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急性肝功能障碍
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  “急性肝功能障碍”译为未确定词的双语例句
     CORRELATION BETWEEN CHANGE OF SERUM TRANSAMINASE LDH ISOENZYME ACTIVITIES, AND SERUM ZINC CONCENTRATlON IN ACUTE HEPATIC INJURY
     急性肝功能障碍时大白鼠血清中锌含量的变化——与转氨酶、LDH同功酶的关系
短句来源
     Serum osteopontin levels in patients withacute liver dysfunction
     急性肝功能障碍患者血清骨桥蛋白水平
短句来源
     Applicability of the acute physiology and chronic health evaluation I (APACHE I ) scoring system inRuijin Hospital Ceneral Surgery ICU, from May l991 to September 1995 general surgery critical illness (in 182 cases),make on the appraise and the mortality Prediction Model (MPM) was used to judge the prognosis.
     为分析急性病理生理和慢性健康评分(APACHEⅡ)与外科危重病预告的关系、急性肝功能障碍和衰竭对APACHEⅡ评分及其预后预测意义的影响、探讨肝功不全参数的应用和意义,对1991年5月~1995年9月外科重症监护室(SICU)182例患者,根据转入时状况评分,此后定期再重复评分;
短句来源
     Objective To study the role of apoptosis and necrosis of hepatocytes in the pathogenis of acute liver dysfunctionfollowing severe trauma in rats.
     目的 探讨严重创伤后肝细胞凋亡及坏死在急性肝功能障碍发病机制中的作用。
短句来源
  相似匹配句对
     Serum osteopontin levels in patients withacute liver dysfunction
     急性肝功能障碍患者血清骨桥蛋白水平
短句来源
     Analysis on pathogenesis of coma
     急性意识障碍的病因分析
短句来源
     An Acute Experiment on Hypercapnia with Microcirculatory Stasis
     急性实验性高碳酸血症的微循环障碍
短句来源
     CLINICAL ANALYSIS OF 36 CASES OF CHRONIC MYELOID LEUKEMIA WITH BLAST CRISIS
     急性白血病患者的肝功能损害
短句来源
     Liver Function damage in Acute Pancreatitis
     急性胰腺炎时的肝功能损害
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  acute liver dysfunction
Neutralization of CXCL10 protected mice from acute liver dysfunction and diminished hepatocellular loss.
      
A case of solitary necrotic nodule of the liver with acute liver dysfunction: The imaging appearance correlated with pathologica
      
We report three subjects with TT I and acute liver dysfunction who had hyperinsulinism in early infancy.
      
Prothrombin time may be prolonged and is the best marker of the extent of acute liver dysfunction.
      


Traditional mongolian medicine Elighen Gurugum-7,Dedu Gurugum-7,

蒙药额力根·古日古木-7散、德都·古日古木-7散和蓝盆花等的水煎液5g/kg和2.5g/kg投药1次可提高由痤疮丙酸杆菌加脂多糖诱发急性肝功能障碍小鼠的生存率。同药间隔8h给药两次则明显降低由同上及D~氨基半乳糖加脂多糖和四氯化碳引起的肝损伤小鼠的血清丙氨酸氨基转移酶和天门冬氨酸氨基转移酶并显著减轻肝脏的病理损害;能提高由痤疮丙酸杆菌和D~氨基半乳糖分别加脂多糖诱发肝损伤小鼠的血清总蛋白和白蛋白。

Applicability of the acute physiology and chronic health evaluation I (APACHE I ) scoring system inRuijin Hospital Ceneral Surgery ICU, from May l991 to September 1995 general surgery critical illness (in 182 cases),make on the appraise and the mortality Prediction Model (MPM) was used to judge the prognosis. The results show themean APACHE II score was 18. 2±5. 6,calculated mortality and actual mortality appear directly in terrelated (31. 1 %vs34. 6% v= 0.98). The calculated moality was slightiy lower than...

Applicability of the acute physiology and chronic health evaluation I (APACHE I ) scoring system inRuijin Hospital Ceneral Surgery ICU, from May l991 to September 1995 general surgery critical illness (in 182 cases),make on the appraise and the mortality Prediction Model (MPM) was used to judge the prognosis. The results show themean APACHE II score was 18. 2±5. 6,calculated mortality and actual mortality appear directly in terrelated (31. 1 %vs34. 6% v= 0.98). The calculated moality was slightiy lower than the real mortality (P>0. 05). In 27 hepatic dysfunction cases, the mean APACHE I score was 20. 8±4. 6. The calculated mortality was markedly dower than the actual mortality (37. 5% vs70- 4%,P

为分析急性病理生理和慢性健康评分(APACHEⅡ)与外科危重病预告的关系、急性肝功能障碍和衰竭对APACHEⅡ评分及其预后预测意义的影响、探讨肝功不全参数的应用和意义,对1991年5月~1995年9月外科重症监护室(SICU)182例患者,根据转入时状况评分,此后定期再重复评分;用死亡率预测方程(MPM)预测病死率,和实际病死率相对比,并用肝功不全参数作校正。结果:本组平均APACHEⅡ评分18.22分,预测病况率略低于实际病死率。肝功能障碍/衰竭27例,平均APACHEⅡ评分为20.8分,预测病死率为37.5%,实际病死率为70.4%,差异有非常显著性(P<0.001)。给予肝功不全参数后全组预测病死率为35.3%,肝功能障碍/衰竭组为68.5%,校正后与实际差异无显著性。本文结果提示:APACHEⅡ评分在外科ICU中的应用有预测死亡率的作用。但因肝功能障碍评估不计入评分,使实际病死率高于预测病死率,因此在普外ICU应用时增加一个肝功不全校正参数。以增强其预测预后的意义。

Objective To study the role of apoptosis and necrosis of hepatocytes in the pathogenis of acute liver dysfunctionfollowing severe trauma in rats. Methods Rat models of multiple fractures complicated by shock were established, in whichapoptotic and necrotic hepatocytes were detected by flow cytometry (FCM) via double-staining technique of Annexin-V-flousand propidium iodide (PI). Observation of the pathological changes in the hepatocytes was also conducted by means of lightand electron microscopy and electronphoresis...

Objective To study the role of apoptosis and necrosis of hepatocytes in the pathogenis of acute liver dysfunctionfollowing severe trauma in rats. Methods Rat models of multiple fractures complicated by shock were established, in whichapoptotic and necrotic hepatocytes were detected by flow cytometry (FCM) via double-staining technique of Annexin-V-flousand propidium iodide (PI). Observation of the pathological changes in the hepatocytes was also conducted by means of lightand electron microscopy and electronphoresis respectively, and the correlation of these changes with liver function were eval-uated. Results Hepatocytes underwent both apoptosis and necrosis in rat models of severe theuma. The quantities ofnecrotichepatocytes increased progressively in positive correlation with the degree ofhepatic injury, reaching the peak at 3 h posttrau-ma. A proportion of the apoptotic cells underwent secondary necrosis, the number of the necrotic cells positively correlatedwith liver dysfunction deterioration. Conclusions Both necrosis and apoptosis are important factors responsible for liver func-tion damages following severe trauma. Necrosis of hepatic cells directly causes liver function damages that are further aggra-vated by secondary necrosis among apoptotic hepatocytes.

目的 探讨严重创伤后肝细胞凋亡及坏死在急性肝功能障碍发病机制中的作用。方法复制多发性骨折合并休克的大鼠创伤模型,采用 Annexin-V-Flous、碘化丙锭(propidium iodid,PI)双标法经流式细胞仪检测创伤后各时间点肝细胞凋亡与坏死的数量变化,结合光镜、电镜和电泳观察细胞凋亡与坏死,并与肝功能变化相比较。结果创伤后早期肝细胞即发生凋亡和坏死,坏死肝细胞的数量进行性升高,与肝功能变化显著呈正相关;凋亡肝细胞在创伤后3h达高峰,部分凋亡肝细胞发生继发性坏死,其数量与肝功能变化显著正相关。结论肝细胞坏死与凋亡是严重创伤后肝功能损害的重要原因,坏死肝细胞是肝功能损害的直接因素,凋亡肝细胞通过发生继发性坏死加重肝功能损害。

 
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