerative microenvironment: ①It can express NGF (Nerve growth factor) and BNDF(Brain-derived neurotrophic factor) by themselves;
     1.T淋巴细胞对坐骨神经切割伤后神经再生微环境的影响(1)利用已建立的免疫耐受组、免疫增强组、免疫正常对照组动物模型,建立坐骨神经切割伤模型,检测下列神经再生微环境指标:①T淋巴细胞本身是否能表达NGF、BDNF,以及神经组织内NGF、BDNF水平; ②巨噬细胞趋化、吞噬处理变性髓鞘能力;
短句来源
     ②It can increase the levels of NGF and BDNF in the injuried nerve;
     ③雪旺细胞增殖水平。 (2)结果:①T淋巴细胞本身可以表达NGF、BDNF等多种NTFs,并提高神经再生微环境内NTFs水平。
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     Study of nerve regeneration process and microenvironment in the regeneration chamber
     神经再生室中神经再生过程和微环境的研究
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     Introducation of a new study model of never regeneration chamber and microenvironment
     神经再生室与微环境研究的新模型
短句来源
     (4)Acceleration of nerve regeneration.
     ( 4 )加速神经再生
短句来源
     Effect of electric fields on the protein in nerve regen-eration conditioned fluid
     电场对神经再生微环境中活性蛋白的影响
短句来源
     Objective To investigate the process of nerve regeneration and cellular component in nerve regeneration chamber.
     目的 探讨再生室中神经再生过程、微环境成份及作用。
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Abstract The think fluid of autogenus nerve wes filled in a tube of HAN (Human Ammion Memberane)wich has been treated with glutaraledhyde. This graft was placed into a 10mm gap of sciatic nerve of rats. Autogenous nerve graft and HAM tube without the fluid were used as controls.At 12 weeks after the operation the sciatic nerve wete examined by histological, electric microscopical and electro physiological means. The results showed that the 10mm gap if sciatic nerve of rat was repaired successfully. Thus it...

Abstract The think fluid of autogenus nerve wes filled in a tube of HAN (Human Ammion Memberane)wich has been treated with glutaraledhyde. This graft was placed into a 10mm gap of sciatic nerve of rats. Autogenous nerve graft and HAM tube without the fluid were used as controls.At 12 weeks after the operation the sciatic nerve wete examined by histological, electric microscopical and electro physiological means. The results showed that the 10mm gap if sciatic nerve of rat was repaired successfully. Thus it was considered that HAM tube filled with the fliud .might be a good method for repairing the peripheral nerve defer.Keywoads: perphelal nerve; nerve defect, nerve regeneration, human ammion mmemberane

将自体神经组织浆充填于经成二醛处理的人羊膜管内,模拟自体神经移植的神经再生微环境,研究其修复大鼠10mm坐骨神经缺损的可行性,并与自体神经移植、单纯中空人羊膜管组对比。术后3周,经光镜、电子显微镜及电生理检测.结果证实再生神经纤维顺利通过缺损区,长入神经远端,提示该模型在一定程度上模拟了周围神经再生的微环境条件,成功修复了大鼠10mm坐骨神经缺损。我们认为实验所设计的模型可能是修复周围神经缺损的一种较好的方法。

A 0.6cm segment of right common peroneal nerve was resected in 60 Sprague Dawley rats. The nerve defects were bridged by adhering the epineurium with autogenous nerve, vein, skeletal muscle, tendon and silastic tube. According to the kinds of the grafts used, the rats were divided into 5 groups. In 6 and 12 weeks after operation, the effect was assessed by motor nerve conduction velocity, weight of the anterior tibial muscle, number of distal axons and histological examination. It was demonstrated that the...

A 0.6cm segment of right common peroneal nerve was resected in 60 Sprague Dawley rats. The nerve defects were bridged by adhering the epineurium with autogenous nerve, vein, skeletal muscle, tendon and silastic tube. According to the kinds of the grafts used, the rats were divided into 5 groups. In 6 and 12 weeks after operation, the effect was assessed by motor nerve conduction velocity, weight of the anterior tibial muscle, number of distal axons and histological examination. It was demonstrated that the result from autogenous nerve graft was superior to other grafts in all aspects and that of the vein graft was better than the other three. The characteristics of the nerve regeneration and the process of maturation in different types of the grafts were discussed. The related microenvironment which caused the difference was also discussed.

修复神经缺损的材料甚多,但至今尚未见各种材料的比较研究。为了比较自体神经、肌肉、静脉、肌腱及硅橡胶修复神经缺损的效果,选用SD大白鼠,切断腓总神经,制成0.6cm缺损,分别用不同移植物桥接缺损。于术后6周、12周在电生理、胫前肌称重、远端轴突计数及组织学等方面进行综合分析评价。结果表明:自体神经移植在各方面均优于其它移植体,而静脉组又优于另外3组。对各种移植体中神经再生的特点及其成熟过程进行了讨论,并探讨了形成这种差别的有关神经再生微环境的影响。

Objective To explore the expression and distribution of ciliary neurotrophic factor(CNTF) mRNA and its protein in laryngeal nerve regeneration Methods The recurrent laryngeal nerves were sectioned and then sutured in twelve dogs Both proximal and distal stumps of sutured region were sectioned on different post operative days and the sections were separately used for CNTF immunohistochemistry and CNTF mRNA in situ hybridization The area and intensity of reactive product were measured by computer image...

Objective To explore the expression and distribution of ciliary neurotrophic factor(CNTF) mRNA and its protein in laryngeal nerve regeneration Methods The recurrent laryngeal nerves were sectioned and then sutured in twelve dogs Both proximal and distal stumps of sutured region were sectioned on different post operative days and the sections were separately used for CNTF immunohistochemistry and CNTF mRNA in situ hybridization The area and intensity of reactive product were measured by computer image processing system Results Strongly reactive product of CNTF mRNA and its protein deposited in myelin related Schwann cells in normal laryngeal nerves At week 2 following neurorrhaphy, there was very little hybridization signal and detectable CNTF immunoreactivity in distal stump and no regenerated nerve fibbers were found At week 3, reactive product of CNTF mRNA and its protein was detected in thin Schwann cell processes ensheathing regenerated axons, while reactive product was not found in the proliferating Schwann cells which didn't ensheathe axons CNTF immunoreactivity was also detected in the regenerated nerve axons After longer survival times, hybridization signal and the CNTF immunoreactivity in Schwamm cells became more widespread, and the area and intensity of reactive product significantly increased , but even at the longest survival time, they were still significantly less than those in intact nerve The same change of CNTF mRNA and its protein was observed in a short segment proximal to the sutured region Conclusion CNTF expression could depend on Schwann cell axon regeneration The level of CNTF expression stands in striking contrast to the up regulation of nerve growth factor in peripheral nerve degeneration and regeneration These suggest that the exogenous CNTF might provide a supportive environment for axonal regeneration

目的 阐述喉返神经修复后神经干睫状神经营养因子 (ciliaryneurotrophicfactor,CNTF)的表达及分布。方法 切断并立即缝合犬喉返神经为神经修复再生模型 ,采用原位杂交及免疫组织化学方法检测CNTFmRNA及其蛋白的表达 ,结合图像分析技术 ,测定反应产物的灰度值及面积百分率。结果 正常神经CNTFmRNA及其蛋白反应产物位于包绕轴突及髓鞘的雪旺细胞中。神经修复术后 2周神经纤维降解 ,CNTFmRNA及其蛋白表达迅速下降 ,3周后随着神经的再生CNTFmRNA及其蛋白表达逐渐增加 ,表达产物仍位于包绕再生轴突及髓鞘的雪旺细胞中 ,CNTF蛋白还出现于再生的轴突中。 18周后虽然神经再生完成 ,但反应产物灰度值及面积百分率仍明显低于正常状态。结论再生神经CNTF的表达与轴突再生有关 ;表达呈下调型 ,提示补充外源性CNTF可能改善神经再生微环境

 
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