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肺腺癌
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  lung adenocarcinoma
    Determination and Comparison of Plasma Membrane Lipid Region Fluidity of High and Low-Metastatic Human Lung Adenocarcinoma Cell Lines
    高低转移性人肺腺癌细胞膜脂区流动性的测定及比较
短句来源
    EFFECTS OF 5-FLUOROURACIL ON CYCLIC GMP LEVEL OF THE LUNG ADENOCARCINOMA IN MICE
    5-Fu对小鼠肺腺癌cGMP水平的影响
短句来源
    Establishment a cisplatin resistant human lung adenocarcinoma A549 cell subline
    顺铂诱导人肺腺癌A549细胞系多重抗药性的形成
短句来源
    Objective:To prepare folate conjugated bovine serum album nanoparticles and observe the targeting effect of folate-BSANP to A549 cells, the cells of human lung adenocarcinoma, on the basis of that folate receptors are frequently overexpressed on some kind of tumor cellular membrane, but they are expressed on normal tissue at a low lever or not.
    叶酸受体在一些肿瘤细胞膜上呈高水平表达,但在正常组织上不表达或低水平表达。 据此制备叶酸偶联白蛋白纳米粒(folate conjugated bovine serum album nanoparticles,folate-BSANP,F-BSANP),并观察其对人肺腺癌A549细胞的靶向效果。
短句来源
    We determined and comparied the plasma membrane lipid region fluidity of two tumor cell lines, the high-metastatic human lung adenocarcinoma cell line (Anip-973) and its low-metastatic parent cell line(AGZY-83a), by fluorescence polarization with a probe DPH (1,6-diphenyl-1,3,5-hexatriene). All tumor cells were synchronized at early S-phase by the double thymidine block.
    本文应用荧光探剂DPH(1,6-dipheny1-1,3,5-hexatriene)及荧光偏振技术,对高转移性的人肺腺癌细胞系Anip-973及其低转移性的母系AGiY-83a,经S相(S-phase)同步后细胞膜的流动性进行了测定并作了对比分析。
短句来源
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  “肺腺癌”译为未确定词的双语例句
    The purified polypeptides JNY-1 and JNY-2 may both inhibit the growth of tumor cells Glc-82 in vitro, and the IC_(50) values were 23.33μg/ml and 9.59μg/ml respectively measured by MTT assay.
    纯化产物JNY-1和JNY-2具有体外抗肿瘤活性,对Glc-82肺腺癌细胞JNY-1的IC_(50)为23.33μg/ml; JNY-2的IC_(50)为9.59μg/ml。
短句来源
    Methods: (1) The antiproliferative effect of AL68 series against A549 and Lovo in vitro was observed by MTT assay.
    方法:(1)采用MTT法对AL68系列化合物进行初步筛选,观察它们在体外对人体肺腺癌A549细胞株和人体结肠癌LOVO细胞株的增殖抑制作用。
短句来源
    METHODS In vitro anti-tumor assay were performed to pulmonary adenoma cells A549 and human liver cancer cells Bel-7402,MTT method was employed and half-inhibitory concentrations(IC_ 50 )were observed.
    方法采用MTT法进行药物体外对肺腺癌细胞A549和人肝癌细胞Bel-7402抗肿瘤实验,测定IC50;
短句来源
    RESULTS IC_ 50 of 17aα-D-homo-ethynylestradiol-3-acetate in vitro to A549 and Bel-7402 cells were 12.28μg·mL -1 and 17.79μg·mL -1 ,respectively.
    结果17aα-D-高炔雌二醇-3-乙酯体外肺腺癌细胞A549和人肝癌细胞Bel-7402的IC50分别为12.28μg·mL-1、17.79μg·mL-1;
短句来源
    Targeting Treatment with Imunotoxin Trichosanthin Conjugated with
    抗人肺腺癌单克隆抗体—天花粉蛋白免疫毒素对荷人肺腺癌裸鼠模型的导向治疗
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  lung adenocarcinoma
Impact of siRNA targeting pirh2 on proliferation and cell cycle control of the lung adenocarcinoma cell line A549
      
Taken together, the inhibition of pirh2 expression in the lung adenocarcinoma cell line A549 resulted in reduced tumor cell growth via the inhibition of cell proliferation, the activation of apoptosis and the interruption of cell cycle transition.
      
Arachidonic Acid Metabolism in Growth Control of A549 Human Lung Adenocarcinoma Cells
      
The role of individual eicosanoids of the arachidonic acid (AA) cascade in the growth control of A549 human lung adenocarcinoma cells has been studied.
      
They exhibit similar phototoxicities on the cells of A549 human lung adenocarcinoma, which are 40- and 100-fold higher than those of chlorin p6 and the clinically used Photogem, respectively, and are not toxic in the absence of light irradiation.
      
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This paper reports that cultivation of the advanced infective larvae (L_3+)of periodic Brugia malayi from the infective larvae(L_3)were obtained in vitro in culture medium RPMI1640 supplemented with 20% heatinactived new born calf serum and a feeder layer of human lung adenocarcinoma cell line (GLC-82). In this culture system the larvae survived for 27 days and increased by 21.9% and 33.2% in average length at 13 days and 27 days in vitro, respectively. The report is the first to describe the application of...

This paper reports that cultivation of the advanced infective larvae (L_3+)of periodic Brugia malayi from the infective larvae(L_3)were obtained in vitro in culture medium RPMI1640 supplemented with 20% heatinactived new born calf serum and a feeder layer of human lung adenocarcinoma cell line (GLC-82). In this culture system the larvae survived for 27 days and increased by 21.9% and 33.2% in average length at 13 days and 27 days in vitro, respectively. The report is the first to describe the application of human cancerous cell line on in vitro cultivation of the infective larvae of human filarial parasites. The result suggests that GLC-82 cell line may contain some substances facilitating survival, growth and activity of the thirdstage larvae of periodic Brugia malayi in vitro.

本文报道周期型马来丝虫感染期幼虫,在含有20%灭活小牛血清和人肺腺癌细胞系的RPMI1640培养液中培养至后期感染期幼虫,并存活27天。在培养后13天和27天,平均虫体长度分别增加21.9%和33.2%。本文为首次报道在人体寄生丝虫感染期幼虫体外培养中应用人体癌细胞系,结果表明人肺腺癌细胞系可能含有某些物质有利于马来丝虫感染期幼虫在体外培养条件下的生存、生长和活动。

Asparagus was one of the well-known traditional Chinese medicinal herbs back to thousand years but recently was reported to bewith anticancer activity. In the present work the anticancer and immune-stimulation effect with the extracts from Asparagus Officinalis linn werestudied. We have found that Asparagus can inhibit colony growing in certainconcentrations, of human nasopharyngeal cancer CNE cells, humancervical cancer HeLa cells, human esophageal cancer Eca-109 cells as wellas mouse pulmonary adenocarcinoma...

Asparagus was one of the well-known traditional Chinese medicinal herbs back to thousand years but recently was reported to bewith anticancer activity. In the present work the anticancer and immune-stimulation effect with the extracts from Asparagus Officinalis linn werestudied. We have found that Asparagus can inhibit colony growing in certainconcentrations, of human nasopharyngeal cancer CNE cells, humancervical cancer HeLa cells, human esophageal cancer Eca-109 cells as wellas mouse pulmonary adenocarcinoma LA-795 cells. The cytotoxic effectof Asparagus increased with the concentration or the time of exposure toit. There was a little difference in the pattern of the survival curves.The most sensitive cells to the drug were LA-795 (D_0=1. 3%), then CNEcells and HeLa cells (D_0=2. 1% and 2. 6% respectively), the Eca-109 cellsappeared to have a larger value of D_0(4. 4%). The effective concentrationwas about 12% Asparagus. The growth of solid tumor of pulmonary adenocarcinoma in LA-739mice could be layed by Asparagus and the doubling time of tumorregrowth delay was determined to be 4 days. The ER was about 1. 5. Asparagus is a biological respollse modifier at lower concentration(0. 1-1. 0%). Our experimental results showed that Asparagus couldstimulate the proliferation of peripheral lymphocyte and the effect ofIL-2 may be doubled if used in combination with Asparagus. The effectof immunal stimulation was similar in mice, normal subjects, and cancerpatients.

一定浓度的芦笋原汁(Asparagus Officinalis Linn)对小鼠肺腺癌(LA-795)、人鼻咽癌(CNE)、人宫颈癌(HeLa)和人食管癌(Eca109)离体细胞有明显的细胞毒性作用。对克隆源性细胞的杀伤程度与芦笋汁浓度和接触时间成正相关。各细胞系药敏反应不同,LA-795细胞最为敏感(D_o=1.3%),CNE和HeLa细胞次之(D_o=2.1%和2.6%),Eca109细胞较不敏感(D_o=4.4%)。芦笋精对LA-739小鼠肺腺癌实体瘤有抑制生长作用。肿瘤体积测定表明芦笋精使肿瘤平均倍增时间延迟了四天,抑瘤效力为1.5左右。低浓度芦笋原汁(1.0%-0.1%)可促进外周血T淋巴细胞转化增殖,是机体免疫功能的生物调节剂。与白细胞介素-2(IL-2)合用,提高IL-2效价两倍,C_(57)小鼠、正常人、肿瘤患者反应相似,依次略减。

We determined and comparied the plasma membrane lipid region fluidity of two tumor cell lines, the high-metastatic human lung adenocarcinoma cell line (Anip-973) and its low-metastatic parent cell line(AGZY-83a), by fluorescence polarization with a probe DPH (1,6-diphenyl-1,3,5-hexatriene). All tumor cells were synchronized at early S-phase by the double thymidine block. The results demonstrated that the membrane fluidity of the high-metastatic human lung adenocarcinoma cell line is significantly higher than...

We determined and comparied the plasma membrane lipid region fluidity of two tumor cell lines, the high-metastatic human lung adenocarcinoma cell line (Anip-973) and its low-metastatic parent cell line(AGZY-83a), by fluorescence polarization with a probe DPH (1,6-diphenyl-1,3,5-hexatriene). All tumor cells were synchronized at early S-phase by the double thymidine block. The results demonstrated that the membrane fluidity of the high-metastatic human lung adenocarcinoma cell line is significantly higher than its parent cell line, but there is no difference between them before synchronization.

本文应用荧光探剂DPH(1,6-dipheny1-1,3,5-hexatriene)及荧光偏振技术,对高转移性的人肺腺癌细胞系Anip-973及其低转移性的母系AGiY-83a,经S相(S-phase)同步后细胞膜的流动性进行了测定并作了对比分析。结果表明,高转移性的人肺腺癌细胞膜比其低转移性的母系细胞膜具有较大流动性。

 
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