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| | AIM To investigate the effect of platelet transfusion in patients with hematologic diseases and the influence factors. METHODS The apheresis platelets (AP) and platelet rich plasmas (PRP) were transfused to 79 patients (acute leukemia, 53 cases, aplastic anemia, 26 cases). Peripheral blood platelet counts were made at 1 h, 24 h after platelet transfusion. The effectiveness was assayed by correct count increment (CCI) and the influence factors were analyzed. RESULTS ①The CCI in AP group was much hig... | | 目的 探讨出血性血液病患者血小板输注效果及影响因素 .方法 79例血液病患者 (急性白血病 5 3例 ,再生障碍性贫血 2 6例 ) ,输注单采或多人份混合血小板悬液 ,1h和2 4h后检测外周血小板计数 ,以校正血小板计数增值 (CCI)判定输注效果并讨论其影响因素 .结果 1单采组 CCI显著高于混合组 (1h P<0 .0 5 ,2 4h P<0 .0 1) ;2 87.3%出血症状改善或消失 ;3急白感染组无效输注率为 5 0 .0 % ,非感染组 18.5 % (P<0 .0 1) ;4急性白血病 (AL)组无效输注率15 .1% ,再生障碍性贫血 (AA)组 46 .2 % .结论 血小板输注是治疗因血小板减少导致出血的有效措施 ,感染影响输注效果 ,再障组无效输注率高于急性白血病组 | | 文摘来源 | | Objective To evaluate the filtration effect of the filter designed to filtrate away the white blood cells from platelet concentrates and the clinical significance of the above-mentioned transfused to patients with hematological diseases. Method Leukecytepoor platelet concentrates by filtration through the PL type was used in 35 patients suffering from various hematological diseases. Before and after the performance of filtration, platelets and white blood cells were counted respectively. Result After fil... | | 目的 评价应用滤器去除白细胞的血小板悬液的过滤效果和血液病患者输注后的临床意义。方法 对35例血液病患者输注经PL型滤除白细胞输血器去除白细胞的血小板悬液 ,滤过前、后分别计数血小板及白细胞。结果 过滤后血小板回收率平均为 94 .9% ,白细胞去除率为 98% ,输注无效率为 13.5 % (均数 ) ;输注血小板后出血症状明显改善。结论 血液病患者输注滤过白细胞的血小板悬液 ,可减少血小板无效输注及同种免疫反应 ,具有较好的临床应用价值 | | 文摘来源 | | Objective:To explore the relationship between the determination of platelet antibodies with crossmatch types and effectiveness of platelet transfusion. Methods:Using SEPSA test and platelet crossmatching approach to screen compatible platelet. Results:The effectiveness of transfusion was determined from the posttransfusion CCI at 1 hour in 10 patients with hematologic disease, the effect rate was 88%. Conclusions:The platelet antibody screening and platelet crossmatching approach can be used to improve the... | | 目的 :探讨血小板抗体检测方法及其配型的应用与血小板输注疗效的关系。方法 :采用血小板血清学方法测定抗体及血小板配型。结果 :对 10例血液病血小板无效输注患者进行血小板配型输注 ,其有效率为88%。结论 :血小板无效输注的患者采用血小板抗体检测及配型输注 ,对提高血小板输注疗效是非常重要的措施。 | | 文摘来源 | |   | | << 更多相关文摘 |
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