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临床特征
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Adamantinoma is a malignanttumor rarely affecting the long bones.Three cases of adamantinoma of thetibia are reported. All of these caseswere treated by local excision butthe tumor recurred. In case 3, therewere inguinal and pulmonary metas-tases. She died from metastases oneyear after amputation of the affectedlimb. The findings of the tumorunder light microscope were inagreement with the theory that thetumor was of epithelial origin. Theelectron microscopic study of theneoplasm in this case revealed that,the...

Adamantinoma is a malignanttumor rarely affecting the long bones.Three cases of adamantinoma of thetibia are reported. All of these caseswere treated by local excision butthe tumor recurred. In case 3, therewere inguinal and pulmonary metas-tases. She died from metastases oneyear after amputation of the affectedlimb. The findings of the tumorunder light microscope were inagreement with the theory that thetumor was of epithelial origin. Theelectron microscopic study of theneoplasm in this case revealed that,the cytoplasm of tumor cells wasvery scanty. There was a large amountof bundles of tonofilaments and freeribosomes, but other cell organelleswere seldom seen. At portions oftumor cell mass, discontinuous basalmembrane adjacent to the interstitialtissue were demonstrated. Microvilliwere found to extend into intercellularspaces. There were also intercellulardesmosomes. Based on these findings,it seems that this tumor is mostprobably originated from squamouscells. Because this tumor does nothave typical clinical and roentgeno-graphic characteristics, biopsy isalways necessary for its diagnosis.Local excision of the tumor is usuallyfollowed by recurrence, therefore,amputation of the involved extremityis proposed.

本文报告3例少见的胫骨造釉细胞瘤,对其中2例进行了追踪观察,1例随访近4年无复发及转移;1例早期出现腹股沟淋巴结转移,经截肢术后一年死于广泛性肺转移。并介绍了临床、病理发现和一例电子显微镜研究。讨论了此瘤组织发生学、临床特征、肿瘤性质和治疗。

This paper reported 63 cases with chronic radiation skin injury.The pa-thogenesis of radiation skin injury was discussed and its clinic features weredescribed.with the exception of 5 cases with dysepulotic postoperation incis-ion,typical chronic radiation skin injury in various degrees was observedin all of the remaining cases.The principles and procedures of treatmentwere discussed and in particalar,a new procedure is presented,in whichpharmacotherapy(using a biological preparation containing macroglobulin...

This paper reported 63 cases with chronic radiation skin injury.The pa-thogenesis of radiation skin injury was discussed and its clinic features weredescribed.with the exception of 5 cases with dysepulotic postoperation incis-ion,typical chronic radiation skin injury in various degrees was observedin all of the remaining cases.The principles and procedures of treatmentwere discussed and in particalar,a new procedure is presented,in whichpharmacotherapy(using a biological preparation containing macroglobulin α_2)is combined with surgical intervention.follow-up studies wer made on 46cases showing that simple pharmacotherapy is effective in 24 cases out of 32cases,while the remaining 14 cases,treated by pharmacotherapy combinedwith surgical operation all showed positive result.

本文收集了慢性放射性皮肤损伤63例。讨论了放射性皮肤损伤的病理过程,并且描述了临床特征。除5例手术切合口愈合不良外,其余病例均可见到程度不同的典型慢性放射性皮肤病变。最后叙述了治疗原则和措施,着重介绍了一种新的治疗方法——药物疗法(应用含甲_2巨球蛋白的生物制剂)和手术疗法相结合。在进行追踪观察的46例中,单纯药物治疗32例,有效者24例;结合手术治疗14例,无一例失败。

A comparison of the clinical features,the chest radiographs,the laboratory find- ings of pleural effusion and effect of anti-tuberculosis treatment was made between cases of malignant effusion caused by lung cancer(45 patients)and those of tubercu- lous pleural effusion(16 patients).The following points including the patients'age, the nature of the fluid and its cytological findings,the course and effect of anti- tuberculosis treatment,and the tuberculin test were considered to be rather helpful in differentiating...

A comparison of the clinical features,the chest radiographs,the laboratory find- ings of pleural effusion and effect of anti-tuberculosis treatment was made between cases of malignant effusion caused by lung cancer(45 patients)and those of tubercu- lous pleural effusion(16 patients).The following points including the patients'age, the nature of the fluid and its cytological findings,the course and effect of anti- tuberculosis treatment,and the tuberculin test were considered to be rather helpful in differentiating the two conditions.

对肺癌引起的癌性胸膜炎45例与结核性胸膜炎16例的临床特征、放射线检查和胸水化验所见以及试验抗癌治疗的效果进行了比较。这两种疾患的表现虽较相似,但仍各有其特点,尤以下述几点对两者的鉴别有较大的帮助;1.年龄;癌性发病年龄较高,平均52.1岁,结核性年龄较轻,平均为33.2岁。2.胸水;癌性多为血性,且含有较多的中性粒细胞,多数患者的胸水能找到恶性细胞。3.结核菌素试验;癌性多阴性,结核多为阳性。4.试验抗痨治疗;对癌性无效。如不及时抗癌治疗,多在6个月内死亡。而结核性经抗痨后多在1个月内明显好转。

 
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