To study the effect of manganese on actirity of nitric oxide synthase (NOS) in the filial rat's brain,parental pregnant rats were injected intraabdominally with 7 5mg/kg、15mg/kg、30mg/kg MnCl 2 for 8 times,every other day. Then the filal rats were killed after being born for 30days, which NOS of brain tissue was detected with histochemical technology and image analysis equipment.
Conclusion Exposure to high dose of deltamethrin in pregnant female rats would influence the activity of NOS of their filial rat brain and interfere the neurobehavioral development of their filial rats.
Conclusion The activity of GAD in caudate putamen nucleus and substantia Negra of brains of filial rat could be promoted after the pregnant rats exposed to MnCl_2,so that the level of Glu was decreased and level of GABA was increased in this area,and the ratio of Glu/GABA was decreased,thus filial rats's remembrance was weaken.
Result Average optical density and integral optical density of the NSE positive neuron in the substantia nigra and caudate putamen nucleus of 21-day-old filial rats in varied experimental groups(P<0.01,P<0.05)decreased significantly,as compared with those in control group.
The serum concentrations of thyroxine (T4) and triiodothyronine (T3) and the activities of iodothyronine 5' and 5-deiodinase (D2, D3) were measured in the brain of filial mice to study the influence of selenium on thyroid hormone metabolism.
The B cell activity in filial mice exposed to PCBs was directly assessed, using thymus independent antigen, DNP-Dextran.
The T cell helper activity in filial mice exposed to PCBs was determined with an adoptive cell transfer system of hapten primed B cells and carrier primed helper T cells.
Ytterbium and trace element distribution in brain and organic tissues of offspring rats after prenatal and postnatal exposure to
The aim of this study is to determine the ytterbium (Yb) and trace elements distribution in brain and organic tissues of offspring rats after prenatal and long-term exposure to Yb.
The accumulation of Yb in the brain, liver, and femur is observed; moreover, the levels of Fe, Cu, Mn, Zn, Ca, and Mg in the brain and organic tissues of offspring rats are also altered after Yb exposure.
Offspring rats showed T-cell immunodeficiency regardless of the lateralization of the trauma in their mothers; this was more severe after right-sided trauma (both mature and immature T-lymphocytes were affected).
The EMG pattern of evoked responses in offspring rats changed according to the lesions evoked by unilateral trauma in their mothers (in the muscles responsible for postural asymmetry).