The matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) is one kind of“soft”ionization mass spectrometry which developed recently, compare to traditional analysis instrument like GC, HPLC, CE and other mass spectrometry ionization sources, MALDI has many advantages: high sensitivity, high flux;
基质辅助激光解吸电离飞行时间质谱(matrix-assisted laser desorption ionization time of flight mass spectrometry MALDI-TOF- MS)是最近发展起来的一种软电离质谱分析技术,与传统分析技术如气相色谱技术、液相色谱技术、毛细管电泳技术及其他质谱电离源分析技术相比较, MALDI具有灵敏度高; 高 通量;
The transdermal flux of insulin with less aggregation in the presence of CTAB was improved 3～5 fold with over 70% of the total transported insulin detected in the receiver compartment under pulses with the duration of 6～8 ms.
The transdermal transport of insulin was shown to be influenced by the pH of the donor solution with the highest transdermal insulin flux at pH of 4.0～5.0.
The decline of membrane flux
Methods:Piroxican,Methimazole,Hydrocortisone,Ibuprofen,and Chlorpromazine were studied across NZWR skin and Kunming mouse skin. The resulted permeation profile for each individual drug was analyzed by the lag time method to estimate parameters such as the steady state flux(Jss),lag time (Tlag),skin/donor phase partition coefficient(Km).
方法 :将吡罗昔康、甲巯咪唑、布洛芬、氢化可的松、盐酸氯丙嗪五种药物经鼠皮及新西兰家兔皮肤的体外经皮渗透数据 ,用滞时间法计算出稳态 通量 (Jss)、滞留时间 (Tlag)、扩散系数 (D)和皮肤 /供体分配系数 (Km )等参数。
Study on High Throughput Screening of Agonist for Neuromedin U2 Receptor and the Active Compounds of Nature Products
Neuromedin U2受体激动剂高 通量筛选模型与天然产物活性成分研究
High throughput screening for pharmaceutical activity compounds
Introduction of the High Throughput Screening System
Application of high throughput screening in drug development
Research in innovation of new drugs and high throughput screening technology
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The increased glucose flux through this metabolic pathway has been linked to the development of diabetic complications such as neuropathy, nephropathy, retinopathy, and cataract.
In diabetes, increased flux through the polyol pathway has been implicated in the development of diabetic complications such as cataract, retinopathy, neuropathy, and nephropathy.
At last, we also get the super-convergence estimates for total flux.
Research on a direct torque control for an electrically excited synchronous motor drive with low ripple in flux and torque
Therefore, the torque and stator flux linkage ripples are high in the direct torque control (DTC) drive of the ESM with a torque and flux linkage hysteresis controller (basic DTC).
This paper deals with asymptotic analysis of a parabolic system with inner absorptions and coupled nonlinear boundary fluxes.
Relations between carbon dioxide fluxes and environmental factors of Kobresia humilis meadows and Potentilla fruticosa meadows
There exists a negative correlation between the vegetation albedos and the carbon dioxide fluxes.
The fluxes of carbon dioxide generated during this degradation were deduced from differences in the carbon isotope abundance ratios of glucose δ13C = -11.4 per mil) and SOM δ13C = -27.01 per mil).
2D [1H,13C] NMR study of carbon fluxes during glucose utilization by Escherichia coli MG1655
Furthermore, the trends of the flux and charge rate with various speeds were analyzed.
The influence of the external dimensions, pole numbers and magnet thicknesses of the rotor, and the airgap distances on the flux density, are analyzed and analytical results are given.
With the increase of the airgap distance, the flux density under more poles reduces more quickly than under fewer poles.
With the increase of the magnet thickness, the flux density is a rising curve, and after the magnet thickness attains a certain point, the flux density is almost a constant.
While reducing the diameter of the rotor, the decrease of the flux density slows down as magnet thickness is reduced.
ADVANCES IN VIRTUAL HIGH THROUGHPUT SCREENING (v-HTS)
Detectability of 0.7 mg/l for pseudoephedrine hydrochloride was achieved at a sample throughput rate of 24 times per hour, which is 30% lower than that obtained by HDI-based conventional CE.
Research on switching throughput of traffic manager in core routers
A general model is made to analyze switching throughput of traffic manager in core routers.
A general relationship between throughput and buffering scheme of IP packets in the external memory is given, which is useful in the design of switch fabric in core routers.